Conserved Protein Domain Family
KxYKxGKxW

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TIGR03715: KxYKxGKxW 
KxYKxGKxW signal peptide
This model describes a novel form of signal peptide that occurs as an N-terminal domain with a recognizable motif, reminiscent of the YSIRK and PEP-CTERM forms of signal peptide. This domain tends to occur on long, low-complexity (usually Serine-rich and heavily glycosylated) proteins of the Firmicutes, and (as with YSIRK) the majority of these proteins have the LPXTG cell wall-anchoring motif at the C-terminus.
Statistics
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PSSM-Id: 274741
Aligned: 123 rows
Threshold Bit Score: 26.5829
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_04014070     6 RTNFKMYKIGRRWAFACAVILTM 28   Lactobacillus plantarum subsp. plantarum ATCC 14917
ZP_03211936     8 KTRYRLYKSGKLWLVALIGFFVL 30   Lactobacillus rhamnosus HN001
ZP_03913717    13 SERYKMYKAGKVWLFAGLSALVI 35   Leuconostoc mesenteroides subsp. cremoris ATCC 19254
ZP_04013930    14 SERFKLYKSGKLWLVAGLTFFSF 36   Lactobacillus plantarum subsp. plantarum ATCC 14917
ZP_04015159    40 TKRFKLYKSGKLWLVAGVTFCSF 62   Lactobacillus plantarum subsp. plantarum ATCC 14917
ZP_03211678    19 HVRFRMYKAKKRWLIAGTALLLM 41   Lactobacillus rhamnosus HN001
WP_023439820   20 KKRFHLYKSGKLWLVAGLATLSF 42   Pediococcus pentosaceus
Q939N5         16 VTRFKLIKSGKHWLRAATSQFGL 38   Streptococcus gordonii
WP_012515044    5 EGRFRTWKSKKQWLFAGAVVTSL 27   Streptococcus equi
WP_021166130   18 VTHFRTWKSGKKWVYAFMAFSLL 40   Lactococcus lactis
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