15675473 25 VKQEIDMt------PDSKEQTVTGYQYHYIDqEGRKQp---------FNQGWRFLMADVACaq-dPSFDDSNWQVIH--- 85 Streptococcus pyo... 15888848 7 ISSSTP---------ETV-IDLAGLWHLASV-EGDHA----------TEISIPGDIHSALKn---AAIIPDPYHGANeka 62 Agrobacterium tum... 15889832 1 MRTYLP---------GESEEVLSEGWTLTLTpADACE----------TPSDIPASLESLHVs--vPGTVGQALEAAGk-- 57 Agrobacterium tum... 15965678 8 MPSETPN-------RDAVRIDLSGDWLLAAA-DNSHA----------LTIALPGDVHSALQr---AGIIADPYRGRNead 66 Sinorhizobium mel... 15900551 117 APRIESQasnqekpLKEDAKAVTNEEVNQMIeDRKVD----------FNQNWYFKLNANSKeaikPDADVSTWKKLDl-p 185 Streptococcus pne... 15899743 1 -----------mrsFYRPKIDLQGFWKFKIDnENTGE-----------ENGWYKGLESED-----IIYVPASWNEQN--- 50 Sulfolobus solfat... 15643820 1 -----------------MVRPQRNKKRFILI----LN------------GVWNLEVTSKDR----PIAVPGSWNEQYq-- 41 Thermotoga maritima 15644372 1 ----------------MKRIDLNGFWSVRDN-EGRFS----------FEGTVPGVVQADLVr---KGLLPHPYVGMNedl 50 Thermotoga maritima 15837448 24 TASAAP--------PSS--HPLS-NWHLRLApDQPTTptlplktttwLPAHVPGTVQTDLIa---AGIVPDPFYRDQeaq 89 Xylella fastidios... 16130971 35 SYDSVAQartfareTSSLFLPLSGQWNFHFF-DHPLQ----------VPEAFTSELMADWG----HITVPAMWQMEG--- 96 Escherichia coli K12 15888848 7 ISSSTP---------ETV-IDLAGLWHLASV-EGDHA----------TEISIPGDIHSALKn---AAIIPDPYHGANeka 62 Agrobacterium tum... 15889832 1 MRTYLP---------GESEEVLSEGWTLTLTpADACE----------TPSDIPASLESLHVs--vPGTVGQALEAAGk-- 57 Agrobacterium tum... 15965678 8 MPSETPN-------RDAVRIDLSGDWLLAAA-DNSHA----------LTIALPGDVHSALQr---AGIIADPYRGRNead 66 Sinorhizobium mel... 15900551 117 APRIESQasnqekpLKEDAKAVTNEEVNQMIeDRKVD----------FNQNWYFKLNANSKeaikPDADVSTWKKLDl-p 185 Streptococcus pne... 15899743 1 -----------mrsFYRPKIDLQGFWKFKIDnENTGE-----------ENGWYKGLESED-----IIYVPASWNEQN--- 50 Sulfolobus solfat... 15643820 1 -----------------MVRPQRNKKRFILI----LN------------GVWNLEVTSKDR----PIAVPGSWNEQYq-- 41 Thermotoga maritima 15644372 1 ----------------MKRIDLNGFWSVRDN-EGRFS----------FEGTVPGVVQADLVr---KGLLPHPYVGMNedl 50 Thermotoga maritima 15837448 24 TASAAP--------PSS--HPLS-NWHLRLApDQPTTptlplktttwLPAHVPGTVQTDLIa---AGIVPDPFYRDQeaq 89 Xylella fastidios... 16130971 35 SYDSVAQartfareTSSLFLPLSGQWNFHFF-DHPLQ----------VPEAFTSELMADWG----HITVPAMWQMEG--- 96 Escherichia coli K12
15675473 86 LPHDFSLTQPYTRN---GEAEsAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFTY- 161 Streptococcus pyo... 15888848 63 VQWVAQQDWIIERTf-iLD---DAEASWYLDIDYLDTVAIVFVNDVPVLSADNCFRRYRPDISRAVRPGENTIRIHFHS- 137 Agrobacterium tum... 15889832 58 FDRLAPVALNDRDAwyrLTMIsDARERAILRFDGLSTIAEIFFNGELIAASQSMFERLEVPVQMTGADELSICFRALAP- 136 Agrobacterium tum... 15965678 67 VQWVARKDWVLERTv-vIDAD-DLNGGWYLDFESIDTVASVYVNDELVLQAENCFRRYRPDVSGAIVAGENRIRIVLHS- 143 Sinorhizobium mel... 15900551 186 YDWSIFNDFDHESPa--QNEG-GQLNGGEAWYRKTFKLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSY- 261 Streptococcus pne... 15899743 51 PKWDQFSGIAWYQKdlfVSND-NGNRKAWMVFEGAGYITKLWINGEYGGTHEGSFTQFKFPIKLKVNEFNKIVVKIDNT- 128 Sulfolobus solfat... 15643820 42 DLCYEEGPFTYKTTf-yVPKE-LSQKHIRLYFAAVNTDCEVFLNGEKVGENHIEYLPFEVDVTGKVKSGENELRVVVENr 119 Thermotoga maritima 15644372 51 FKEIEDREWIYEREf-eFKEDvKEGERVDLVFEGVDTLSDVYLNGVYLGSTEDMFIEYRFDVT-NVLKEKNHLKVYIKS- 127 Thermotoga maritima 15837448 90 IQWIGLNDWQYQTHf-hIDTAtLTRQHIELLFNGLDTLATVTLNGTPLLHPNNMFRRWRVDAKPLLKRGENILEITLYSp 168 Xylella fastidios... 16130971 97 HGKLQYTDEGFPFPi-dVPFV-PSDNPTGAYQRIFTLSDGWQGK-QTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF- 172 Escherichia coli K12 15888848 63 VQWVAQQDWIIERTf-iLD---DAEASWYLDIDYLDTVAIVFVNDVPVLSADNCFRRYRPDISRAVRPGENTIRIHFHS- 137 Agrobacterium tum... 15889832 58 FDRLAPVALNDRDAwyrLTMIsDARERAILRFDGLSTIAEIFFNGELIAASQSMFERLEVPVQMTGADELSICFRALAP- 136 Agrobacterium tum... 15965678 67 VQWVARKDWVLERTv-vIDAD-DLNGGWYLDFESIDTVASVYVNDELVLQAENCFRRYRPDVSGAIVAGENRIRIVLHS- 143 Sinorhizobium mel... 15900551 186 YDWSIFNDFDHESPa--QNEG-GQLNGGEAWYRKTFKLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSY- 261 Streptococcus pne... 15899743 51 PKWDQFSGIAWYQKdlfVSND-NGNRKAWMVFEGAGYITKLWINGEYGGTHEGSFTQFKFPIKLKVNEFNKIVVKIDNT- 128 Sulfolobus solfat... 15643820 42 DLCYEEGPFTYKTTf-yVPKE-LSQKHIRLYFAAVNTDCEVFLNGEKVGENHIEYLPFEVDVTGKVKSGENELRVVVENr 119 Thermotoga maritima 15644372 51 FKEIEDREWIYEREf-eFKEDvKEGERVDLVFEGVDTLSDVYLNGVYLGSTEDMFIEYRFDVT-NVLKEKNHLKVYIKS- 127 Thermotoga maritima 15837448 90 IQWIGLNDWQYQTHf-hIDTAtLTRQHIELLFNGLDTLATVTLNGTPLLHPNNMFRRWRVDAKPLLKRGENILEITLYSp 168 Xylella fastidios... 16130971 97 HGKLQYTDEGFPFPi-dVPFV-PSDNPTGAYQRIFTLSDGWQGK-QTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF- 172 Escherichia coli K12
15675473 162 --DISDVVTFGAENLLAVRV------ENKVPSSRWYSGSGLYR--EVSLSVLPQLHFVA--DQVAMTLADTAVQEKGQq- 228 Streptococcus pyo... 15888848 138 --NITAGAER-QARQPFYIPyh--pgNSPIANGNMLRKPQCHFgwDWNIAIAPLGLYGK--ILLKRLDTARIEHVVSS-- 208 Agrobacterium tum... 15889832 137 -------RLEKPGPRARWRPq-----MMNTQGLRLIRTTALGYmpGWCPEIHSAGPWRPi-SLIKQDGVLCTLRSSLDdt 203 Agrobacterium tum... 15965678 144 --AIAEGARR-QAAQPFYVPyh--dgNSPIANGNMLRKPQCHFgwDWNIAIAPLGIYGS--LALCRLETARIEHVTTR-- 214 Sinorhizobium mel... 15900551 262 --DITKYLQKDGRENVIAVHa-----VNKQPSSRWYSGSGIYR--DVTLQVTDKVHVEKngTTILTPKLEEQQHGKVEth 332 Streptococcus pne... 15899743 129 ---PSPYNLPPARDLNNAAF---------D----FFNYGGIHR--PVYIEFVDECHVED--ITVYTKSYGHLKVEILS-- 186 Sulfolobus solfat... 15643820 120 -lKVGGFPSKVPDSGTHTVGff---gSFPPANFDFFPYGGIIR--PVLIEFTDHARILD--IWVDTSESEPEKKLGKVk- 190 Thermotoga maritima 15644372 128 -----PIRVPKTLEQNYGVLg-----GPEDPIRGYIRKAQYSYgwDWGARIVTSGIWKP--VYLEVYRARLQDSTAYLle 195 Thermotoga maritima 15837448 169 ikKIQPWLTQQPYALPGAYDsafhdePTARHSATYVRKAPYQFgwDWGPRIVTTGLWKN--VTLDTWDTTRINDLHIA-- 244 Xylella fastidios... 16130971 173 --DISAMVKTGDNLLCVRVMqw--adSTYVEDQDMWWSAGIFR--DVYLVGKHLTHIND--FTVRTDFDEAYCDATLSc- 243 Escherichia coli K12 15888848 138 --NITAGAER-QARQPFYIPyh--pgNSPIANGNMLRKPQCHFgwDWNIAIAPLGLYGK--ILLKRLDTARIEHVVSS-- 208 Agrobacterium tum... 15889832 137 -------RLEKPGPRARWRPq-----MMNTQGLRLIRTTALGYmpGWCPEIHSAGPWRPi-SLIKQDGVLCTLRSSLDdt 203 Agrobacterium tum... 15965678 144 --AIAEGARR-QAAQPFYVPyh--dgNSPIANGNMLRKPQCHFgwDWNIAIAPLGIYGS--LALCRLETARIEHVTTR-- 214 Sinorhizobium mel... 15900551 262 --DITKYLQKDGRENVIAVHa-----VNKQPSSRWYSGSGIYR--DVTLQVTDKVHVEKngTTILTPKLEEQQHGKVEth 332 Streptococcus pne... 15899743 129 ---PSPYNLPPARDLNNAAF---------D----FFNYGGIHR--PVYIEFVDECHVED--ITVYTKSYGHLKVEILS-- 186 Sulfolobus solfat... 15643820 120 -lKVGGFPSKVPDSGTHTVGff---gSFPPANFDFFPYGGIIR--PVLIEFTDHARILD--IWVDTSESEPEKKLGKVk- 190 Thermotoga maritima 15644372 128 -----PIRVPKTLEQNYGVLg-----GPEDPIRGYIRKAQYSYgwDWGARIVTSGIWKP--VYLEVYRARLQDSTAYLle 195 Thermotoga maritima 15837448 169 ikKIQPWLTQQPYALPGAYDsafhdePTARHSATYVRKAPYQFgwDWGPRIVTTGLWKN--VTLDTWDTTRINDLHIA-- 244 Xylella fastidios... 16130971 173 --DISAMVKTGDNLLCVRVMqw--adSTYVEDQDMWWSAGIFR--DVYLVGKHLTHIND--FTVRTDFDEAYCDATLSc- 243 Escherichia coli K12
15675473 229 --KVDLRFALNQsiqtchYQLSLCLWEQSHCSKDKKLlyqe------tevpLaDLAFQRQYGLTLSLEELQLWSPD---N 297 Streptococcus pyo... 15888848 209 -----QHHVEGGv----eLHVAVTLFAEGPASLPVYLslgde----rlrleCgVGAGETVVRHVFFVENPDLWWP----A 271 Agrobacterium tum... 15889832 204 gtGKVSIVLQANr-----DIQSARLICAGYSINLS-------------------KAEDGKLLGELIIPGVEIWWPHthgR 259 Agrobacterium tum... 15965678 215 -----QMWLDDGsv---dLQVTVQLFAREPGIVPVHFmldgv----rerldCaVGAGETRLTHVFTVQEPRRWWP----A 278 Sinorhizobium mel... 15900551 333 vtSKIVNTDDKDh----eLVAEYQIVERGGHAVTGLVrta---------srTlKAHESTSLDAILEVERPKLWTVLn-dK 398 Streptococcus pne... 15899743 187 -----ECNQRFS-------LR-FKLVDKEGRVILN--------------------EESSNEVFEKDVNNVIPWSPD---N 230 Sulfolobus solfat... 15643820 191 --VKIEVSEEAVg-----QEMTIKLGEEEKKIRTS----------------------NRFVEGEFILENARFWSLE---D 238 Thermotoga maritima 15644372 196 leGKDALVRVNGfvh-geGNLIVEVYVNGEKIGEFPv-------------lE--KNGEKLFDGVFHLKDVKLWYPWnvgK 259 Thermotoga maritima 15837448 245 -----QQRVDADtah-leAQLTLDATHRGPAHITLQVidpdgrpiaqyhqhPtLDTGPNHIHLPVRIAQPRRWFPVgygA 318 Xylella fastidios... 16130971 244 -eVVLENLAASPv----vTTLEYTLFDGERVVHSsa-------------idHlAIEKLTSATFAFTVEQPQQWSAE---S 302 Escherichia coli K12 15888848 209 -----QHHVEGGv----eLHVAVTLFAEGPASLPVYLslgde----rlrleCgVGAGETVVRHVFFVENPDLWWP----A 271 Agrobacterium tum... 15889832 204 gtGKVSIVLQANr-----DIQSARLICAGYSINLS-------------------KAEDGKLLGELIIPGVEIWWPHthgR 259 Agrobacterium tum... 15965678 215 -----QMWLDDGsv---dLQVTVQLFAREPGIVPVHFmldgv----rerldCaVGAGETRLTHVFTVQEPRRWWP----A 278 Sinorhizobium mel... 15900551 333 vtSKIVNTDDKDh----eLVAEYQIVERGGHAVTGLVrta---------srTlKAHESTSLDAILEVERPKLWTVLn-dK 398 Streptococcus pne... 15899743 187 -----ECNQRFS-------LR-FKLVDKEGRVILN--------------------EESSNEVFEKDVNNVIPWSPD---N 230 Sulfolobus solfat... 15643820 191 --VKIEVSEEAVg-----QEMTIKLGEEEKKIRTS----------------------NRFVEGEFILENARFWSLE---D 238 Thermotoga maritima 15644372 196 leGKDALVRVNGfvh-geGNLIVEVYVNGEKIGEFPv-------------lE--KNGEKLFDGVFHLKDVKLWYPWnvgK 259 Thermotoga maritima 15837448 245 -----QQRVDADtah-leAQLTLDATHRGPAHITLQVidpdgrpiaqyhqhPtLDTGPNHIHLPVRIAQPRRWFPVgygA 318 Xylella fastidios... 16130971 244 -eVVLENLAASPv----vTTLEYTLFDGERVVHSsa-------------idHlAIEKLTSATFAFTVEQPQQWSAE---S 302 Escherichia coli K12
15675473 298 PHLYDLELTLYYQG-QVIDCFCLETGFRQLTFMANq-------GLFVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLV 369 Streptococcus pyo... 15888848 272 GSGEQTLYKLTVE--LPDETVTRQIGFRTIELLTDkdeagsrfAFRINGREIFCRGANWIPADALYSLTSREK-TEDLLC 348 Agrobacterium tum... 15889832 260 PALHEVVLELDGN-----QHRLGRTGFRQVEIDHGedg--ngfGLKVNGQPVFCRGAVWTTADIVRLPGTRPD-YEPWLK 331 Agrobacterium tum... 15965678 279 GSGDQAFSTLKVE--VPGETVTRQIGFRTIELVTDkdeagsrfAFRVNGREIFCRGANWIPADALMSRVTPES-VEDLLR 355 Sinorhizobium mel... 15900551 399 PALYELITRVYRDg-QLVDAKKDLFGYRYYHWTPNe-------GFSLNGERIKFHGVSLHHDHGALGAEENYKAEYRRLK 470 Streptococcus pne... 15899743 231 PYLYTLIVEMYVGg-NLKDSVYERIGFRDVEVKDG--------KIYLNGKPIFLKGFGRHEDFPILGKFTYGAVLVRDFY 301 Sulfolobus solfat... 15643820 239 PYLYPLKVELEKD------EYTLDIGIRTISWDEK--------RLYLNGKPVFLKGFGKHEEFPVLGQGTFYPLMIKDFN 304 Thermotoga maritima 15644372 260 PYLYDFVFVLKDLN-GEIYREEKKIGLRRVRIVQEpdeegktfIFEINGEKVFAKGANWIPSENILTWLKEED-YEKLVK 337 Thermotoga maritima 15837448 319 PDRYTFKATVRDAAgT-IQHIERITGLRTITLRREpdqwgksmALVVNGIPIFAKGANLIPFDSIPSRVTEAT-IRRTLQ 396 Xylella fastidios... 16130971 303 PYLYHLVMTLKDANgNVLEVVPQRVGFRDIKVRDG--------LFWINNRYVMLHGVNRHDNDHRKGRAVGMDRVEKDLQ 374 Escherichia coli K12 15888848 272 GSGEQTLYKLTVE--LPDETVTRQIGFRTIELLTDkdeagsrfAFRINGREIFCRGANWIPADALYSLTSREK-TEDLLC 348 Agrobacterium tum... 15889832 260 PALHEVVLELDGN-----QHRLGRTGFRQVEIDHGedg--ngfGLKVNGQPVFCRGAVWTTADIVRLPGTRPD-YEPWLK 331 Agrobacterium tum... 15965678 279 GSGDQAFSTLKVE--VPGETVTRQIGFRTIELVTDkdeagsrfAFRVNGREIFCRGANWIPADALMSRVTPES-VEDLLR 355 Sinorhizobium mel... 15900551 399 PALYELITRVYRDg-QLVDAKKDLFGYRYYHWTPNe-------GFSLNGERIKFHGVSLHHDHGALGAEENYKAEYRRLK 470 Streptococcus pne... 15899743 231 PYLYTLIVEMYVGg-NLKDSVYERIGFRDVEVKDG--------KIYLNGKPIFLKGFGRHEDFPILGKFTYGAVLVRDFY 301 Sulfolobus solfat... 15643820 239 PYLYPLKVELEKD------EYTLDIGIRTISWDEK--------RLYLNGKPVFLKGFGKHEEFPVLGQGTFYPLMIKDFN 304 Thermotoga maritima 15644372 260 PYLYDFVFVLKDLN-GEIYREEKKIGLRRVRIVQEpdeegktfIFEINGEKVFAKGANWIPSENILTWLKEED-YEKLVK 337 Thermotoga maritima 15837448 319 PDRYTFKATVRDAAgT-IQHIERITGLRTITLRREpdqwgksmALVVNGIPIFAKGANLIPFDSIPSRVTEAT-IRRTLQ 396 Xylella fastidios... 16130971 303 PYLYHLVMTLKDANgNVLEVVPQRVGFRDIKVRDG--------LFWINNRYVMLHGVNRHDNDHRKGRAVGMDRVEKDLQ 374 Escherichia coli K12
15675473 370 LLKDMGANTIRST--HNPSSPKLRQLANRLGFFVIEEAFDTWTYAKngnvndfsnyfhqtigtenanylqrVRSPETSWA 447 Streptococcus pyo... 15888848 349 SAVEANMNMIRVWggGFYEEDWFYDLCDRLGLLVWQDFMFACNLYP-------------------------CSEDFLDNV 403 Agrobacterium tum... 15889832 332 KAAEAGMNMIRVGgtMAYETPEFFALCDELGIMVWQDAMLANFDYPa------------------------KDDGLRQHI 387 Agrobacterium tum... 15965678 356 SAVDANMNMIRVWggGFYEPDWFYDLCDRLGLLVWQDFMFACNLYP-------------------------STPDFLENV 410 Sinorhizobium mel... 15900551 471 QMKEMGVNSIRTT--HNPASEQTLQIAAELGLLVQEEAFDTWYGGKkpydygrf---------fekdathpEARKGEKWS 539 Streptococcus pne... 15899743 302 LMRKIGANSFRTS--HYPYSNEHLDLADEMGFLVILEPPLCYSNISrvmsqe-------------eiakmfGDVKYFEKV 366 Sulfolobus solfat... 15643820 305 LLKWINANSFRTS--HYPYSEEWLDLADRLGILVIDEAPHVGITRYh------------------------YNPETQKIA 358 Thermotoga maritima 15644372 338 MARSANMNMLRVWggGIYEREIFYRLCDELGIMVWQDFMYACLEYPd------------------------HLPWFRKLA 393 Thermotoga maritima 15837448 397 DARAANMNMLRVWggGHYQDEHFYALADALGIMIWQDFMFGGAIPP-------------------------DDVDFRENV 451 Xylella fastidios... 16130971 375 LMKQHNINSVRTA--HYPNDPRFYELCDIYGLFVMAETDVESHGFAnvgdi----------------sritDDPQWEKVY 436 Escherichia coli K12 15888848 349 SAVEANMNMIRVWggGFYEEDWFYDLCDRLGLLVWQDFMFACNLYP-------------------------CSEDFLDNV 403 Agrobacterium tum... 15889832 332 KAAEAGMNMIRVGgtMAYETPEFFALCDELGIMVWQDAMLANFDYPa------------------------KDDGLRQHI 387 Agrobacterium tum... 15965678 356 SAVDANMNMIRVWggGFYEPDWFYDLCDRLGLLVWQDFMFACNLYP-------------------------STPDFLENV 410 Sinorhizobium mel... 15900551 471 QMKEMGVNSIRTT--HNPASEQTLQIAAELGLLVQEEAFDTWYGGKkpydygrf---------fekdathpEARKGEKWS 539 Streptococcus pne... 15899743 302 LMRKIGANSFRTS--HYPYSNEHLDLADEMGFLVILEPPLCYSNISrvmsqe-------------eiakmfGDVKYFEKV 366 Sulfolobus solfat... 15643820 305 LLKWINANSFRTS--HYPYSEEWLDLADRLGILVIDEAPHVGITRYh------------------------YNPETQKIA 358 Thermotoga maritima 15644372 338 MARSANMNMLRVWggGIYEREIFYRLCDELGIMVWQDFMYACLEYPd------------------------HLPWFRKLA 393 Thermotoga maritima 15837448 397 DARAANMNMLRVWggGHYQDEHFYALADALGIMIWQDFMFGGAIPP-------------------------DDVDFRENV 451 Xylella fastidios... 16130971 375 LMKQHNINSVRTA--HYPNDPRFYELCDIYGLFVMAETDVESHGFAnvgdi----------------sritDDPQWEKVY 436 Escherichia coli K12
15675473 448 QYSIEAMVWSAKNDPSVLMWSIGNELMEgfsadvshyPELTRQMCQWITAIDTSRPITFGDNKlkeadfcwHEEVSQMAT 527 Streptococcus pyo... 15888848 404 EHEVDYQVKRLSSHPSIALWCGDNE---------------LVGALTWFDESRNNRDRYLVAYD--------RLNRTIEKA 460 Agrobacterium tum... 15889832 388 VMEIEQLLESTALSPSFAIFCGGSE----------------MYQQGAMLGLPEQIWKGTLTEE---------I---LPEL 439 Agrobacterium tum... 15965678 411 AAEVDYQVRRLSTHPSLALWCGDNE---------------LVGALTWFEESRRDRDRYLVSYD--------RLNRTVEAV 467 Sinorhizobium mel... 15900551 540 DFDLRTMVERGKNNPAIFMWSIGNEIGEangd--ahsLATVKRLVKVIKDVDKTRYVTMGADK---------FRFGNGSG 608 Streptococcus pne... 15899743 367 RDTIKEMIRQHKNRPSVIMYSVMNE---------------PPSDIREVAEFIRREVELFKSLD---------SSRPVTFA 422 Sulfolobus solfat... 15643820 359 EDNIRRMIDRHKNHPSVIMWSVANEPE-----------SNHPDAEGFFKALYETANEMDRTRP--------VVMVSMMDA 419 Thermotoga maritima 15644372 394 NEEARKIVRKLRYHPSIVLWCGNNE--------------NNWGFDEWGNMARKVDGINLGNRL---------YLFDFPEI 450 Thermotoga maritima 15837448 452 RQEAIEQLTRLRDHPSIVLWCGNNEVQT---------GWEHWGDRITFKQSLPPEERSNIERG---------MTTLFGSV 513 Xylella fastidios... 16130971 437 VERIVRHIHAQKNHPSIIIWSLGNESGY---------GCNIRAMYHAAKALDDTRLVHYEEDRd-------AEVVDIIST 500 Escherichia coli K12 15888848 404 EHEVDYQVKRLSSHPSIALWCGDNE---------------LVGALTWFDESRNNRDRYLVAYD--------RLNRTIEKA 460 Agrobacterium tum... 15889832 388 VMEIEQLLESTALSPSFAIFCGGSE----------------MYQQGAMLGLPEQIWKGTLTEE---------I---LPEL 439 Agrobacterium tum... 15965678 411 AAEVDYQVRRLSTHPSLALWCGDNE---------------LVGALTWFEESRRDRDRYLVSYD--------RLNRTVEAV 467 Sinorhizobium mel... 15900551 540 DFDLRTMVERGKNNPAIFMWSIGNEIGEangd--ahsLATVKRLVKVIKDVDKTRYVTMGADK---------FRFGNGSG 608 Streptococcus pne... 15899743 367 RDTIKEMIRQHKNRPSVIMYSVMNE---------------PPSDIREVAEFIRREVELFKSLD---------SSRPVTFA 422 Sulfolobus solfat... 15643820 359 EDNIRRMIDRHKNHPSVIMWSVANEPE-----------SNHPDAEGFFKALYETANEMDRTRP--------VVMVSMMDA 419 Thermotoga maritima 15644372 394 NEEARKIVRKLRYHPSIVLWCGNNE--------------NNWGFDEWGNMARKVDGINLGNRL---------YLFDFPEI 450 Thermotoga maritima 15837448 452 RQEAIEQLTRLRDHPSIVLWCGNNEVQT---------GWEHWGDRITFKQSLPPEERSNIERG---------MTTLFGSV 513 Xylella fastidios... 16130971 437 VERIVRHIHAQKNHPSIIIWSLGNESGY---------GCNIRAMYHAAKALDDTRLVHYEEDRd-------AEVVDIIST 500 Escherichia coli K12
15675473 528 LLSQLDHPQGLIGLNyadgkdydrlheehSDWLLYgsetvsaitsrayyketkkvLDSGYHLTSYDHAKVDWGAFASqaw 607 Streptococcus pyo... 15888848 461 LKKATPEALWWPSSP--------------ASGYLD--------------------YGDAWHADG-SGDMHYWSVWHE--- 502 Agrobacterium tum... 15889832 440 VAEKRPDAAYVANSP--------------SGGALP--------------------FFPNAGVGHYYGVGAYCRPLED--- 482 Agrobacterium tum... 15965678 468 MKQACPEAIWWPSSP--------------SVGYLD--------------------FGDAWHADG-AGDMHYWSVWHE--- 509 Sinorhizobium mel... 15900551 609 GHEKIADELDAVGFN-----------------------------------------YSEDNYKALRAKHPKWLIYGS--- 644 Streptococcus pne... 15899743 423 SHRSVR------------------------DLALE--------------------YVDVISLNYYHGWYTEWGDIDSg-- 456 Sulfolobus solfat... 15643820 420 PDERTR------------------------DVALK--------------------YFDIVCVNRYYGWYIYQGRIEEg-- 453 Thermotoga maritima 15644372 451 CAEEDPSTPYWPSSP------------------Y----------------------GGEKANSEKEGDRHVWYVWSG--- 487 Thermotoga maritima 15837448 514 LREAVH--LYSPGTPyw----------atSPGTDL--------------------DGPAEQTND--GDMHYWKVWG---- 555 Xylella fastidios... 16130971 501 MYTRVPLMNEFGEYPh------------pKPRIIC--------------------EYAHAMGNGPGGLTEYQNVFYK--- 545 Escherichia coli K12 15888848 461 LKKATPEALWWPSSP--------------ASGYLD--------------------YGDAWHADG-SGDMHYWSVWHE--- 502 Agrobacterium tum... 15889832 440 VAEKRPDAAYVANSP--------------SGGALP--------------------FFPNAGVGHYYGVGAYCRPLED--- 482 Agrobacterium tum... 15965678 468 MKQACPEAIWWPSSP--------------SVGYLD--------------------FGDAWHADG-AGDMHYWSVWHE--- 509 Sinorhizobium mel... 15900551 609 GHEKIADELDAVGFN-----------------------------------------YSEDNYKALRAKHPKWLIYGS--- 644 Streptococcus pne... 15899743 423 SHRSVR------------------------DLALE--------------------YVDVISLNYYHGWYTEWGDIDSg-- 456 Sulfolobus solfat... 15643820 420 PDERTR------------------------DVALK--------------------YFDIVCVNRYYGWYIYQGRIEEg-- 453 Thermotoga maritima 15644372 451 CAEEDPSTPYWPSSP------------------Y----------------------GGEKANSEKEGDRHVWYVWSG--- 487 Thermotoga maritima 15837448 514 LREAVH--LYSPGTPyw----------atSPGTDL--------------------DGPAEQTND--GDMHYWKVWG---- 555 Xylella fastidios... 16130971 501 MYTRVPLMNEFGEYPh------------pKPRIIC--------------------EYAHAMGNGPGGLTEYQNVFYK--- 545 Escherichia coli K12
15675473 608 ydtitRDFVAGECVWTGFDYLGEP-TPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYyfYQSQWAQGQTTLHLLPVW 686 Streptococcus pyo... 15888848 503 -----NKSFDN---YHQVKPRFCS--EFGFQSYTSMPVIRTYAEDKDMNIASPVIELHQK--NVGGNERIAGTMFRYFRF 570 Agrobacterium tum... 15889832 483 -----ARRADLRFAAECLAFANIPeQETLDRYLPGVAVHDPRWKARTPRDRGASWDFEDV---RDHYLKLLYEAEPDVLR 554 Agrobacterium tum... 15965678 510 -----NKSFDN---YRTVRPRFCS--EFGFQSYTSMQVIRQFAEAHDLNIASPVMEAHQK--NAGGNERIAGTMFRYFRF 577 Sinorhizobium mel... 15900551 645 -----ETSSATRTRGSYYRPERELkHSNGPERNYEQSDYGNDRVGWGKTATASWTFDRDN---AGYAGQFIWTGTDYIGE 716 Streptococcus pne... 15899743 457 -----VKVVAIELEEIHKKFPEKPiIITEFGADAIYGLHSDPPQMWSEEYQSEMIRKYIE--ALREKDYIVGFHIWNFAD 529 Sulfolobus solfat... 15643820 454 -----LQALEKD-IEELYARHRKPiFVTEFGADAIAGIHYDPPQMFSEEYQAELVEKTIR--LLLKKDYIIGTHVWAFAD 525 Thermotoga maritima 15644372 488 -----WMNYEN---YEKDTGRFIS--EFGFQGAPHPETIEFFSKPEEREIFHPVMLKHNK--QVEGQERLIRFIFGNFGK 555 Thermotoga maritima 15837448 556 -----NPALPVT-EYLNITPRFMS--EYGLQSFPDIRTIRTFARPEDLSLTSQVMRAHQKfdNGNGNQRLLLYIRRAFGE 627 Xylella fastidios... 16130971 546 -----HDCIQGHYVWEWCDHGIQAqDDHGNVWYKFGGDYGDYPNNYNFCLDGLIYSDQTP--GPGLKEYKQVIAPVKIHA 618 Escherichia coli K12 15888848 503 -----NKSFDN---YHQVKPRFCS--EFGFQSYTSMPVIRTYAEDKDMNIASPVIELHQK--NVGGNERIAGTMFRYFRF 570 Agrobacterium tum... 15889832 483 -----ARRADLRFAAECLAFANIPeQETLDRYLPGVAVHDPRWKARTPRDRGASWDFEDV---RDHYLKLLYEAEPDVLR 554 Agrobacterium tum... 15965678 510 -----NKSFDN---YRTVRPRFCS--EFGFQSYTSMQVIRQFAEAHDLNIASPVMEAHQK--NAGGNERIAGTMFRYFRF 577 Sinorhizobium mel... 15900551 645 -----ETSSATRTRGSYYRPERELkHSNGPERNYEQSDYGNDRVGWGKTATASWTFDRDN---AGYAGQFIWTGTDYIGE 716 Streptococcus pne... 15899743 457 -----VKVVAIELEEIHKKFPEKPiIITEFGADAIYGLHSDPPQMWSEEYQSEMIRKYIE--ALREKDYIVGFHIWNFAD 529 Sulfolobus solfat... 15643820 454 -----LQALEKD-IEELYARHRKPiFVTEFGADAIAGIHYDPPQMFSEEYQAELVEKTIR--LLLKKDYIIGTHVWAFAD 525 Thermotoga maritima 15644372 488 -----WMNYEN---YEKDTGRFIS--EFGFQGAPHPETIEFFSKPEEREIFHPVMLKHNK--QVEGQERLIRFIFGNFGK 555 Thermotoga maritima 15837448 556 -----NPALPVT-EYLNITPRFMS--EYGLQSFPDIRTIRTFARPEDLSLTSQVMRAHQKfdNGNGNQRLLLYIRRAFGE 627 Xylella fastidios... 16130971 546 -----HDCIQGHYVWEWCDHGIQAqDDHGNVWYKFGGDYGDYPNNYNFCLDGLIYSDQTP--GPGLKEYKQVIAPVKIHA 618 Escherichia coli K12
15675473 687 QKDQLCfdeqGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTYQLYQGadaAKNPHEnLYLTWRVPYQK 766 Streptococcus pyo... 15888848 571 PRDFEN----FVYLSQVQQALAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVASWSSLDY---GGGWKAlHYAARRFFQPV 643 Agrobacterium tum... 15889832 555 REDGAL----YLDMSRAATAEVMEATFAEWRRSGSSCQGALVWTLQDLVPGAGWGIIDA---AGRPKSvWHALKRAFRPV 627 Agrobacterium tum... 15965678 578 PKDFPS----FVYLSQIQQGLAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVASWSSLDY---GGHWKAmHYMARRFFQPV 650 Sinorhizobium mel... 15900551 717 PTPWHN-----QNQTPVKSSYFGIVDTAGIPKHDFYLYQSQWVSVKKKPMVHLLPHWNW-----ENKE---LASKVADSE 783 Streptococcus pne... 15899743 530 FRTPQN----PSRTILNRKGIFTRDRQPKLAAKVVEELFKNKLRS----------------------------------- 570 Sulfolobus solfat... 15643820 526 FKTPQN----VRRPILNHKGVFTRDRQPKLVAHVLRRLWSEV-------------------------------------- 563 Thermotoga maritima 15644372 556 CKDFDS----FVYLSQLNQAEAIKFGVEHWRSRKYKTAGALFWQFNDSWPVFSWSAVDY---FKRPKAlYYYARRFFAEV 628 Thermotoga maritima 15837448 628 PKDFES----FIYLSQLMQAEGIAIAAQHLRAARPQTMGSLYWQLNDVWPGASWSSIDY---AGRWKAlHYYTRRFYAPL 700 Xylella fastidios... 16130971 619 RDLTRGe---LKVENKLWFTTLDDYTLHAEVRAEGETLATQQIKLRDVAPNSEAPLQITl-pQLDARE-AFLNITVTKDS 693 Escherichia coli K12 15888848 571 PRDFEN----FVYLSQVQQALAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVASWSSLDY---GGGWKAlHYAARRFFQPV 643 Agrobacterium tum... 15889832 555 REDGAL----YLDMSRAATAEVMEATFAEWRRSGSSCQGALVWTLQDLVPGAGWGIIDA---AGRPKSvWHALKRAFRPV 627 Agrobacterium tum... 15965678 578 PKDFPS----FVYLSQIQQGLAIRTAVDYWRSLKPHCMGTLYWQLNDTWPVASWSSLDY---GGHWKAmHYMARRFFQPV 650 Sinorhizobium mel... 15900551 717 PTPWHN-----QNQTPVKSSYFGIVDTAGIPKHDFYLYQSQWVSVKKKPMVHLLPHWNW-----ENKE---LASKVADSE 783 Streptococcus pne... 15899743 530 FRTPQN----PSRTILNRKGIFTRDRQPKLAAKVVEELFKNKLRS----------------------------------- 570 Sulfolobus solfat... 15643820 526 FKTPQN----VRRPILNHKGVFTRDRQPKLVAHVLRRLWSEV-------------------------------------- 563 Thermotoga maritima 15644372 556 CKDFDS----FVYLSQLNQAEAIKFGVEHWRSRKYKTAGALFWQFNDSWPVFSWSAVDY---FKRPKAlYYYARRFFAEV 628 Thermotoga maritima 15837448 628 PKDFES----FIYLSQLMQAEGIAIAAQHLRAARPQTMGSLYWQLNDVWPGASWSSIDY---AGRWKAlHYYTRRFYAPL 700 Xylella fastidios... 16130971 619 RDLTRGe---LKVENKLWFTTLDDYTLHAEVRAEGETLATQQIKLRDVAPNSEAPLQITl-pQLDARE-AFLNITVTKDS 693 Escherichia coli K12
15675473 767 GLLRAVAydiSGKSIPKTSGRSqvrtygsvaklswKAFEAPIDapwELLYLDLSLLDSrgelvshaqDWLQVQVEGPARl 846 Streptococcus pyo... 15888848 644 AVSAIPS---ADGRRVTFSMVNd-----------tAEDVEIDM----NIVALAMDGNR---------VPLKSANGTCTS- 695 Agrobacterium tum... 15889832 628 QVSLSDEgtnGLDIHILNDTGD-------------SLNTMLELtclREGLQPVVHAKRp-------lALLPRESQTIAAt 687 Agrobacterium tum... 15965678 651 AVAAIPS---ADGREIAFSMVNd-----------tAEPATVEL----QAFLVSLDGNR---------QRLLAAAGTCPA- 702 Sinorhizobium mel... 15900551 784 GKIPVRAysnASSVELFLNGKSlg----------lKTFNKKQTs--DGRTYQEGANANe--------LYLEWKVAYQPGt 843 Streptococcus pne... 15899743 -------------------------------------------------------------------------------- Sulfolobus solfat... 15643820 -------------------------------------------------------------------------------- Thermotoga maritima 15644372 629 LPVLKKR-----DNKIELLVVS-------------DLRETKEVs--LRLAAYEKKGEK----------VFEKTYRTVLP- 677 Thermotoga maritima 15837448 701 MIAALRK-----DGMTTVSLVSd-----------rTTPLHVHW----RLRVLDMDGTP---------HHTDDQHTTLPP- 750 Xylella fastidios... 16130971 694 RTRYSEAghpIATYQFPLKENTaqpvp---fapnnARPLTLEDd--RLSCTVRGYNFA---------ITFSKMSGKPTSw 759 Escherichia coli K12 15888848 644 AVSAIPS---ADGRRVTFSMVNd-----------tAEDVEIDM----NIVALAMDGNR---------VPLKSANGTCTS- 695 Agrobacterium tum... 15889832 628 QVSLSDEgtnGLDIHILNDTGD-------------SLNTMLELtclREGLQPVVHAKRp-------lALLPRESQTIAAt 687 Agrobacterium tum... 15965678 651 AVAAIPS---ADGREIAFSMVNd-----------tAEPATVEL----QAFLVSLDGNR---------QRLLAAAGTCPA- 702 Sinorhizobium mel... 15900551 784 GKIPVRAysnASSVELFLNGKSlg----------lKTFNKKQTs--DGRTYQEGANANe--------LYLEWKVAYQPGt 843 Streptococcus pne... 15899743 -------------------------------------------------------------------------------- Sulfolobus solfat... 15643820 -------------------------------------------------------------------------------- Thermotoga maritima 15644372 629 LPVLKKR-----DNKIELLVVS-------------DLRETKEVs--LRLAAYEKKGEK----------VFEKTYRTVLP- 677 Thermotoga maritima 15837448 701 MIAALRK-----DGMTTVSLVSd-----------rTTPLHVHW----RLRVLDMDGTP---------HHTDDQHTTLPP- 750 Xylella fastidios... 16130971 694 RTRYSEAghpIATYQFPLKENTaqpvp---fapnnARPLTLEDd--RLSCTVRGYNFA---------ITFSKMSGKPTSw 759 Escherichia coli K12
15675473 847 lALDNgnptdhtpyqePLRQAYGGKllailaltgEAGHIKVTAKAsqqLSSVFQTQVACRAPKEHLVTLPLEKYQFKKSR 926 Streptococcus pyo... 15888848 696 ---DK-----------AATLTDIDMd--------SLPDGAILAWN---FIASNGMTGEGHHVRDTYKALELQPAGLEFSV 750 Agrobacterium tum... 15889832 688 dLFG------------AFFDTTYAYr-------fGPPSHDVTIARlrdIATGHVIADAFHFPLGRKKALHAANLQVAISE 748 Agrobacterium tum... 15965678 703 ---DR-----------ASTLVTVAAk--------DIPPDTLLFWS---FEASNGATGEGHYAHGTYKALDLVPSGLTIEA 757 Sinorhizobium mel... 15900551 844 l--------------eAIARDESGK---------EIARDKITTAG---KPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQ 897 Streptococcus pne... 15899743 -------------------------------------------------------------------------------- Sulfolobus solfat... 15643820 -------------------------------------------------------------------------------- Thermotoga maritima 15644372 678 ----------------ADGVSLVDRv--------ELPDDLFFFVE----AEVDGVKYRNYRVFRKWRDLELPDPEISLED 729 Thermotoga maritima 15837448 751 -LSSLqv--------aHYSDTQLLGh--------TDPTHTIAVFE---LLDGNTLLSRQTLLFDAAKHLKLPQSYIHSTW 810 Xylella fastidios... 16130971 760 -QVNGe---------sLLTREPKINffkp--midNHKQEYEGLWQpnhLQIMQEHLRDFAVEQSDGEVLIISRTVIAPPV 827 Escherichia coli K12 15888848 696 ---DK-----------AATLTDIDMd--------SLPDGAILAWN---FIASNGMTGEGHHVRDTYKALELQPAGLEFSV 750 Agrobacterium tum... 15889832 688 dLFG------------AFFDTTYAYr-------fGPPSHDVTIARlrdIATGHVIADAFHFPLGRKKALHAANLQVAISE 748 Agrobacterium tum... 15965678 703 ---DR-----------ASTLVTVAAk--------DIPPDTLLFWS---FEASNGATGEGHYAHGTYKALDLVPSGLTIEA 757 Sinorhizobium mel... 15900551 844 l--------------eAIARDESGK---------EIARDKITTAG---KPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQ 897 Streptococcus pne... 15899743 -------------------------------------------------------------------------------- Sulfolobus solfat... 15643820 -------------------------------------------------------------------------------- Thermotoga maritima 15644372 678 ----------------ADGVSLVDRv--------ELPDDLFFFVE----AEVDGVKYRNYRVFRKWRDLELPDPEISLED 729 Thermotoga maritima 15837448 751 -LSSLqv--------aHYSDTQLLGh--------TDPTHTIAVFE---LLDGNTLLSRQTLLFDAAKHLKLPQSYIHSTW 810 Xylella fastidios... 16130971 760 -QVNGe---------sLLTREPKINffkp--midNHKQEYEGLWQpnhLQIMQEHLRDFAVEQSDGEVLIISRTVIAPPV 827 Escherichia coli K12
15675473 927 LTSqqEIGQSCLKTTQFLSVLENKDTQQKagkaSTPHILItSYQHYLSLPLQVCsQAFDFKKGDDIFLPQWLQVKDA 1003 Streptococcus pyogen... 15888848 751 GPLk-NGQFEIDVTAAGLALFIMLEADQPg---RYSDNLFdLAAGETRRIIFTP---KGAGPQPHFRIFDLHTCQSS 820 Agrobacterium tumefa... 15889832 749 TNG----HWSLEIGTDRLAQSVHITAEGY----RACESWFhLGPGEARKIGLLPeTATTEAPPSGEVVSLGSSRRFS 817 Agrobacterium tumefa... 15965678 758 VPRp-DGSFDVAVTAAGLALHVMIEADVEg---RYSDNAFdLTAGETKSIRFTPrIALDAGASPRFSAYDLESCQGK 830 Sinorhizobium meliloti 15900551 898 GNVvpTANNLVRFQLHGQGQLVGVDNGEQa---SRERYKAqADGSWIRKAFNGKgVAIVKSTEQAGKFTLTAhsdll 971 Streptococcus pneumo... 15899743 ----------------------------------------------------------------------------- Sulfolobus solfataricus 15643820 ----------------------------------------------------------------------------- Thermotoga maritima 15644372 730 MGE------LIELTAQRPAFGVKILSDEVp----E-DDFLfLEPGRSITLKKPDgVRGVKSLFDYLR---------- 785 Thermotoga maritima 15837448 811 KTE--HGMFLLTLTSPTLARNVWLSFGDId--aQLSDNAFdLLPGEPLTIHIRS-SAPLTQLQHALHIRDLAATLAG 882 Xylella fastidiosa 9a5c 16130971 828 FDFg-MRCTYIWRIAADGQVNVALSGERYg---DYPHIIPcIGFTMGINGEYDQvAYYGRGPGENYADSQQANIIDI 900 Escherichia coli K12 15888848 751 GPLk-NGQFEIDVTAAGLALFIMLEADQPg---RYSDNLFdLAAGETRRIIFTP---KGAGPQPHFRIFDLHTCQSS 820 Agrobacterium tumefa... 15889832 749 TNG----HWSLEIGTDRLAQSVHITAEGY----RACESWFhLGPGEARKIGLLPeTATTEAPPSGEVVSLGSSRRFS 817 Agrobacterium tumefa... 15965678 758 VPRp-DGSFDVAVTAAGLALHVMIEADVEg---RYSDNAFdLTAGETKSIRFTPrIALDAGASPRFSAYDLESCQGK 830 Sinorhizobium meliloti 15900551 898 GNVvpTANNLVRFQLHGQGQLVGVDNGEQa---SRERYKAqADGSWIRKAFNGKgVAIVKSTEQAGKFTLTAhsdll 971 Streptococcus pneumo... 15899743 ----------------------------------------------------------------------------- Sulfolobus solfataricus 15643820 ----------------------------------------------------------------------------- Thermotoga maritima 15644372 730 MGE------LIELTAQRPAFGVKILSDEVp----E-DDFLfLEPGRSITLKKPDgVRGVKSLFDYLR---------- 785 Thermotoga maritima 15837448 811 KTE--HGMFLLTLTSPTLARNVWLSFGDId--aQLSDNAFdLLPGEPLTIHIRS-SAPLTQLQHALHIRDLAATLAG 882 Xylella fastidiosa 9a5c 16130971 828 FDFg-MRCTYIWRIAADGQVNVALSGERYg---DYPHIIPcIGFTMGINGEYDQvAYYGRGPGENYADSQQANIIDI 900 Escherichia coli K12
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",