Conserved Protein Domain Family
ERG3

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COG3000: ERG3 (this model, PSSM-Id:225546 is obsolete and has been replaced by 442238)
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
Statistics
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PSSM-Id: 225546
Aligned: 32 rows
Threshold Bit Score: 105.228
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
17548951  88 NRRRLNALAFAFVLAAVALGGSRVQVgnfpdhtpyigLDWFILDLlgstviFvlLEKLFPLYKKQPVFRpeWQTDMVHFA 167 Ralstonia solanacearum
19114047  16 iynavypLARDNIVRQSISLFFLTWF-----------GGMFLYLTfas-lsYqfVFDKSLMDHPKFLKN--QVFMEVL-T 80  fission yeast
19115335  60 eilksakvplknkefsdlvdqnigvgygnefivkptdldkdfeknhfldlkkpllpqilfgnikkdvyldqvhrprhyrg 139 fission yeast
19113815  29 FVEQLWLAYYKWFDNDVVATGLMSFL-----------LHELIYFGrcipwmIidAMPYFRRWKIQPKKV--PTLAEQWEC 95  fission yeast
19113281   7 MLTTWNPVTVSLVSPVIIYWVASAFFg-------------FLHYIelpvfeKyrIHPPEEIARRNRVPQmaVVKAVLFQQ 73  fission yeast
730850    34 INLRPKESLLPEMSDGVLALVAPVVAyw-------alSGIFHVIDtfhlaeKyrIHPSEEVAKRNKASRmhVFLEVILQH 106 baker's yeast
1706683   35 FMEKYWAAWYSYMNNDVLATGLMFFL-----------LHEFMYFFrclpwfIidQIPYFRRWKLQPTKI--PSAKEQLYC 101 baker's yeast
416963    77 TTSFASLLPRSSILREFLSLWVIVTI-----------FGLLLYLFtas-lsYvfVFDKSIFNHPRYLKN--QMAMEIK-L 141 baker's yeast
2493967  122 fvkelpaeeklsiatdysndykkhkfldlnrpllmqilrsdfkkdfyvdqihrprhygkgsaplfgnflepltktawwvv 201 baker's yeast
13471789     --------------------------------------------------------------------------------     Mesorhizobium loti
17548951 168 VNHFIVGLVLLVVNFLIHRVFGWMVNAGFQQm----------------vQQIWF---VPQLLLCMLVADLMEYVTHRAYH 228 Ralstonia solanacearum
19114047  81 ALQNLPGMALLTVPWFLAELHGYSYLYDNISd----------------yGLKYF---LCSLPLFVMFSDFGIYWAHRFLH 141 fission yeast
19115335 140 sgsaplfgnflepltktpwymipliwvpcvtygflyactgipfsvaitffiiglftwtLVEYTMHRFLFHLDEYTPDHPI 219 fission yeast
19113815  96 TRLVLLSHFTVELPQIWLFDPMCATFGLSTSvp--------------fpPVTKM---IWQITLFFFLEDTWHYWAHRLFH 158 fission yeast
19113281  74 LCEVVVGIALAMFEGYPEPIDEAKQMLRYEAffsknlpallqvapfapkLAYNFivpAFQYFFAFFIIDSWQYFWHRYLH 153 fission yeast
730850   107 IIQTIVGLIFMHFEPIYMTGFEENAMWKLRAdlprii------pdaaiyYGYMYgmsALKIFAGFLFVDTWQYFLHRLMH 180 baker's yeast
1706683  102 LKSVLLSHFLVEAIPIWTFHPMCEKLGITVEvp--------------fpSLKTM---ALEIGLFFVLEDTWHYWAHRLFH 164 baker's yeast
416963   142 AVSAIPWMSMLTVPWFVMELNGHSKLYMKIDye--------------nhGVRKL---IIEYFTFIFFTDCGVYLAHRWLH 204 baker's yeast
2493967  202 pvawlpvvvyhmgvalknmnqlfacfLFCVG-------------------VFVW---TLIEYGLHRFLFHFDDWLPESNI 259 baker's yeast
13471789   1 -------MVYPLAIALLGVAGLIEAGEESAP--------------------DWI---GTVLICLGLWTLIEYVLHRFVLH 50  Mesorhizobium loti
17548951 229 EVPFLW-RFHAVHHSVKTMDWLAGSRQHILELIVTRVAVLGPLFVLG-----FDKSVVDTYIIIVGFQAVFNHANVHLPw 302 Ralstonia solanacearum
19114047 142 HRYVYP-RLHKLHHKWIICTPYASHAFKSADGFLQSLPYHLFPFFFP-----LHKLTYLALFTFVNFWSIMIHDG----- 210 fission yeast
19115335 220 FLTMHF-AFHGCHHFLPADKYRLVMPPALFLIFATPWYHFIQLVLPH-----YIGVAGFSGAILGYVFYDLTHYFLHHRr 293 fission yeast
19113815 159 YGIFYR-FIHKVHHRYSAPFGLSAEYAHPLEIILLGAGTVFVPLMWCyfthdLHLVTMYIWITLRLFQAVDSHAGYDFP- 236 fission yeast
19113281 154 YNKKLYnMIHAHHHRLQVPYAMGALYNHPFEGLILDTFGAGVAYLAAg----LSPQQAVIFFTLSTLKTVDDHCGYVFPy 229 fission yeast
730850   181 MNKTLYkWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTh----LTHREQIILFTFATMKTVDDHCGYALPl 256 baker's yeast
1706683  165 YGVFYK-YIHKQHHRYAAPFGLSAEYAHPAETLSLGFGTVGMPILYVmytgkLHLFTLCVWITLRLFQAVDSHSGYDFP- 242 baker's yeast
416963   205 WPRVYR-ALHKPHHKWLVCTPFASHSFHPVDGFLQSISYHIYPLILP-----LHKVSYLILFTFVNFWTVMIHDG----- 273 baker's yeast
2493967  260 AFATHF-LLHGCHHYLPMDKYRLVMPPTLFVILCAPFYKLVFALLPL-----YWAYAGFAGGLFGYVCYDECHFFLHHSk 333 baker's yeast
13471789  51 HVPYIR-DLHDRHHVDERSPVGTPTWLSLGVHALIALPVWVLSDFAT-----ASAVGCGLMLGYLWYISVHHMIHH---- 120 Mesorhizobium loti
17548951 303 GPLKYI---FVTPDFHHWHHSSENeaIDKNYA-AHFAFIDYLFGT-AVKSKKAFPEKYGVVGDYMPDgFVNQQRFPFRRT 377 Ralstonia solanacearum
19114047 211 KYISNNpiiNGAA-HHNGHHIYF---N-YNYG-QFTTLFDRLGNS-FRAPDEAWFDKDLRQNEDVLR-VELMEYEAIRNE 282 fission yeast
19115335 294 MPNAYLt---DLKTWHLDHHYKD---YKSAYG-ITSWFWDRVFGT-EGPLFNE-QGKISTKAK----------------- 347 fission yeast
19113815 237 WSLNKFlpiWAGADHHDYHHMAF---K-DNFS-SSFRWWDAVLK--------TDQNY-HQFKARRLA-AKYEAESKKAK- 300 fission yeast
19113281 230 DPLQMFf--aNNARYHDLHHQPYG--FQKNFSqPFFTFWDHVLGT-YMPPKSETPYEKKQKAKNAKKvN----------- 293 fission yeast
730850   257 DPFQWLf--pNNAVYHDIHHQQFG--IKTNFAqPFFTFWDNLFQTnFKGFEEYQKKQRRVTIDKYKEfLQERELEKKEKL 332 baker's yeast
1706683  243 WSLNKImpfWAGAEHHDLHHHYF---I-GNYA-SSFRWWDYCLD--------TESGP-EAKASREER-MKKRAENNAQKK 307 baker's yeast
416963   274 QYLSNNpavNGTA-CHTVHHLYF---N-YNYG-QFTTLWDRLGGS-YRRPDDSLFDPKLRDAKETWD-AQVKEVEHFIKE 345 baker's yeast
2493967  334 LP-PFMr---KLKKYHLEHHYKN---YQLGFG-VTSWFWDEVFGT-YLGPDAP-LSKMKYE------------------- 384 baker's yeast
13471789 121 WHPAHPsylYTLKRRHAVHHHID---DSANFG-VTSLFWDRVFGT-ARL------------------------------- 164 Mesorhizobium loti
17548951 378 PTHPA 382 Ralstonia solanacearum
19114047 283 VEGDD 287 fission yeast
19115335     -----     fission yeast
19113815     -----     fission yeast
19113281     -----     fission yeast
730850   333 KNFKA 337 baker's yeast
1706683  308 TN--- 309 baker's yeast
416963   346 VEGDD 350 baker's yeast
2493967      -----     baker's yeast
13471789     -----     Mesorhizobium loti
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