7674472 1 MSRIDYRSIGLKVGLEIHQQLDTREKLFCSCPAELGE-EE-HDEFVRQLRPTRSELGDVDPAALFEWRKGRLYIYQAPLN 78 Aeropyrum pernix 7674429 1 --MMDYKKLGLKVGIEIHQQLDTKHKLFCLCPTLTREvEEsNFEFFRYLRLKRSEIGEEDRAAKEEVERSRRFIYKYY-D 77 Archaeoglobus fulgidus 20091686 1 MEKYDYSELGLKAGLEIHQQLDSKEKLFCRCPTLIRDiGDsDFEFFRYLRATESEMGEKDRAAVEQTKIRRKYIYKAY-D 79 Methanosarcina acet... 2499483 1 -MEINYEKVGLKVGLEIHQQLNTKRKLFCHCPTILRD-DEpDGEIVRVLRPSLSEMGEVDRAALIEARKGKKFIYQFYND 78 Methanocaldococcus ... 20093569 3 EEDLDWEEIGLRVGLEIHRQLDTSRKLFCRCTPELVEeVPkEPKVRRKLRPVQSEMGEFDPAALEEFKRDRTFYYLADGS 82 Methanopyrus kandle... 7674414 1 ---MDWEKVGLKMGLEIHQQLDTESKLFCPCRTELTD-SEpDHDIVRNLRPTQSELGKFDRAAFEEAMRKLHFHYENYHE 76 Methanothermobacter... 14520907 5 TDKFNYEELGLKVGLEIHRQLDTK-KLFSPVPSELSD--KvEFTFQRRLRPTMSELGEIDPAALEEFKKGRVYVYEGNYE 81 Pyrococcus abyssi 18313919 1 ---MDYKALGLKTGLEIHIQLNTQRKLFCHCPPVLRD-DEpHFRVERRLHISVSELGAVDPAVVWEVRKRRKYIYEGYRD 76 Pyrobaculum aerophilum 7674430 5 SDKFNYEELGLKVGLEIHRQLDTK-KLFSPVPTKFSD--EvDFTFQRRLRPTMSELGEVDPAALEEFKKGRVFIYEGNYQ 81 Pyrococcus horikoshii 15897817 1 MSELNYEELGLKVGLEIHQQLNTPHKLFCNCSTNLEE--EyKLTLERYLRPALSELGEVDVAALFEWKKGKKYVYRIPIT 78 Sulfolobus solfatar... 13541948 1 -----MTHRNIKIGLEIHFQLNTG-KLFCRCPVETSG-TE-KYRFERHLHVSESEMGRIDAAAKYESERSRTFEYVVT-D 71 Thermoplasma volcanium 16082011 1 --------MDTKIGLEVHFQLNTG-KLFCRCPVEQSS-GE-LMRFSRKLHISASELGNIDAAASYESMRSRSFQYVVT-D 68 Thermoplasma acidop... 15790381 1 MTEFDYDELGLVAGLEIHQQLDTATKLFCACPTTRREpAEaDRTFTRYLHPTRSELGEIDEAALEESRVEREFEYLAY-D 79 Halobacterium sp. N... 7674429 1 --MMDYKKLGLKVGIEIHQQLDTKHKLFCLCPTLTREvEEsNFEFFRYLRLKRSEIGEEDRAAKEEVERSRRFIYKYY-D 77 Archaeoglobus fulgidus 20091686 1 MEKYDYSELGLKAGLEIHQQLDSKEKLFCRCPTLIRDiGDsDFEFFRYLRATESEMGEKDRAAVEQTKIRRKYIYKAY-D 79 Methanosarcina acet... 2499483 1 -MEINYEKVGLKVGLEIHQQLNTKRKLFCHCPTILRD-DEpDGEIVRVLRPSLSEMGEVDRAALIEARKGKKFIYQFYND 78 Methanocaldococcus ... 20093569 3 EEDLDWEEIGLRVGLEIHRQLDTSRKLFCRCTPELVEeVPkEPKVRRKLRPVQSEMGEFDPAALEEFKRDRTFYYLADGS 82 Methanopyrus kandle... 7674414 1 ---MDWEKVGLKMGLEIHQQLDTESKLFCPCRTELTD-SEpDHDIVRNLRPTQSELGKFDRAAFEEAMRKLHFHYENYHE 76 Methanothermobacter... 14520907 5 TDKFNYEELGLKVGLEIHRQLDTK-KLFSPVPSELSD--KvEFTFQRRLRPTMSELGEIDPAALEEFKKGRVYVYEGNYE 81 Pyrococcus abyssi 18313919 1 ---MDYKALGLKTGLEIHIQLNTQRKLFCHCPPVLRD-DEpHFRVERRLHISVSELGAVDPAVVWEVRKRRKYIYEGYRD 76 Pyrobaculum aerophilum 7674430 5 SDKFNYEELGLKVGLEIHRQLDTK-KLFSPVPTKFSD--EvDFTFQRRLRPTMSELGEVDPAALEEFKKGRVFIYEGNYQ 81 Pyrococcus horikoshii 15897817 1 MSELNYEELGLKVGLEIHQQLNTPHKLFCNCSTNLEE--EyKLTLERYLRPALSELGEVDVAALFEWKKGKKYVYRIPIT 78 Sulfolobus solfatar... 13541948 1 -----MTHRNIKIGLEIHFQLNTG-KLFCRCPVETSG-TE-KYRFERHLHVSESEMGRIDAAAKYESERSRTFEYVVT-D 71 Thermoplasma volcanium 16082011 1 --------MDTKIGLEVHFQLNTG-KLFCRCPVEQSS-GE-LMRFSRKLHISASELGNIDAAASYESMRSRSFQYVVT-D 68 Thermoplasma acidop... 15790381 1 MTEFDYDELGLVAGLEIHQQLDTATKLFCACPTTRREpAEaDRTFTRYLHPTRSELGEIDEAALEESRVEREFEYLAY-D 79 Halobacterium sp. N...
7674472 79 HSCLVEADEEPPHPINREAVAVAVAVAKALGSAIVDEVHVMRKTVIDGSNTSGFQRTAIVALGGSIRVGSKEVPIETIVI 158 Aeropyrum pernix 7674429 78 TTCLVEADEEPPREVNREALLIAIQVAKMLNMEVVDEVHVMRKIVIDGSNTTGFQRTALVAFGGFLEVDGKRVGVATLCL 157 Archaeoglobus fulgidus 20091686 80 TTCLIENDEEPPRELNKEALDISLGVSKLFNMKPVDQMHVMRKIVVDGSNTSGFQRTAFLASDGYIETSEGRCGIDSLCV 159 Methanosarcina acet... 2499483 79 TTCLVELDEEPPHPPSEEALRIALEVALLMNMNVVDVAYTMRKIVIDGSNTSGFQRTIFLARDGYIETSEGKVGITSLCL 158 Methanocaldococcus ... 20093569 83 FSCLVELDEEPPHEPCSEALDVAIKVTLLLGGSVVDEVHVMRKMVIDGSNTTGFQRTMLVGFGGEVPTSEGPVRISTVCL 162 Methanopyrus kandle... 7674414 77 ETCLVEADEEPPHPLNPEALEIAVTIALLLNMRVVDEFHTMRKQVIDGSNTGGFQRTGLVATDGHLETPQGTVKIENLCL 156 Methanothermobacter... 14520907 82 LTDLVYMDEEPPRGPDREALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGAVGIPTICL 161 Pyrococcus abyssi 18313919 77 TTCLVELDEEPPHLPDEEALVTAVAVAKMFNAKLFDEIYVMRKTVVDGSNVSGFQRTMLIAYGGRAKILGYDIGVETIAL 156 Pyrobaculum aerophilum 7674430 82 LTDLVYMDEEPPRGPDKEALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGTVGIPTICL 161 Pyrococcus horikoshii 15897817 79 TSCLVEADEEPPHAINEEALKIALAIAMALNSNIVDEIYVMRKIVIDGSNTTGFQRTAIIALGGMLKDEE--VSIQSIAV 156 Sulfolobus solfatar... 13541948 72 NSCLVECDEDPPKMPNEDAIATAISVARALNCDILDYITYMRKIVIDGSNTSGFQRTAIIGINGYIETSKGKVRISTVCL 151 Thermoplasma volcanium 16082011 69 NSCLVEMDEEPPKTPDERAIATAISVSKALNCDIVDHITYMRKIVIDGSNTTGFQRTAIVGINGHIETSKGPVRISTVCL 148 Thermoplasma acidop... 15790381 80 TTCLVEEDDEPPHRLDEDALAAALEIGHLLGMDAVDRAHVMRKVVIDGSNTGGFQRSTMVAEGGAIDTSEGPVGIEDLML 159 Halobacterium sp. N... 7674429 78 TTCLVEADEEPPREVNREALLIAIQVAKMLNMEVVDEVHVMRKIVIDGSNTTGFQRTALVAFGGFLEVDGKRVGVATLCL 157 Archaeoglobus fulgidus 20091686 80 TTCLIENDEEPPRELNKEALDISLGVSKLFNMKPVDQMHVMRKIVVDGSNTSGFQRTAFLASDGYIETSEGRCGIDSLCV 159 Methanosarcina acet... 2499483 79 TTCLVELDEEPPHPPSEEALRIALEVALLMNMNVVDVAYTMRKIVIDGSNTSGFQRTIFLARDGYIETSEGKVGITSLCL 158 Methanocaldococcus ... 20093569 83 FSCLVELDEEPPHEPCSEALDVAIKVTLLLGGSVVDEVHVMRKMVIDGSNTTGFQRTMLVGFGGEVPTSEGPVRISTVCL 162 Methanopyrus kandle... 7674414 77 ETCLVEADEEPPHPLNPEALEIAVTIALLLNMRVVDEFHTMRKQVIDGSNTGGFQRTGLVATDGHLETPQGTVKIENLCL 156 Methanothermobacter... 14520907 82 LTDLVYMDEEPPRGPDREALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGAVGIPTICL 161 Pyrococcus abyssi 18313919 77 TTCLVELDEEPPHLPDEEALVTAVAVAKMFNAKLFDEIYVMRKTVVDGSNVSGFQRTMLIAYGGRAKILGYDIGVETIAL 156 Pyrobaculum aerophilum 7674430 82 LTDLVYMDEEPPRGPDKEALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGTVGIPTICL 161 Pyrococcus horikoshii 15897817 79 TSCLVEADEEPPHAINEEALKIALAIAMALNSNIVDEIYVMRKIVIDGSNTTGFQRTAIIALGGMLKDEE--VSIQSIAV 156 Sulfolobus solfatar... 13541948 72 NSCLVECDEDPPKMPNEDAIATAISVARALNCDILDYITYMRKIVIDGSNTSGFQRTAIIGINGYIETSKGKVRISTVCL 151 Thermoplasma volcanium 16082011 69 NSCLVEMDEEPPKTPDERAIATAISVSKALNCDIVDHITYMRKIVIDGSNTTGFQRTAIVGINGHIETSKGPVRISTVCL 148 Thermoplasma acidop... 15790381 80 TTCLVEEDDEPPHRLDEDALAAALEIGHLLGMDAVDRAHVMRKVVIDGSNTGGFQRSTMVAEGGAIDTSEGPVGIEDLML 159 Halobacterium sp. N...
7674472 159 EEDAARKVGEKGR--YVVYRLDRLGIPLIEIATAPVIESPGEAREVALAIGTMLRLTGKVKRGLGTIRQDLNVSIRGGAK 236 Aeropyrum pernix 7674429 158 EEEACRKVEDGEG--YAVYSLDRLGIPLVEIGTEPDIDSPEMAKKVAARLGMILRSTGKVKRGLGTIRQDVNISIRDGAR 235 Archaeoglobus fulgidus 20091686 160 EEEAAQKIEEKGD--SIVYSLDRLGIPLVEIATAPDIRSPRHAREVAEYIGMVLRSTGKVKRGLGTIRQDVNISIARGER 237 Methanosarcina acet... 2499483 159 EEDAARKIEDRGD--AVVYNLDRLGIPLVEISTAPDIKTPKMAKEAARRIGEILRATGKVKRGLGTIRQDINISIKDGAR 236 Methanocaldococcus ... 20093569 163 EEDAARKVKGRDQdlEVDYCLDRLGIPLIEVSTEPDIRTPEQAREAAERIGEAIKAVGGVKSGIGTVRQDVNVSIEGGAV 242 Methanopyrus kandle... 7674414 157 EEDAARRIRETGD--GVVFRLDRLGIPLVEITTDPSMSDPQQLREVAYQIGQILRST-RVKRGLGTIRQDLNISIRDGAR 233 Methanothermobacter... 14520907 162 EEDAARIIERKDK--EVIYRLDRLGIPLIEISTTPDIHHPEQAKVVAKFIGDALRATKKVKRGLGTIRQDLNVSIKGGAR 239 Pyrococcus abyssi 18313919 157 EEDAARKISEEGK--AMVYRLDRLGIPLIEIATEPMAYTPQEVEEVAWIIGYSVKITGRAKRGVGTVRQDVNVSIAGGAK 234 Pyrobaculum aerophilum 7674430 162 EEDAARIIERKEK--EVIYRLDRLGVPLVEISTTPDIHHPEQAKVVAKFIGDALRATRKVKRGLGTIRQDLNVSIKGGAR 239 Pyrococcus horikoshii 15897817 157 EEDAARKIDEGTD--QVTYSLDRLGIPLIEISTGPDIRSPEQAERVALKIGQLLRMTGKVKRGIGTIRQDLNISIKGGTK 234 Sulfolobus solfatar... 13541948 152 EEDAARKIEEKEG--TVVYSLDRLGIPLIEISTEPDIIDEEHAVEVAKKIGYYVISTGKSRKAPDSVRQDVNFSMGFG-R 228 Thermoplasma volcanium 16082011 149 EEDAARKIEEIGN--TVVYSLDRLGIPLIEISTEPDIVDEDHAVEVARSIGYIVISTGNARHAVDAVRQDVNFSMGYG-R 225 Thermoplasma acidop... 15790381 160 EEESAQRIEDRED--GVLYSLDRLGIPLVEIGTKPDISSPAQAREAAERIGMLLRSTGKVKRGLGTIRQDVNVSIADGAR 237 Halobacterium sp. N... 7674429 158 EEEACRKVEDGEG--YAVYSLDRLGIPLVEIGTEPDIDSPEMAKKVAARLGMILRSTGKVKRGLGTIRQDVNISIRDGAR 235 Archaeoglobus fulgidus 20091686 160 EEEAAQKIEEKGD--SIVYSLDRLGIPLVEIATAPDIRSPRHAREVAEYIGMVLRSTGKVKRGLGTIRQDVNISIARGER 237 Methanosarcina acet... 2499483 159 EEDAARKIEDRGD--AVVYNLDRLGIPLVEISTAPDIKTPKMAKEAARRIGEILRATGKVKRGLGTIRQDINISIKDGAR 236 Methanocaldococcus ... 20093569 163 EEDAARKVKGRDQdlEVDYCLDRLGIPLIEVSTEPDIRTPEQAREAAERIGEAIKAVGGVKSGIGTVRQDVNVSIEGGAV 242 Methanopyrus kandle... 7674414 157 EEDAARRIRETGD--GVVFRLDRLGIPLVEITTDPSMSDPQQLREVAYQIGQILRST-RVKRGLGTIRQDLNISIRDGAR 233 Methanothermobacter... 14520907 162 EEDAARIIERKDK--EVIYRLDRLGIPLIEISTTPDIHHPEQAKVVAKFIGDALRATKKVKRGLGTIRQDLNVSIKGGAR 239 Pyrococcus abyssi 18313919 157 EEDAARKISEEGK--AMVYRLDRLGIPLIEIATEPMAYTPQEVEEVAWIIGYSVKITGRAKRGVGTVRQDVNVSIAGGAK 234 Pyrobaculum aerophilum 7674430 162 EEDAARIIERKEK--EVIYRLDRLGVPLVEISTTPDIHHPEQAKVVAKFIGDALRATRKVKRGLGTIRQDLNVSIKGGAR 239 Pyrococcus horikoshii 15897817 157 EEDAARKIDEGTD--QVTYSLDRLGIPLIEISTGPDIRSPEQAERVALKIGQLLRMTGKVKRGIGTIRQDLNISIKGGTK 234 Sulfolobus solfatar... 13541948 152 EEDAARKIEEKEG--TVVYSLDRLGIPLIEISTEPDIIDEEHAVEVAKKIGYYVISTGKSRKAPDSVRQDVNFSMGFG-R 228 Thermoplasma volcanium 16082011 149 EEDAARKIEEIGN--TVVYSLDRLGIPLIEISTEPDIVDEDHAVEVARSIGYIVISTGNARHAVDAVRQDVNFSMGYG-R 225 Thermoplasma acidop... 15790381 160 EEESAQRIEDRED--GVLYSLDRLGIPLVEIGTKPDISSPAQAREAAERIGMLLRSTGKVKRGLGTIRQDVNVSIADGAR 237 Halobacterium sp. N...
7674472 237 TEIKGVQRLELIPRVIEYEVLRQLSLLRIRDMLRERGvsrEELENVEPV-DVSSLLAGSKSRVIKKVLSS-GGKVIAVKL 314 Aeropyrum pernix 7674429 236 VEIKGVQELDILDKIVEYEVLRQVNLLKIREELKQR----GARVEEKVF-DVTDVFSNTKSKIIRNKT------VKAILL 304 Archaeoglobus fulgidus 20091686 238 VEIKGVQALDLIEDIVRREVERQLNLLFIRQELLER----KAFVCEEIY-DVTGLFMDTKSKVLQKGVKK-GS-ILAALL 310 Methanosarcina acet... 2499483 237 IEVKGVQDLDLIEKVVENEVIRQLNLLKIRDELRER----NAEVVEKIF-DVTEIFKDCKSKIIQNALKKkNGKVKAVLL 311 Methanocaldococcus ... 20093569 243 QEIKGVQDLNLIPKVVKYEALRQANLLRIRDELRERGvseTDLIDCEPM-DVTDVFEDTDSEVIRRELER-GGVVYALLL 320 Methanopyrus kandle... 7674414 234 VEVKGVQDLDLIPEIVEREVKRQLSLVEIRDTLQER----GAVVEDKIF-DVSEVFADTESRIISSAES-----VLAVKL 303 Methanothermobacter... 14520907 240 IEIKGVQELDMIPIIIEREVERQLNLLKIRDELRKRGv-kPKDIKEEFY-DVTDIFENTKSKIIARVIKK-GGKVLAIKL 316 Pyrococcus abyssi 18313919 235 TEIKGVPDLSLIPKVIEYEAVRQVNLLKIAEELKRRGvgrVELS---VA-DVTAAFANTKSRLVRKVLDS-GGRVLALKT 309 Pyrobaculum aerophilum 7674430 240 IEIKGVQELDMIPLIIEREVERQLNLLKIRDELQRRGv-rPEDIKEEFY-DVTDVFTNTKSKIIARAIKK-GGKVLAIKL 316 Pyrococcus horikoshii 15897817 235 IEIKGVQKLELIPDIVRYEAIRQFNLLKIKEELYRRGltkELVLSNFVVkDVTELFKNTNSKIIKNGIEK-GGLVYGIRA 313 Sulfolobus solfatar... 13541948 229 VEIKGVSKLSQIKEVLKYEIQRQDMLKKASDLIKLRG---GFDRSRFYFiDVTDLLVNTSSKVVNSGLKT--GRAYAALC 303 Thermoplasma volcanium 16082011 226 VEIKGVSKLTQIRDVIRYEKERQENLRAAVDLIKSRG---GLDRVSFNLkDVSDLFAGTKSKIIRSGIES--GGVYAGIL 300 Thermoplasma acidop... 15790381 238 VEMKGVQSLDDIDDLVREEVRRQVELLDIVDELDAR----DAAVGKPR--DVTDVFADTESGVIRGALDD-GGEVHAVPL 310 Halobacterium sp. N... 7674429 236 VEIKGVQELDILDKIVEYEVLRQVNLLKIREELKQR----GARVEEKVF-DVTDVFSNTKSKIIRNKT------VKAILL 304 Archaeoglobus fulgidus 20091686 238 VEIKGVQALDLIEDIVRREVERQLNLLFIRQELLER----KAFVCEEIY-DVTGLFMDTKSKVLQKGVKK-GS-ILAALL 310 Methanosarcina acet... 2499483 237 IEVKGVQDLDLIEKVVENEVIRQLNLLKIRDELRER----NAEVVEKIF-DVTEIFKDCKSKIIQNALKKkNGKVKAVLL 311 Methanocaldococcus ... 20093569 243 QEIKGVQDLNLIPKVVKYEALRQANLLRIRDELRERGvseTDLIDCEPM-DVTDVFEDTDSEVIRRELER-GGVVYALLL 320 Methanopyrus kandle... 7674414 234 VEVKGVQDLDLIPEIVEREVKRQLSLVEIRDTLQER----GAVVEDKIF-DVSEVFADTESRIISSAES-----VLAVKL 303 Methanothermobacter... 14520907 240 IEIKGVQELDMIPIIIEREVERQLNLLKIRDELRKRGv-kPKDIKEEFY-DVTDIFENTKSKIIARVIKK-GGKVLAIKL 316 Pyrococcus abyssi 18313919 235 TEIKGVPDLSLIPKVIEYEAVRQVNLLKIAEELKRRGvgrVELS---VA-DVTAAFANTKSRLVRKVLDS-GGRVLALKT 309 Pyrobaculum aerophilum 7674430 240 IEIKGVQELDMIPLIIEREVERQLNLLKIRDELQRRGv-rPEDIKEEFY-DVTDVFTNTKSKIIARAIKK-GGKVLAIKL 316 Pyrococcus horikoshii 15897817 235 IEIKGVQKLELIPDIVRYEAIRQFNLLKIKEELYRRGltkELVLSNFVVkDVTELFKNTNSKIIKNGIEK-GGLVYGIRA 313 Sulfolobus solfatar... 13541948 229 VEIKGVSKLSQIKEVLKYEIQRQDMLKKASDLIKLRG---GFDRSRFYFiDVTDLLVNTSSKVVNSGLKT--GRAYAALC 303 Thermoplasma volcanium 16082011 226 VEIKGVSKLTQIRDVIRYEKERQENLRAAVDLIKSRG---GLDRVSFNLkDVSDLFAGTKSKIIRSGIES--GGVYAGIL 300 Thermoplasma acidop... 15790381 238 VEMKGVQSLDDIDDLVREEVRRQVELLDIVDELDAR----DAAVGKPR--DVTDVFADTESGVIRGALDD-GGEVHAVPL 310 Halobacterium sp. N...
7674472 315 PRMKGIIGMEIMPG-RRFGTELADYARFWgGVGGIIHSDELPGYGITGDEVEKIYEAVGGDPgVDAFALVADKP-SNALR 392 Aeropyrum pernix 7674429 305 RGFGGIVGREIQPG-RRLGTEFADIAKTY-GLGGVFHTDELPAYGISEEEVSRLRDAVGAED-GDAVVMAAGDA-VRVER 380 Archaeoglobus fulgidus 20091686 311 KKFNRLVGKEVQPG-RRLGTEFSDRAKTA-GVGGLFHTDELPNYGITEKEVQAVKDAIGAGP-EDAFVMVADEP-EKARL 386 Methanosarcina acet... 2499483 312 KGFAGLVGKEIQPG-RRLGTEFSDRAKVIaGVGGLFHTDELPKYGITEEEVKKLKEFVNAEE-NDAVIIVADEE-SKVDR 388 Methanocaldococcus ... 20093569 321 PGFEGILGWELCPG-RRFGTELADYARRR-GVSGLFHSDELPKYGISEEEVEAVRQRLGAED-GDGFVLIAGPE-DRVKS 396 Methanopyrus kandle... 7674414 304 RGFDGLIGVEIQPG-RRLGTEMADYAKKR-GVSGIFHTDELPAYGITEEEVRGLRDAVGASQ-GDAVVMVAHER-VTAEN 379 Methanothermobacter... 14520907 317 PKFRGLIGREIQPG-RRLGTEFADRAKKY--VPGIFHIDELPNYGISQEEVNKVIERLNLSE-EDAFVLVAAEE-EKAKN 391 Pyrococcus abyssi 18313919 310 PGFQKLLGFEIQPG-RRFGSELADYVRAWtELGGLLHSDELPGYGITAEEVREVANRLG----VESFILLMGVEeSELLE 384 Pyrobaculum aerophilum 7674430 317 PKFRGLIGREIQPG-RRLGTEFADRARKY--VPGIFHIDELPNYGITQEEVNEVIKRLGLGE-EDAFVLVAAEE-ERAKN 391 Pyrococcus horikoshii 15897817 314 YKLKGVLGWELIPKkRRFGTEIADYVRALaGLGGLFHSDELPNYGITEEEINKVREALNATT-EDALILIVGER-ERLDK 391 Sulfolobus solfatar... 13541948 304 TNLAG----TLKSGeYRLGKELADLVRAY-GLKGLLHSDELPGYGLKESDIQPIYDRLQKDE-LDGVIILLSPQ-EKIGI 376 Thermoplasma volcanium 16082011 301 KNMAG----TLKNGkLRMGKEIADLVRSY-GIKGVMHSDELPGYGLTQDEVEALYRYLGKGD-NDAVLLIAINQ-SRVKM 373 Thermoplasma acidop... 15790381 311 HGFDGLVGRELQAD-RRLGTEFSDHATRH-GAGGIFHTDELPAYGVTAAEVAALRDAVGAGE-DDAVAIVADDP-ETAAQ 386 Halobacterium sp. N... 7674429 305 RGFGGIVGREIQPG-RRLGTEFADIAKTY-GLGGVFHTDELPAYGISEEEVSRLRDAVGAED-GDAVVMAAGDA-VRVER 380 Archaeoglobus fulgidus 20091686 311 KKFNRLVGKEVQPG-RRLGTEFSDRAKTA-GVGGLFHTDELPNYGITEKEVQAVKDAIGAGP-EDAFVMVADEP-EKARL 386 Methanosarcina acet... 2499483 312 KGFAGLVGKEIQPG-RRLGTEFSDRAKVIaGVGGLFHTDELPKYGITEEEVKKLKEFVNAEE-NDAVIIVADEE-SKVDR 388 Methanocaldococcus ... 20093569 321 PGFEGILGWELCPG-RRFGTELADYARRR-GVSGLFHSDELPKYGISEEEVEAVRQRLGAED-GDGFVLIAGPE-DRVKS 396 Methanopyrus kandle... 7674414 304 RGFDGLIGVEIQPG-RRLGTEMADYAKKR-GVSGIFHTDELPAYGITEEEVRGLRDAVGASQ-GDAVVMVAHER-VTAEN 379 Methanothermobacter... 14520907 317 PKFRGLIGREIQPG-RRLGTEFADRAKKY--VPGIFHIDELPNYGISQEEVNKVIERLNLSE-EDAFVLVAAEE-EKAKN 391 Pyrococcus abyssi 18313919 310 PGFQKLLGFEIQPG-RRFGSELADYVRAWtELGGLLHSDELPGYGITAEEVREVANRLG----VESFILLMGVEeSELLE 384 Pyrobaculum aerophilum 7674430 317 PKFRGLIGREIQPG-RRLGTEFADRARKY--VPGIFHIDELPNYGITQEEVNEVIKRLGLGE-EDAFVLVAAEE-ERAKN 391 Pyrococcus horikoshii 15897817 314 YKLKGVLGWELIPKkRRFGTEIADYVRALaGLGGLFHSDELPNYGITEEEINKVREALNATT-EDALILIVGER-ERLDK 391 Sulfolobus solfatar... 13541948 304 TNLAG----TLKSGeYRLGKELADLVRAY-GLKGLLHSDELPGYGLKESDIQPIYDRLQKDE-LDGVIILLSPQ-EKIGI 376 Thermoplasma volcanium 16082011 301 KNMAG----TLKNGkLRMGKEIADLVRSY-GIKGVMHSDELPGYGLTQDEVEALYRYLGKGD-NDAVLLIAINQ-SRVKM 373 Thermoplasma acidop... 15790381 311 HGFDGLVGRELQAD-RRLGTEFSDHATRH-GAGGIFHTDELPAYGVTAAEVAALRDAVGAGE-DDAVAIVADDP-ETAAQ 386 Halobacterium sp. N...
7674472 393 AARAVLERVAAALEGVPEETRAALEDGTTRYLRPRPGSARMYPETDIPPLRIDENILSMAEPLVPEPPEVVAMRLKKEYG 472 Aeropyrum pernix 7674429 381 ALRRIIERAKHCLVGVPEETRKANEDGTTSYLRPLPGAARMYPETDVPPVVVTEEML---NVEIPELIEERARRYEK--L 455 Archaeoglobus fulgidus 20091686 387 AIEAVINRAKEAIEGIPEETRKALPDGNTAYMRPLPGAARMYPETDVPQIEISQEYFD--SIKPPELLTKRAKRFASESG 464 Methanosarcina acet... 2499483 389 ALEAVIERAKEALIGVPEETRRALEDGNTAYLRPLPGAARMYPETDIPPIIIKKEFIEEIRANLPELPEEKFERFKKEYK 468 Methanocaldococcus ... 20093569 397 AMEAVKDRAIMALKGVPAETRRARKDGTTEYMRPRPGAARMYPETDIPPVVIDEDRVKELAEELPEKPWERKERLAEEYG 476 Methanopyrus kandle... 7674414 380 ALREVIRRAEMAIQGVPEETRKALPDGNTQYLRPLPTSSRMYLETDIPLFRIEDDLLEGIRRNLPELPSEKKERIMRDYG 459 Methanothermobacter... 14520907 392 ALREVIKRAREAIEGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPLRIPDDLKKKIKENLPELPQAKVERYVKEYK 471 Pyrococcus abyssi 18313919 385 AAQVVVERLNMAPKGVPEETRAANPDGTTRFLRPRPGAARMYPETDLPPVKITFEIMKRAEEVAKINLDAKFKEL-ISLG 463 Pyrobaculum aerophilum 7674430 392 ALREVIKRAKEAIIGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPIRIPDELKRKIKENLPELPQVKVEKYVREYK 471 Pyrococcus horikoshii 15897817 392 AVEVIKDRILLAFDGIPKETRGALDDGTTKFLRPQPGSARMYPETDIPPRRIDEKLLEDAKKLVPESPESKMKRYIV-LG 470 Sulfolobus solfatar... 13541948 377 IEEEIANRIEKLISLDLSETRGPTED-STVFLRPMPGKDRMYPETDIPVIAVSKDILQKSDKIKSVGFEDLVSSIITKYG 455 Thermoplasma volcanium 16082011 374 IENSIFDRIQKIISMDLSETRGPAGE-ETVFLRPMPGKDRMYPETDIPVIKVDSKLMEMSSSIKPRTYAEVVQDLVDRYG 452 Thermoplasma acidop... 15790381 387 SIQAVAERAETAMAGVPEETRGANDDGTSKYLRPLPGAARMYPETDVPPVDPDPS-----AVETPELLTEKVERYQADFD 461 Halobacterium sp. N... 7674429 381 ALRRIIERAKHCLVGVPEETRKANEDGTTSYLRPLPGAARMYPETDVPPVVVTEEML---NVEIPELIEERARRYEK--L 455 Archaeoglobus fulgidus 20091686 387 AIEAVINRAKEAIEGIPEETRKALPDGNTAYMRPLPGAARMYPETDVPQIEISQEYFD--SIKPPELLTKRAKRFASESG 464 Methanosarcina acet... 2499483 389 ALEAVIERAKEALIGVPEETRRALEDGNTAYLRPLPGAARMYPETDIPPIIIKKEFIEEIRANLPELPEEKFERFKKEYK 468 Methanocaldococcus ... 20093569 397 AMEAVKDRAIMALKGVPAETRRARKDGTTEYMRPRPGAARMYPETDIPPVVIDEDRVKELAEELPEKPWERKERLAEEYG 476 Methanopyrus kandle... 7674414 380 ALREVIRRAEMAIQGVPEETRKALPDGNTQYLRPLPTSSRMYLETDIPLFRIEDDLLEGIRRNLPELPSEKKERIMRDYG 459 Methanothermobacter... 14520907 392 ALREVIKRAREAIEGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPLRIPDDLKKKIKENLPELPQAKVERYVKEYK 471 Pyrococcus abyssi 18313919 385 AAQVVVERLNMAPKGVPEETRAANPDGTTRFLRPRPGAARMYPETDLPPVKITFEIMKRAEEVAKINLDAKFKEL-ISLG 463 Pyrobaculum aerophilum 7674430 392 ALREVIKRAKEAIIGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPIRIPDELKRKIKENLPELPQVKVEKYVREYK 471 Pyrococcus horikoshii 15897817 392 AVEVIKDRILLAFDGIPKETRGALDDGTTKFLRPQPGSARMYPETDIPPRRIDEKLLEDAKKLVPESPESKMKRYIV-LG 470 Sulfolobus solfatar... 13541948 377 IEEEIANRIEKLISLDLSETRGPTED-STVFLRPMPGKDRMYPETDIPVIAVSKDILQKSDKIKSVGFEDLVSSIITKYG 455 Thermoplasma volcanium 16082011 374 IENSIFDRIQKIISMDLSETRGPAGE-ETVFLRPMPGKDRMYPETDIPVIKVDSKLMEMSSSIKPRTYAEVVQDLVDRYG 452 Thermoplasma acidop... 15790381 387 SIQAVAERAETAMAGVPEETRGANDDGTSKYLRPLPGAARMYPETDVPPVDPDPS-----AVETPELLTEKVERYQADFD 461 Halobacterium sp. N...
7674472 473 LSDQLAWEVIRDERYRLIVSLLEKyr--gTLEPSYVAGFFVVVLRGLEGEGVEVWKVDDAILEKILDMVAQGEIAREAAA 550 Aeropyrum pernix 7674429 456 LPKDLAWEIADSPYYRVFEEYSE------KLQPTVVARVLYLAPAALRREGVEIERLEERHYRLVLDMVLRGDIAKEGAE 529 Archaeoglobus fulgidus 20091686 465 LNKELAEKVAYSRYLPLFEILLETytkdaNVNSTLIARTLVGIVPEIRRNGVETDNLTDEHFKGLFAAISNQEIAKEAIQ 544 Methanosarcina acet... 2499483 469 LNDELAKKMVLSYYVDLFEDLCKkf---kNVKPVLIATTLEGTLKEIKREGYDIDKLEDRHLEETFKALSEGKIAKEGIV 545 Methanocaldococcus ... 20093569 477 LGEELVEQMFEHGVVDEFEEIVEe----tGVEPKVAAATLVNTIPRLEKDGYPVDNLTIDHVKEVLRLYAEGAIAKSGIE 552 Methanopyrus kandle... 7674414 460 LSEDLASQLVKRNLVDEFEALTef-----rVDTTVIASLLAYTLRELRREGHDVDGLGLDELRDAIKLLEVGKISKDALR 534 Methanothermobacter... 14520907 472 LDRSLAQTLVDDERDELFEELVSm-----GVKPSLAASILVVVLKGLRKE-VPIENVTDEHIREAFQLYLEGKIAKEAFE 545 Pyrococcus abyssi 18313919 464 LSKDLALQLIKSPHLEKFEEYLDKf---rSVPPQLIASILLNISKALAREGVEI---DGAKIESVLDALNRRVITKEAVE 537 Pyrobaculum aerophilum 7674430 472 LDRSLAQTLVDDERDELFEELVQm-----GVKPSLAASILVVVLKGLRKE-VPIENISDEHIKEAFSLYLEGKIAKEAFE 545 Pyrococcus horikoshii 15897817 471 LSEELAKEIIRDPRLDLFEELVNky--spRVPPVVIASTITNTLKYVKSKGGDISKINEEDIEELIKSIYESRISKDSIS 548 Sulfolobus solfatar... 13541948 456 ISKQVAESLASDMKIQELEELST------YLDPRESARVLTQIIPYLEKKYAKK--FDNNLIFVLVRLMSDRKFDRYQVE 527 Thermoplasma volcanium 16082011 453 ISKQNAEYIASEMVVDAFRNIAE------FVEAREAARILTQIVPDLERRTKKI--IDHDRIIELCRRSKDLHFDRYQLE 524 Thermoplasma acidop... 15790381 462 LDAGLAEQVAYGRRWQLFEQQVEa-----GVDATLAAQTLESTVTELRRDDVPVGRLTDAHFRGVLGLVADGDLAQEGVP 536 Halobacterium sp. N... 7674429 456 LPKDLAWEIADSPYYRVFEEYSE------KLQPTVVARVLYLAPAALRREGVEIERLEERHYRLVLDMVLRGDIAKEGAE 529 Archaeoglobus fulgidus 20091686 465 LNKELAEKVAYSRYLPLFEILLETytkdaNVNSTLIARTLVGIVPEIRRNGVETDNLTDEHFKGLFAAISNQEIAKEAIQ 544 Methanosarcina acet... 2499483 469 LNDELAKKMVLSYYVDLFEDLCKkf---kNVKPVLIATTLEGTLKEIKREGYDIDKLEDRHLEETFKALSEGKIAKEGIV 545 Methanocaldococcus ... 20093569 477 LGEELVEQMFEHGVVDEFEEIVEe----tGVEPKVAAATLVNTIPRLEKDGYPVDNLTIDHVKEVLRLYAEGAIAKSGIE 552 Methanopyrus kandle... 7674414 460 LSEDLASQLVKRNLVDEFEALTef-----rVDTTVIASLLAYTLRELRREGHDVDGLGLDELRDAIKLLEVGKISKDALR 534 Methanothermobacter... 14520907 472 LDRSLAQTLVDDERDELFEELVSm-----GVKPSLAASILVVVLKGLRKE-VPIENVTDEHIREAFQLYLEGKIAKEAFE 545 Pyrococcus abyssi 18313919 464 LSKDLALQLIKSPHLEKFEEYLDKf---rSVPPQLIASILLNISKALAREGVEI---DGAKIESVLDALNRRVITKEAVE 537 Pyrobaculum aerophilum 7674430 472 LDRSLAQTLVDDERDELFEELVQm-----GVKPSLAASILVVVLKGLRKE-VPIENISDEHIKEAFSLYLEGKIAKEAFE 545 Pyrococcus horikoshii 15897817 471 LSEELAKEIIRDPRLDLFEELVNky--spRVPPVVIASTITNTLKYVKSKGGDISKINEEDIEELIKSIYESRISKDSIS 548 Sulfolobus solfatar... 13541948 456 ISKQVAESLASDMKIQELEELST------YLDPRESARVLTQIIPYLEKKYAKK--FDNNLIFVLVRLMSDRKFDRYQVE 527 Thermoplasma volcanium 16082011 453 ISKQNAEYIASEMVVDAFRNIAE------FVEAREAARILTQIVPDLERRTKKI--IDHDRIIELCRRSKDLHFDRYQLE 524 Thermoplasma acidop... 15790381 462 LDAGLAEQVAYGRRWQLFEQQVEa-----GVDATLAAQTLESTVTELRRDDVPVGRLTDAHFRGVLGLVADGDLAQEGVP 536 Halobacterium sp. N...
7674472 551 ELVKYLANNPGSTVEEAVEKLGLRRLSREEVERIVDEIVGGLREEILKRGEKAVGLVMGRAMAKLRGRADGRLVSEIVSR 630 Aeropyrum pernix 7674429 530 EALKLLCQNPEMSAGQLKEKIG----AAEDIDGFIAKLIEEKADLIAERGEGAFKPLMGLVMKEFRGKVDGKVVAEKLKK 605 Archaeoglobus fulgidus 20091686 545 DLLTALAKEPELTVQEAISKLGLSAFDPEEVENFIKQMVMEKGDFIKDKGPSALGPLMGIVMKEYRGTVDGKILSHMLKK 624 Methanosarcina acet... 2499483 546 EVLKGFCEFPDKSIDEILEIKGLKGLSKEEVEKIIEGIIKEHLNVVKEKGEKAYGFLMGRCMAKLRGKADGKLVNDILRK 625 Methanocaldococcus ... 20093569 553 ELLGALAADPDSDPEELAEELGIVMASEEEIEEVVEEAIRRYEDKIRERGMAVMGKIMGEVMEVLRGRADGKRVSELVRE 632 Methanopyrus kandle... 7674414 535 DIVACMADEGLAAEDAARKLN-LLLLAEDEIESIIQEIVEGNLDMISERGMGAMGPLMGQAMGRLRGRADGKVVNRILRE 613 Methanothermobacter... 14520907 546 EIFKELARNPSKSAREVAEEKGLTLLSEEEVTRIIEEVIQQNIEVVKAKGMGAMGLIMGRVMAKVRGKADGKLVSQIVRR 625 Pyrococcus abyssi 18313919 538 EILRNMR--PGESAEEVARRLGLVRLPYEEVKKIVEEVS----RQTAK--EKIIGEVMRR----YRGRVD----IEDVKR 601 Pyrobaculum aerophilum 7674430 546 EIFKEIARNPNKTARQIAEEKGLTLLSEDEVRKIIDEVIEQNIEVVKNKGMGAMGLIMGRVMAKVRGKADGKLVSQIVKK 625 Pyrococcus horikoshii 15897817 549 EILVEYTTSKNVELKDIIRKY--EVLPIEELEKIIDDIINSNLDEIRKRKDKAVNLIMSKVMSKVKGRADGKIVLELIRS 626 Sulfolobus solfatar... 13541948 528 KALEILFS-ENKDPALIVSDERLIELTKDEICEIIDKLKKSGITITKA---NVVSVLKKN----TDRIFDPSMAIECLG- 598 Thermoplasma volcanium 16082011 525 MALEILY--ERDDVASVLGDSRLKELSREEIKSIIREILSSGRNATQN---SIIALIKEK----TERVFDPRVAMECFNE 595 Thermoplasma acidop... 15790381 537 ELLAALAEQPGSDPAVLAEELGLGSAAEDEVREAVVGVVERNSDQVAAEGMGAFSALMGECMGALRGKADGDLVSEVLRE 616 Halobacterium sp. N... 7674429 530 EALKLLCQNPEMSAGQLKEKIG----AAEDIDGFIAKLIEEKADLIAERGEGAFKPLMGLVMKEFRGKVDGKVVAEKLKK 605 Archaeoglobus fulgidus 20091686 545 DLLTALAKEPELTVQEAISKLGLSAFDPEEVENFIKQMVMEKGDFIKDKGPSALGPLMGIVMKEYRGTVDGKILSHMLKK 624 Methanosarcina acet... 2499483 546 EVLKGFCEFPDKSIDEILEIKGLKGLSKEEVEKIIEGIIKEHLNVVKEKGEKAYGFLMGRCMAKLRGKADGKLVNDILRK 625 Methanocaldococcus ... 20093569 553 ELLGALAADPDSDPEELAEELGIVMASEEEIEEVVEEAIRRYEDKIRERGMAVMGKIMGEVMEVLRGRADGKRVSELVRE 632 Methanopyrus kandle... 7674414 535 DIVACMADEGLAAEDAARKLN-LLLLAEDEIESIIQEIVEGNLDMISERGMGAMGPLMGQAMGRLRGRADGKVVNRILRE 613 Methanothermobacter... 14520907 546 EIFKELARNPSKSAREVAEEKGLTLLSEEEVTRIIEEVIQQNIEVVKAKGMGAMGLIMGRVMAKVRGKADGKLVSQIVRR 625 Pyrococcus abyssi 18313919 538 EILRNMR--PGESAEEVARRLGLVRLPYEEVKKIVEEVS----RQTAK--EKIIGEVMRR----YRGRVD----IEDVKR 601 Pyrobaculum aerophilum 7674430 546 EIFKEIARNPNKTARQIAEEKGLTLLSEDEVRKIIDEVIEQNIEVVKNKGMGAMGLIMGRVMAKVRGKADGKLVSQIVKK 625 Pyrococcus horikoshii 15897817 549 EILVEYTTSKNVELKDIIRKY--EVLPIEELEKIIDDIINSNLDEIRKRKDKAVNLIMSKVMSKVKGRADGKIVLELIRS 626 Sulfolobus solfatar... 13541948 528 KALEILFS-ENKDPALIVSDERLIELTKDEICEIIDKLKKSGITITKA---NVVSVLKKN----TDRIFDPSMAIECLG- 598 Thermoplasma volcanium 16082011 525 MALEILY--ERDDVASVLGDSRLKELSREEIKSIIREILSSGRNATQN---SIIALIKEK----TERVFDPRVAMECFNE 595 Thermoplasma acidop... 15790381 537 ELLAALAEQPGSDPAVLAEELGLGSAAEDEVREAVVGVVERNSDQVAAEGMGAFSALMGECMGALRGKADGDLVSEVLRE 616 Halobacterium sp. N...
7674472 631 KIREILDS 638 Aeropyrum pernix 7674429 606 ALKSALSQ 613 Archaeoglobus fulgidus 20091686 625 EIDNFIGQ 632 Methanosarcina acetivorans C2A 2499483 626 KLKEI--- 630 Methanocaldococcus jannaschii 20093569 633 RIREISGE 640 Methanopyrus kandleri AV19 7674414 614 KIQERL-- 619 Methanothermobacter thermautotrophicus 14520907 626 KLQEISGG 633 Pyrococcus abyssi 18313919 602 ALAEIAS- 608 Pyrobaculum aerophilum 7674430 626 RLQEIVGG 633 Pyrococcus horikoshii 15897817 627 RLKNVIE- 633 Sulfolobus solfataricus 13541948 -------- Thermoplasma volcanium 16082011 596 VKNKNNVF 603 Thermoplasma acidophilum 15790381 617 EIQQRS-- 622 Halobacterium sp. NRC-1 7674429 606 ALKSALSQ 613 Archaeoglobus fulgidus 20091686 625 EIDNFIGQ 632 Methanosarcina acetivorans C2A 2499483 626 KLKEI--- 630 Methanocaldococcus jannaschii 20093569 633 RIREISGE 640 Methanopyrus kandleri AV19 7674414 614 KIQERL-- 619 Methanothermobacter thermautotrophicus 14520907 626 KLQEISGG 633 Pyrococcus abyssi 18313919 602 ALAEIAS- 608 Pyrobaculum aerophilum 7674430 626 RLQEIVGG 633 Pyrococcus horikoshii 15897817 627 RLKNVIE- 633 Sulfolobus solfataricus 13541948 -------- Thermoplasma volcanium 16082011 596 VKNKNNVF 603 Thermoplasma acidophilum 15790381 617 EIQQRS-- 622 Halobacterium sp. NRC-1
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",