1CL2_A 1 MA--DKKLDTQLVNAGRSK-------------------KYTLGAVNSVIQRASSLVFDSVEAKKHATr------------ 47 Escherichia coli 16125673 1 -----MDEETRLIHTGSEP-------------------ARLGRTVNPPIQRGSTVLLPDAA-----Sl------------ 39 Caulobacter crescen... 15792713 1 -----------------------------------------------------MEKYRELRKT----------------- 10 Campylobacter jejuni 17546358 7 LP--PPFPATQAVHPDLHI-------------------PPGFAAFSHATHRASTVVFKNLAD-MRAFg------------ 52 Ralstonia solanacearum 17549002 26 GLaqLLSATSDVVELKRRLqeyvlycqanhvpiqraliDQLESAMSSAIEVAQARIASERGLHADSEld----------- 94 Ralstonia solanacearum 19113041 128 DSidRNRKYTEEIHIPQVYsvlfpskyfgiakqfwqhtGDGISSRRAAAFLHSYKKIQSISEFLVAQrsishlksksrsr 207 fission yeast 1346519 203 ADkaKYLIRKRIATKVVEKid----------------sEGLSDLFSFEHYNESN-GPFNVG--SGEAldd---------- 253 baker's yeast 2500948 193 ADraKELIKKRIATKVIDKdehdeeeny-hflagnqdeQDFQDTFLDSSLNEANHGEDHDGGISGEVdsqee------ph 265 baker's yeast 13476737 1 -----MGINTRLAHSGNNP-------------------HDYFGFVNPPVVHASTVLYRNAA-----Am------------ 39 Mesorhizobium loti 13488085 7 L-----------IHPTAQA-------------------PSGFRSLVTPTYRASTILFERQAD-AADDw------------ 43 Mesorhizobium loti
1CL2_A 48 ---NRANGELFYGRRG--TLTHFSLQQAMCELE-----GGAGCVLFPCGAAAVANS------ILAFIEQ------G---- 101 Escherichia coli 16125673 40 ---YDDDQ-LTYGITG--LSTPVALQNALAELE-----GATNVTLYPSGLAAITGA------MLAVLKA------G---- 92 Caulobacter crescen... 15792713 11 ------DRVLSYGARG--TTTNFELEKLICTLE-----GGYRAQLFPTGLAALAMV------LLNYASK------D---- 61 Campylobacter jejuni 17546358 53 ---HGSVVHWRYGLHA--TPTSDTLCQALAQIE-----GGRHALLLPSGLGAISLV------YFALVKS------G---- 106 Ralstonia solanacearum 17549002 95 -rqTVECEQFARMMLQtkSYVIQCLEWCAPSYEq---sGANQFFDLRAQRNARVNYeryeskEVEVVEQqlaevlGydp- 169 Ralstonia solanacearum 19113041 208 yasHPDLQALNTWMTNegNQANDEMEDVSLYLEerygrNLDLSLATAAKLVLRRRIagtlkdEVDLQKAlp--keGsqyl 285 fission yeast 1346519 254 dqlNSDIPAETITSMGesGSNSTFENTATDDLKfh-vnPNTDVYLFPSGMASIFTA------HRLLLNF------D---- 316 baker's yeast 2500948 266 nglVSTIPPEPIEMSTieEEQSVEEDAGRCALRv---cPERDVFLFPSGMASIFTA------HRLLLQW------D---- 326 baker's yeast 13476737 40 ---AGRSQKYTYGTRG--TPTTDALAQAIDALE-----GSAGTIAVPSGLAAVTIP------LLAFVSA------G---- 93 Mesorhizobium loti 13488085 44 ---RQSEVGYTYGLYG--TPTVLELGARIAELE-----GARHSFVVPGGQAAITLI------YFAFCKA------G---- 97 Mesorhizobium loti
1CL2_A 102 --------DHVLMTNT---A--------------------YEPSQDFCSKILSK---LGVTTSWFDPLIG-ADIVKHLQ- 145 Escherichia coli 16125673 93 --------DEVLVVDS---A--------------------YKPTRRFCDRVLGR---FGVTTRYYDPKLSpEALMGLVT- 137 Caulobacter crescen... 15792713 62 --------AHFLITDAi-----------------------YGPVRTICELFLDK---IGVEIDFLKADAS-DIEEKIKP- 105 Campylobacter jejuni 17546358 107 --------DDVLIPDN---A--------------------YGPTRDHGEWMARQ---FGITVRYYDPMIG-AGIAGLIR- 150 Ralstonia solanacearum 17549002 170 ------eqTAVLLTSSg-mAayaiveafavrellnpndtvLVSPYIYFEASGQLttlKSFDVVFADSYDVgRILAMAKA- 241 Ralstonia solanacearum 19113041 286 revkglshDDVFLFPTgmsAiynthrilrlvlddsrksvcFGFCYVDTLKILQK---WGSGCYFYGLGNDeQLDEFEKRl 362 fission yeast 1346519 317 --------AKRLSRSSsrqDkligygp------pfkktvmFGFPYTDTLSILRKf--NHTHFLGQGDSTSmNALKNILHs 380 baker's yeast 2500948 327 --------SLRLNRSRngsDvtsspp--------nkktviFGFPYADTLHVLQEf--NETYFLGEGDESSmKELTKILHs 388 baker's yeast 13476737 94 --------DHLLIVDS---V--------------------YHPTRNFADTILKR---LGVEVEYYDPHIG-AGIAALIK- 137 Mesorhizobium loti 13488085 98 --------SHALVPAS---A--------------------YGPNRELADGLLAR---LNIEVEAYDPLIG-GGISALIR- 141 Mesorhizobium loti
1CL2_A 146 ---PNTKIVFLESPGS-ITMEVHDVPAIVAAVRSVVp-dAIIMIDNTWAAGVLFKALDFG----IDVSIQAATKYLVGHS 216 Escherichia coli 16125673 138 ---SSTRLIVLEAPGS-LTFEMQDIPAIAAAANAr---gVLTLIDNTWAAGLLFKPLAHG----VTMSVQALTKYVGGHS 206 Caulobacter crescen... 15792713 106 ----NTKLILCESPGS-ILYEIIDLPKLCKIAHAYN---IPVAIDNTYSSGYFLNPLELG----VDISVIAATKYLSGHS 173 Campylobacter jejuni 17546358 151 ---HNTRLVWLEAPGS-VTMEVPDCTAIAEAARAa---gAITAIDNTWSGGLYYQPFAHG----IDISVQALTKYQSGGS 219 Ralstonia solanacearum 17549002 242 ---HQPRVIFLDPLSNtPEQRLIDLDRFFREIGAMVasrVSVVIDGTMSPGCYRREWAAAsdkvEIIYYESCSKYLQLGF 318 Ralstonia solanacearum 19113041 363 esgEKVMALFCEFPSN-PLLNSPDLVRIRKLADSYD---FAVVVDETIGNFVNVEVLPL-----ADVVVSSLTKIFSGDS 433 fission yeast 1346519 381 --gEQILAVFIEAPSN-PLLKMGDLQELKRLSDLYS---FYIVVDETVGGFVNIDVLPY-----ADIVCSSLTKIFSGDS 449 baker's yeast 2500948 389 --gEQILAVFIETPSN-PLLKMGNLLELKRLSELFG---FFIIIDETVGGIVNIDGLPF-----ADIVCSSLTKTFSGDS 457 baker's yeast 13476737 138 ---PNTKVVFTESPAS-NTFEVQDIPAIAKVAHTa---gAIVMMDNTWATPLYFRPLDHG----VDISIHAATKYPAGHS 206 Mesorhizobium loti 13488085 142 ---DNTALIWTESPGS-VTMEIQDVPAIVAAAHAr---gVPVALDNTYAAGVLFDAFAKG----VDVSMQALTKYVGGHS 210 Mesorhizobium loti
1CL2_A 217 DAMIG-TAV-CNARCWEQL--RENAY-LMGQMVDADTA-YITSRGLRTLGVRLRQHHES----SLKVAEWLAE---HPQV 283 Escherichia coli 16125673 207 DCFMG-SVAtCDDAVAKLL--GDAMW-DIGWSVSSDDA-YTMLRGLRTLATRLPRHAEN----GLAIARWLQE---RPEV 274 Caulobacter crescen... 15792713 174 DVTMG-IVViNEKEWKNFD----KLPeALGFTTSPDDA-YLVLRGMRTLDVRMKAHEKS----ADEIVEFLQS---RKEI 240 Campylobacter jejuni 17546358 220 DVLMG-ATItNDEALYHTL--LSTRM-RMGWGVSADDC-FLVLRGLPSLPARLAAHDAH----AREVAEWLAE---RPEV 287 Ralstonia solanacearum 17549002 319 DNVMAgYVLaPVAHREKLG----VIRrNTGAILSRDCAnTFPKYTAETLWKRMDIIARN----AMTVTNYFADlaaVQSI 390 Ralstonia solanacearum 19113041 434 NVMGGsMVLnPSSRYYSRI--KDAMKaLYEDLLYDEDA-LTLERNSRDFAERSQVINHN----AETICNLLYQ---NPKI 503 fission yeast 1346519 450 NVIAGsLVLnPRGKIYEFArkFMKTEdGYEDCLWCEDA-LCLERNSRDFVERTIKVNTNtdilLKRVLLPQVG----KLF 524 baker's yeast 2500948 458 NVIGGsMVLnPQSRVYEFAsrFMQLEdEYEDLLWCEDA-IYLERNSRDFIARTIRINYSteylLDKILKPHVGe--NKLF 534 baker's yeast 13476737 207 DVLLG-TVS-ANESHWEQL--YESFC-TLGCCAGPDDV-YQVLRGLRTMGVRLEHHQRS----ALAIASWLEG---QKGV 273 Mesorhizobium loti 13488085 211 DLLLG-TVSvGTQAAYDAV--GPVLK-QLGAAVSPDDA-SLALRGLQTLGVRLERLESS----TLQVANWLVA---QPGI 278 Mesorhizobium loti
1CL2_A 284 ARVNHPA---LPGSKGHEFWKRDFTG-SSGLFSFVLKKklnnEELANYLDNFSLFSMAYSWGGYESLILAN--QPEHIAA 357 Escherichia coli 16125673 275 ARVLHPA---LPGDAGHAIWKRDFTG-ACGLFGVVLKPcs-qKAVHAFLDSLKLFGLGFSWGGYESLALNC--DPQ--LG 345 Caulobacter crescen... 15792713 241 KTIFYPK---LKSHPNHEIFMRDHKG-ANGMITIEFAEgynkDDAIKFVDKLEYFSIGASWGGYESLATv---T----TP 309 Campylobacter jejuni 17546358 288 VRVLHPA---LPDCPGHAYWKRDFTG-ASGLFSIVLHTryapAQIDAFVEALRYFAIGFSWGGANSLALPYsvPSMRTAT 363 Ralstonia solanacearum 17549002 391 VEVHYPG---HPSHPDHEIGQRYRT--LGGCVSFKFRs---gNDYPKLNRLISELIEVCAARGVRLIKGVSfgHTVPRVS 462 Ralstonia solanacearum 19113041 504 KTLYYPK---YNTSKEHFEACRRENGgYGGLLSVVFHn---pEDARQFYDKIQVAK-GPSLGTNFTLASPYaiLAH-YQE 575 fission yeast 1346519 525 KKIYYPSltsEDTKRNYDSVMSTKDGgYGGLFSLTFFn---iEEAKKFFNNLELCK-GPSLGTNFTLACPYaiIAH-YQE 599 baker's yeast 2500948 535 KKIYYPNltsKETLTNYDMVRCKKEGgYGGLFSLTFHd---eDHAAAFYDNLKLNK-GPSLGTNFTLAFPYtlMTY-YHE 609 baker's yeast 13476737 274 ARVLHPA---LPSHPDHDLWKRDFCG-SSGIFSIVLAGggqkE-QHAFLDALRIFGLGYSWGGYESLAVPV--W----LG 342 Mesorhizobium loti 13488085 279 EAVFHPA---LPSCPGHKFWQRDFTG-SASVFSILFRRevdpGQVEAFVDSLRLFKIGFSWGGTTALAILY--PKLDR-- 350 Mesorhizobium loti
1CL2_A 358 IRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV 395 Escherichia coli 16125673 346 ARSIP-VDLEGPLLRFHIGLEGIEDLKADLRRGFEALN 382 Caulobacter crescentus CB15 15792713 310 PRTATDLSARGLFVRFHIGLEDTKDLIADLTQAFDSIK 347 Campylobacter jejuni 17546358 364 VWPPAGWESAGGLVRLYIGLEDPRDLIADLKKAMeahl 401 Ralstonia solanacearum 17549002 463 ASS-AMAGFDKPYLRLFVGALGTESILALCRAIEATLL 499 Ralstonia solanacearum 19113041 576 LDWAGENGIDRNLVRVSVGMEPSEHLKNVFINALS--- 610 fission yeast 1346519 600 LDEVAQYGVETNLVRVSVGLENSDVLCNVFQRAIEKAL 637 baker's yeast 2500948 610 LDMAEKFGVERNLLRISVGLESQSILGKIFQEAIDKTV 647 baker's yeast 13476737 343 DRVVAKGPYEGPLIRLQIGLEDVDDLKADILGGLAAAT 380 Mesorhizobium loti 13488085 351 ----LGKDYDGRLVRLNIGLEEPCDLIADLEQALGRIN 384 Mesorhizobium loti
Jiyao W et al.(2023). "The conserved domain database in 2023.",