Conserved Protein Domain Family
Inhibitor_I29

?
pfam08246: Inhibitor_I29 (this model, PSSM-Id:219764 is obsolete and has been replaced by 429886)
Cathepsin propeptide inhibitor domain (I29)
This domain is found at the N-terminus of some C1 peptidases such as Cathepsin L where it acts as a propeptide. There are also a number of proteins that are composed solely of multiple copies of this domain such as the peptidase inhibitor salarin. This family is classified as I29 by MEROPS.
Statistics
?
PSSM-Id: 219764
Aligned: 95 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 22-Dec-2011
Updated: 16-Jan-2013
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q7X750        40 YERWRSHHTVS--RSLGDKHKRFNVFKANVMHVHNTN----KMDKPY---KL-KLNKFADMTNHEF 95  soybean
Q24HI2        36 HDDYVLSLARLyrPHLNVEHLEFQHFKESVRRVREHNk---KVNATY---TLsIDSPFAFMSDEQF 95  Tetrahymena thermophila SB210
Q5BTQ1        88 FGKYNEKYSVKh-ADEKERRERYTFFRQDYHDVKSL-----TGKELY---TK-QINRFSDMTDKEL 143 Theileria orientalis
Q4DC63        55 FDRFLQEYGKKy--DAREYVRRRALFEQTLARVRTHNe---AGNHLY---VM-GINHMSDWTPEEL 111 Trypanosoma cruzi
Q05AP8       241 FGPFKEKFNRQy-ESEKEHEERENLFLHTFRFVHSNN----RAGLTY---SV-GINHFADKTKEEL 297 zebrafish
Q86GZ3        38 WDKFRKIYNKTy-GTSEETVYREQVFRRTFNFLRTVDekfkNGTLLY---SV-AVNHFADMTPDEV 98  Rhipicephalus appendiculatus
Q8H3W5        85 HQEWMNKFNREy-KDEAEKAYRFEIFKSTVRFAEKFNae-qVKEHGYckcIL-GTTQFADLTLEEF 147 Oryza sativa Japonica Group
Q6J112       167 FYLFVKEYGRKy-KTEEEMQQRYLAFVENLEKIKAHNs---RENVLY---RK-GMNQFGDLSFGEF 224 malaria parasite P. vivax
XP_001633385 245 FDKYVKKHKKNy-KDNKEHHTRREHFKHNLRFIHSKNr---R-HAGY---YL-AMNHLGDRSDKEL 301 starlet sea anemone
XP_001610695 126 FTRMAKKFDRKy-DTVAERHTAFLNFRRNHDIVKSHEh---NKAATY---TK-DLNHFFDKDikav 183 Babesia bovis T2Bo
Q24HI2        36 HDDYVLSLARLyrPHLNVEHLEFQHFKESVRRVREHNk---KVNATY---TLsIDSPFAFMSDEQF 95  Tetrahymena thermophila SB210
Q5BTQ1        88 FGKYNEKYSVKh-ADEKERRERYTFFRQDYHDVKSL-----TGKELY---TK-QINRFSDMTDKEL 143 Theileria orientalis
Q4DC63        55 FDRFLQEYGKKy--DAREYVRRRALFEQTLARVRTHNe---AGNHLY---VM-GINHMSDWTPEEL 111 Trypanosoma cruzi
Q05AP8       241 FGPFKEKFNRQy-ESEKEHEERENLFLHTFRFVHSNN----RAGLTY---SV-GINHFADKTKEEL 297 zebrafish
Q86GZ3        38 WDKFRKIYNKTy-GTSEETVYREQVFRRTFNFLRTVDekfkNGTLLY---SV-AVNHFADMTPDEV 98  Rhipicephalus appendiculatus
Q8H3W5        85 HQEWMNKFNREy-KDEAEKAYRFEIFKSTVRFAEKFNae-qVKEHGYckcIL-GTTQFADLTLEEF 147 Oryza sativa Japonica Group
Q6J112       167 FYLFVKEYGRKy-KTEEEMQQRYLAFVENLEKIKAHNs---RENVLY---RK-GMNQFGDLSFGEF 224 malaria parasite P. vivax
XP_001633385 245 FDKYVKKHKKNy-KDNKEHHTRREHFKHNLRFIHSKNr---R-HAGY---YL-AMNHLGDRSDKEL 301 starlet sea anemone
XP_001610695 126 FTRMAKKFDRKy-DTVAERHTAFLNFRRNHDIVKSHEh---NKAATY---TK-DLNHFFDKDikav 183 Babesia bovis T2Bo
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap