Conserved Protein Domain Family
tRNA_synt_1c_R2

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pfam04557: tRNA_synt_1c_R2 (this model, PSSM-Id:218148 is obsolete and has been replaced by 428008)
Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
This is a region found N terminal to the catalytic domain of glutaminyl-tRNA synthetase (EC 6.1.1.18) in eukaryotes but not in Escherichia coli. This region is thought to bind RNA in a non-specific manner, enhancing interactions between the tRNA and enzyme, but is not essential for enzyme function.
Statistics
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PSSM-Id: 218148
Aligned: 23 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 22-Dec-2011
Updated: 16-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O62431 161 ITKKEVDLRFLELLGPKTAEDLAPKKKEKKpegPKpskdaaaaatapgTKNQKEASPEEFADGAETMDELLRTrahFHKV 240 Caenorhabditis elegans
Q4RJW3  19 AIKNEVDMQVLHLLGPKTEADLEKKSKKAK---GDenaa------kkeTD---TKSPEMAFEGKSLMDQLRGEalkFHKP 86  spotted green pufferfish
Q2NLA5 162 IIKNEVDMQVLHLLGPKTEADLEKKPKVTK---PKaaep------ekkVD--AIVNGEMKLESVSLMEQLRGEalkFHKP 230 African clawed frog
Q6DRJ2 163 IVKNEVDMQVLHLLGPKTEADLEKKSKAVK---PKapek------dvkIEQASAVNGDGNIENKSLMEQLRGEalkFHKP 233 zebrafish
Q8BML9 164 MIKNEVDMQVLHLLGPKMEADLVKKPKVAK---ARleet------drkTAKDVVEKGEVAGQTLSLMEQLRGEalkFHKP 234 house mouse
Q5F3C0 170 SIKNEVDLQVLHLLGPKTEADLEKKPKAAK---ARpap-------vekQKAAVVENGEVGAETKSLLEQLRGEalkFHKP 239 chicken
Q7Q0M3 161 ALKSEVDVQMFDLLGPKTDADGEKVGKKRR---ETpasdta--pkatsVVEPSAVNANNRPEGPRTMVDLMRNv-dFHRP 234 Anopheles gambiae str...
Q296L9 167 SVKAAIDVEIFDLLGPKTEADLKPPVKQNE---KPkaak------pkpEANPSLQAMEAASDGANTIAELMKTkvhFHAP 237 Drosophila pseudoobscura
Q16Q55 167 AVKNEVDVQMFDLLGPKTEADLAPPPKAEK---KPkgektvaeksvktASKELPSGSESVSDGAKSIAELMKSv-hFHAP 242 yellow fever mosquito
P14325 170 DIKEEVDAAILSLLGPKTDADKAPPAKPVK---PTtpt-------avaTTTAATTTTGDLSPIIPAELKPAKEeikFPDP 239 Dictyostelium discoideum
O62431 241 GENfkqdgyvttPKTAELLKAH 262 Caenorhabditis elegans
Q4RJW3  87 GENfktegyvvtPKTMEMLKKH 108 spotted green pufferfish
Q2NLA5 231 GENyktegyvvtPKTMELLKKH 252 African clawed frog
Q6DRJ2 234 GENyktegyvvtPNTMNLLKKH 255 zebrafish
Q8BML9 235 GENyktpgyvitPYTMDLLKQH 256 house mouse
Q5F3C0 240 GENyktegyvvtPNTMALLKQH 261 chicken
Q7Q0M3 235 GENfktdgyiitPDTERLLKDH 256 Anopheles gambiae str. PEST
Q296L9 238 GENfktdgyvvtEHTERLLKEH 259 Drosophila pseudoobscura
Q16Q55 243 GENhktdgyvvtDQTDRLLTEH 264 yellow fever mosquito
P14325 240 SDNi--------qNTPKLLADH 253 Dictyostelium discoideum
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