1VKZ,2QK4


Conserved Protein Domain Family
GARS_N

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pfam02844: GARS_N (this model, PSSM-Id:217251 is obsolete and has been replaced by 427017)
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Phosphoribosylglycinamide synthetase, N domain
Phosphoribosylglycinamide synthetase catalyzes the second step in the de novo biosynthesis of purine. The reaction catalyzed by Phosphoribosylglycinamide synthetase is the ATP- dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. This domain is related to the N-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase (see pfam00289).
Statistics
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PSSM-Id: 217251
Aligned: 139 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VKZ_B        16 VRVHILGSGGREHAIGWAF---AKQGYEVHFYPG--NAGTKRDGTN--------HPYEGEKTLKAIPEE--DIVIPGSEE 80  Thermotoga mari...
Q9RUF5         1 MKVLVIGSGGREHAIVDACa-rAGH--EVLCTPG--NPGIAAQARLl------aSPQDAPTLADLAVREgaDVVIVGPEA 69  Deinococcus rad...
Q83FJ8         1 MKILVIGSGAREHAIAAAId-sE-GSHEVCVSPG--NAGIAQTINCvq----ttSDADLISIAKn-----fDLVVIGPEG 67  Tropheryma whip...
Q970V3         1 MKVLLIGDGARENALAEALa-nSPKGYKIHAISSytNPGIKEAVDKtngkyfkgNINSVEFVKEIVKEVnpDFGVIGPED 79  Sulfolobus toko...
ZP_02043628    1 MKVLLVGNGGREHAIARALvrtSTPEHPVELVVQagNPALEQLGRSlt-----mDPLDPKDVVRRATSEnvDLVVVGPEA 75  Actinomyces odo...
YP_001056776   2 EKVLVVGDGAREHAIAWAVa-kS--GARIYAAVGhpNPGLVQLAKEtggwhrvvKTTSPGEVVKVAEEVspDLVIIGPEE 78  Pyrobaculum cal...
YP_001154387   2 DRVLVIGDGAREHALAWGLa-rS--GVRLYALMGhlNPGVAQLVREsggsyrlgSPTSAAEAVKAAEEFspDLVVVGPEE 78  Pyrobaculum ars...
YP_001434756   4 ERVLLVGGGGREHAIGERL---VSHGAVLGVAASnlNPGLLSLTKDsggeffkaNPTSPQEVLEVAKKFkaELVVIGPEE 80  Ignicoccus hosp...
YP_001540493   4 SKVLLVGDGAREHAIAEALs-rSVNEPRISALVNhiNPGIRRIVEStggs-lviGPLNQEGVVKAINVInpDLVVIGPEE 81  Caldivirga maqu...
ABQ75843      34 YRVLLVGGGGREHAIATALn--SDERCEVLACASnrNPGIAEIAAAyg----ecGERSPDDIVTFAQTHdaDMAIIGPES 107 uncultured halo...
1VKZ_B        81 FLVEGVSNWRSN----VFGPVKEVARLE 104 Thermotoga maritima
Q9RUF5        70 YLAAGVVDECERrgvpAFGPSQAASRLE 97  Deinococcus radiodurans
Q83FJ8        68 PLAGGLVDRLKSsgatVFGPSQAAARIE 95  Tropheryma whipplei str. Twist
Q970V3        80 PLFHGVANVFREegipVVGPDKECAMIE 107 Sulfolobus tokodaii
ZP_02043628   76 PLVAGVADAVLDygipVFGPTKDAARLE 103 Actinomyces odontolyticus ATCC 17982
YP_001056776  79 PLFAGVADALREagflTFGASAKAAVVE 106 Pyrobaculum calidifontis JCM 11548
YP_001154387  79 PLFAGVSDALRErgfiTLGASSGVAIIE 106 Pyrobaculum arsenaticum DSM 13514
YP_001434756  81 PQFRGVTDALRAagftVFGASSKASEIE 108 Ignicoccus hospitalis KIN4/I
YP_001540493  82 PQFAGVADKAVEmgvpTFGALSRLARIE 109 Caldivirga maquilingensis IC-167
ABQ75843     108 ALEAGVADALTAsgifTFGPQAASARIE 135 uncultured haloarchaeon
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