2XD7,1YD9,1VHU,1SPV,2X47


Conserved Protein Domain Family
Macro

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pfam01661: Macro (this model, PSSM-Id:216634 is obsolete and has been replaced by 307680)
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Macro domain
This domain is an ADP-ribose binding module. It is found in a number of otherwise unrelated proteins. It is found at the C-terminus of the macro-H2A histone protein. This domain is found in the non-structural proteins of several types of ssRNA viruses such as NSP3 from alphaviruses. This domain is also found on its own in a family of proteins from bacteria, archaebacteria, and eukaryotes.
Statistics
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PSSM-Id: 216634
View PSSM: pfam01661
Aligned: 124 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XD7_C       40 VHPTTAEIDL-----KED-IGKALEKAGGKEFLETV-KELrksqGp-LEVAEAAVSQSSGLAa-kFVIHChiPQWgs--- 107
gi 81522220  44 VSAANSFGLM-----DGG-VDAAITAYFGPQLQERVqQHIlreyLgeQPVGTAFVIETGNSKy-pWLVHA--PTMrvpli 114
gi 81709016  18 INTVNCVGVM-----GRG-VALQFRKAYPENFKAYE-SACkr---keVRLGEVFVHDLHSFInprYIINF--PTKdhwk- 84
gi 81402714  18 VNTVNCVGVM-----GRG-IALQFKKAFPENFKAYA-QACke---ekVKPGEMFVFQTGQLVnprFIINF--PTKrhwr- 84
gi 75436417  22 VNTVNTVGVM-----GKG-IALMFKERFKENFLRYA-AACkd---nqVRIGKIFVTEVNELDgprWIINF--PTKqhwr- 88
gi 81669473  18 VNTVNCVGVM-----GKG-IALQFKRRYPEMFTAYE-KACkr---geVTIGKMFVVDTGQLDgpkHIINF--PTKkhwr- 84
gi 81346447  18 VNTVNCVGVM-----GKG-IALQFKQAYPEMFSEYE-KACrr---keVQPGKMHVVSTKSLLnpkYIINF--PTKrhwk- 84
gi 75540551  18 VNTVNCVGVM-----GRG-IALQFKNMYPANFKAYE-AACkr---eeVQPGRMFVFETKQLTpprLIINF--PTKrhwr- 84
gi 74786390  98 VNSVGPDFEL-----SKGqVSAILLRRVGPQLQTEC-TNNp-----kFATESYRITTGGNLCd--HIVHYvl-------- 156
gi 74864063 114 VNGTNKVFELmkegnGYD-CSGNFLKTCGDELLNDM-KNAkeqnKg----KSIILTKGYNSSy-kHIIHVvePYYn---- 182
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
2XD7_C      108 ---dkCEEQLEETIKNCLSA-----AEDKKLKSVAFPPFPSGRNCFPKQTAAQVT 154
gi 81522220 115 idgtdAVYNATRAALLAIFQhnksaGEDRKIKSVVFPAMGAGCGQVSPGSVARQM 169
gi 81709016  85 --gssRLSYIESGLRSLIGE-----VEKLGIRSLALPPLGCGLGGLDWREVRPLI 132
gi 81402714  85 --thsRIDDIENGLKALKCT-----IQKYKIRSIAIPPLGCGLGGLDWAEVKTRI 132
gi 75436417  89 --gdsRIEWITEGLQDLHRF-----LIENKVKSIAIPPLGAGNGGLDWAEVRPLI 136
gi 81669473  85 --apsKLAYIDAGLIDLIRV-----IRELNIASVAVPPLGVGNGGLDWEDVEQRL 132
gi 81346447  85 --nksRMEDIELGLADLIKV-----VKELNIKSIALPPLGCGNGGLRWDEVRPKI 132
gi 75540551  85 --gksRIEDIEAGLVDLVNV-----IRDKNIRSIAIPPLGAGLGGLDWKEVRPRI 132
gi 74786390 157 ---pnKEYRIEESIMELLEK-----CDNMEAITVVMPVLGSGNRGVPVDKCARFL 203
gi 74864063 183 -----QTQKLKNCYENILLT-----AKDNNFKNIVFPLLGSGISLFKKHDVVISC 227
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