3QFS,1F20,2BPO,1DDG


Conserved Protein Domain Family
FAD_binding_1

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pfam00667: FAD_binding_1 (this model, PSSM-Id:216051 is obsolete and has been replaced by 395540)
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FAD binding domain
This domain is found in sulfite reductase, NADPH cytochrome P450 reductase, Nitric oxide synthase and methionine synthase reductase.
Statistics
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PSSM-Id: 216051
Aligned: 19 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3QFS_A   56 PFDAKNPFLAAVTTNRKLNQ-GTERHLMHLELDISD-S----KIRYESGDHVAVYPANDSALVNQLGKILGADL---DVV 126  human
P50126  260 PFDHTHPYLAKISKTRELFA-SKERNCVHVEFDVSE-S----NLKYTTGDHLAVWPSNSDENIAKFIKCFGLDDk-iNTV 332  Candida maltosa
P35228  726 SMHAKNVFTMRLKSRQNLQSpTSSRATILVELSCED-Gq---GLNYLPGEHLGVCPGNQPALVQGILERVVDGPt-pHQT 800  human
P29473  754 HVHRRKMFQATVLSVENLQSsKSTRATILVRLDTAG-Qe---GLQYQPGDHIGICPPNRPGLVEALLSRVEDPPp-pTES 828  cattle
Q09744  134 PFS---VFPAPILDVRELTKpGAVKRVFHFELDVSN-YplpeGEEWMVGGSFGVMAPNNEEDVDELLQLLHINPdqaDAP 209  Schizosaccharomyces...
P38038  230 PYSKDAPLVASLSVNQKITGrNSEKDVRHIEIDLGD-S----GMRYQPGDALGVWYQNDPALVKELVELLWLKG---DEP 301  Escherichia coli K-12
P39692  644 PDLPVKNFVVKVKENRRVTPaDYDRYIFHIEFDISG-T----GMTYDIGEALGIHARNNESLVKEFLTFYGLNE---SDV 715  Saccharomyces cerev...
Q09878  618 PDVSEKVFTVHVRANKRLTPaEYNRNIFHIEFDLGD-S----GLTYDIGEALGVYGVNNKTHVHDFIEEYGLDA---NEL 689  Schizosaccharomyces...
P29475  991 NVHKKRVSAARLLSRQNLQSpKSSRSTIFVRLHTNG-Sq---ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPp-vNQM 1065 human
1F20_A   24 NVHKKRVSAARLLSRQNLQSpKSSRSTIFVRLHTNGnQ----ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPp-aNHV 98   Norway rat
P50126  260 PFDHTHPYLAKISKTRELFA-SKERNCVHVEFDVSE-S----NLKYTTGDHLAVWPSNSDENIAKFIKCFGLDDk-iNTV 332  Candida maltosa
P35228  726 SMHAKNVFTMRLKSRQNLQSpTSSRATILVELSCED-Gq---GLNYLPGEHLGVCPGNQPALVQGILERVVDGPt-pHQT 800  human
P29473  754 HVHRRKMFQATVLSVENLQSsKSTRATILVRLDTAG-Qe---GLQYQPGDHIGICPPNRPGLVEALLSRVEDPPp-pTES 828  cattle
Q09744  134 PFS---VFPAPILDVRELTKpGAVKRVFHFELDVSN-YplpeGEEWMVGGSFGVMAPNNEEDVDELLQLLHINPdqaDAP 209  Schizosaccharomyces...
P38038  230 PYSKDAPLVASLSVNQKITGrNSEKDVRHIEIDLGD-S----GMRYQPGDALGVWYQNDPALVKELVELLWLKG---DEP 301  Escherichia coli K-12
P39692  644 PDLPVKNFVVKVKENRRVTPaDYDRYIFHIEFDISG-T----GMTYDIGEALGIHARNNESLVKEFLTFYGLNE---SDV 715  Saccharomyces cerev...
Q09878  618 PDVSEKVFTVHVRANKRLTPaEYNRNIFHIEFDLGD-S----GLTYDIGEALGVYGVNNKTHVHDFIEEYGLDA---NEL 689  Schizosaccharomyces...
P29475  991 NVHKKRVSAARLLSRQNLQSpKSSRSTIFVRLHTNG-Sq---ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPp-vNQM 1065 human
1F20_A   24 NVHKKRVSAARLLSRQNLQSpKSSRSTIFVRLHTNGnQ----ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPp-aNHV 98   Norway rat
3QFS_A  127 MSLNNLDEe---------SnKKHPFPCPTSYRTALTYYLDITN-PPRTNVLYELAQYASEPSEQELLRKMASSsgegKEL 196  human
P50126  333 FELKALDSt-----------YQIPFPNPITYGAVVRHHLEISG-PVSRQFFLAIAGFAPDEETKKTFTRIGNDkqefANK 400  Candida maltosa
P35228  801 VRLEALDesg------syW-VSDKRLPPCSLSQALTYFLDITT-PPTQLLLQKLAQVATEEPERQRLEALCQ-----PSE 867  human
P29473  829 VAVEQLEkgspg-gpppsW-VRDPRLPPCTLRQALTFFLDITS-PPSPRLLRLLSTLAEEPSEQQELETLSQD----PRR 901  cattle
Q09744  210 VLLKTDGGrwp----tiwA-EDTPRELVTTRRELLKWTVEFMSvAPKKQLIRLLAEYAKDDTERQVLLFLVSRl--gQRA 282  Schizosaccharomyces...
P38038  302 VTVEGKT---------------------LPLNEALQWHFELTV--NTANIVENYATLTRSET----LLPLVGD----KAK 350  Escherichia coli K-12
P39692  716 VLVPNKD--------------NHHLLETRTVLQAFVENLDIFG-KPPKRFYESLIPYASNEEEKKKLEDLVTPa--gAVD 778  Saccharomyces cerev...
Q09878  690 IHVPSIQ--------------HPGHWETRTVFQALCQNIDIFG-KPTKKFHEQLLEFETDEKERADLQILISPa--gAPD 752  Schizosaccharomyces...
P29475 1066 VKVELLEErntalgvisnW-TDELRLPPCTIFQAFKYYLDITT-PPTPLQLQQFASLATSEKEKQRLLVLSKG----LQE 1139 human
1F20_A   99 VKVEMLEErntalgvisnW-KDESRLPPCTIFQAFKYYLDITT-PPTPLQLQQFASLATNEKEKQRLLVLSk----gLQE 172  Norway rat
P50126  333 FELKALDSt-----------YQIPFPNPITYGAVVRHHLEISG-PVSRQFFLAIAGFAPDEETKKTFTRIGNDkqefANK 400  Candida maltosa
P35228  801 VRLEALDesg------syW-VSDKRLPPCSLSQALTYFLDITT-PPTQLLLQKLAQVATEEPERQRLEALCQ-----PSE 867  human
P29473  829 VAVEQLEkgspg-gpppsW-VRDPRLPPCTLRQALTFFLDITS-PPSPRLLRLLSTLAEEPSEQQELETLSQD----PRR 901  cattle
Q09744  210 VLLKTDGGrwp----tiwA-EDTPRELVTTRRELLKWTVEFMSvAPKKQLIRLLAEYAKDDTERQVLLFLVSRl--gQRA 282  Schizosaccharomyces...
P38038  302 VTVEGKT---------------------LPLNEALQWHFELTV--NTANIVENYATLTRSET----LLPLVGD----KAK 350  Escherichia coli K-12
P39692  716 VLVPNKD--------------NHHLLETRTVLQAFVENLDIFG-KPPKRFYESLIPYASNEEEKKKLEDLVTPa--gAVD 778  Saccharomyces cerev...
Q09878  690 IHVPSIQ--------------HPGHWETRTVFQALCQNIDIFG-KPTKKFHEQLLEFETDEKERADLQILISPa--gAPD 752  Schizosaccharomyces...
P29475 1066 VKVELLEErntalgvisnW-TDELRLPPCTIFQAFKYYLDITT-PPTPLQLQQFASLATSEKEKQRLLVLSKG----LQE 1139 human
1F20_A   99 VKVEMLEErntalgvisnW-KDESRLPPCTIFQAFKYYLDITT-PPTPLQLQQFASLATNEKEKQRLLVLSk----gLQE 172  Norway rat
3QFS_A  197 YLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYEt--KAGRINKGVATNW 274  human
P50126  401 ITRKKLNVADALLFASNGRPWSDVPFEFIIENVPHLQPRYYSISSSSLSEKQTINITAVVEVEee--aDGRAVTGVVTNL 478  Candida maltosa
P35228  868 YSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHtrdGQGPLHHGVCSTW 947  human
P29473  902 YEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPNAHPGEVHLTVAVLAYRtqdGLGPLHYGVCSTW 981  cattle
Q09744  283 FCDLR-DHNVTLITLLKAFPSVQLPLDHLLTVLPQLMPRWYSLSNDPKVSNNVLEFAVTVVEINk--VEGGTRSGIGSGF 359  Schizosaccharomyces...
P38038  351 LQHYA---ATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYd---VEGRARAGGASSF 424  Escherichia coli K-12
P39692  779 LKRFQDVEYYTYADIFELFPSVRPSLEELVTIIEPLKRREYSIASSQKVHPNEVHLLIVVVDWVd--NKGRKRYGQASKY 856  Saccharomyces cerev...
Q09878  753 FKRRAEVDMLTYADVLKEFKHAKLTAAQIAQIVPVIKRREYSISSSQKKHNDSVHLLVVVVGWKd--GMGRDRYGQCSHY 830  Schizosaccharomyces...
P29475 1140 YEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRtrdGEGPIHHGVCSSW 1219 human
1F20_A  173 YEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHtrdGEGPVHHGVCSSW 252  Norway rat
P50126  401 ITRKKLNVADALLFASNGRPWSDVPFEFIIENVPHLQPRYYSISSSSLSEKQTINITAVVEVEee--aDGRAVTGVVTNL 478  Candida maltosa
P35228  868 YSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHtrdGQGPLHHGVCSTW 947  human
P29473  902 YEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPNAHPGEVHLTVAVLAYRtqdGLGPLHYGVCSTW 981  cattle
Q09744  283 FCDLR-DHNVTLITLLKAFPSVQLPLDHLLTVLPQLMPRWYSLSNDPKVSNNVLEFAVTVVEINk--VEGGTRSGIGSGF 359  Schizosaccharomyces...
P38038  351 LQHYA---ATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYd---VEGRARAGGASSF 424  Escherichia coli K-12
P39692  779 LKRFQDVEYYTYADIFELFPSVRPSLEELVTIIEPLKRREYSIASSQKVHPNEVHLLIVVVDWVd--NKGRKRYGQASKY 856  Saccharomyces cerev...
Q09878  753 FKRRAEVDMLTYADVLKEFKHAKLTAAQIAQIVPVIKRREYSISSSQKKHNDSVHLLVVVVGWKd--GMGRDRYGQCSHY 830  Schizosaccharomyces...
P29475 1140 YEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRtrdGEGPIHHGVCSSW 1219 human
1F20_A  173 YEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHtrdGEGPVHHGVCSSW 252  Norway rat
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