Q4P4A0 1433 LSYGSGSVARQMCLIEAEL----L----R----SVSWDELASSRWRErr-fG----------Aevtdweafyrdrvrdrl 1489 Ustilago maydis Q6BZP3 408 LDTSIDLLASQVYYFHLQF----S----G----AWSPASDMSLLFGG----R----------Wny--------------- 446 Yarrowia lipo... Q6CQ00 503 LKLDNAILADQIHAINLTYnkiwS----P----QKDYSLLYDSAF-Nkn-yI----------D----------------- 545 Kluyveromyces... Q9HF75 468 LKLDTEKVANQIHKINLTFnrvwS----P----QADYSLLYDSQYTQkh-vE---------------------------- 510 Ashbya gossyp... P39960 589 LSLDITTLADEVHHINLKFdkvwA----P----KFDYSLLYDSKFINrr-iV----------S----------------- 632 Saccharomyces... Q6FQG1 602 MELDPSKFAEEVHSINLEFnkvwA----P----RKDFSLLYDSKFNNkn-iL----------S----------------- 645 Candida glabrata Q5AGW7 552 KEINLIDFAYTISEIDLKFfsnwN----S----NIDKSLLLYSSISDdt-nR----------Dff--------------- 597 Candida albicans EDK36060 377 kDIDLIEFAAVVTSIDLKF----FkawnS----NIDKSLLLFSSLNN----Shs-------sDyf--------------- 422 Pichia guilli... XP_001523706 640 kDVNLIEFAKTISDLDLKY----F----SswnsNIDKSLLLASSINTtketK----------Nqf--------------- 686 Lodderomyces ... XP_001383582 292 kDINLVDFVQAISAIDLKF----FkhwnS----NIDKSLLLYSSING----NfdsssshgtaDyf--------------- 344 Pichia stipit... Q6BZP3 408 LDTSIDLLASQVYYFHLQF----S----G----AWSPASDMSLLFGG----R----------Wny--------------- 446 Yarrowia lipo... Q6CQ00 503 LKLDNAILADQIHAINLTYnkiwS----P----QKDYSLLYDSAF-Nkn-yI----------D----------------- 545 Kluyveromyces... Q9HF75 468 LKLDTEKVANQIHKINLTFnrvwS----P----QADYSLLYDSQYTQkh-vE---------------------------- 510 Ashbya gossyp... P39960 589 LSLDITTLADEVHHINLKFdkvwA----P----KFDYSLLYDSKFINrr-iV----------S----------------- 632 Saccharomyces... Q6FQG1 602 MELDPSKFAEEVHSINLEFnkvwA----P----RKDFSLLYDSKFNNkn-iL----------S----------------- 645 Candida glabrata Q5AGW7 552 KEINLIDFAYTISEIDLKFfsnwN----S----NIDKSLLLYSSISDdt-nR----------Dff--------------- 597 Candida albicans EDK36060 377 kDIDLIEFAAVVTSIDLKF----FkawnS----NIDKSLLLFSSLNN----Shs-------sDyf--------------- 422 Pichia guilli... XP_001523706 640 kDVNLIEFAKTISDLDLKY----F----SswnsNIDKSLLLASSINTtketK----------Nqf--------------- 686 Lodderomyces ... XP_001383582 292 kDINLVDFVQAISAIDLKF----FkhwnS----NIDKSLLLYSSING----NfdsssshgtaDyf--------------- 344 Pichia stipit...
Q4P4A0 1490 eaqrlgelhQEHAVEAIVARFNLTSNWVASEVVLT-Q-------NI----------DERAAVISKLIRIAWK-CYLQSNF 1550 Ustilago maydis Q6BZP3 447 -------wrHNPLIFDSLS-VHFLGGVLLEHLFSG-Sga----vSS----------AYRGKLLSHWISLGNA-LKNCGDM 502 Yarrowia lipo... Q6CQ00 546 ---------LNPLVFNNRSNIHYVSRLLIEHLFKQiDgt---plHP----------KERALVLTKWVQLG-CtFEKIGDM 602 Kluyveromyces... Q9HF75 511 ---------LNPLVFFNDKNVQYLSRLMVSHIFCEeTg-----fTP----------KKRAEVLTKWVQLG-CkFERLGDM 565 Ashbya gossyp... P39960 633 ---------LNPLVFNNDQNIHFLGRLLISHLFPTnPefs-kkvTP----------KVRAELLDKWVQIG-CrFEHLGDM 691 Saccharomyces... Q6FQG1 646 ---------LSPLIFNNKDNVHFLGRLLVTHLFSTnHrs---keQC----------RKTAEVLNRWVLLG-CkFEQLGDM 702 Candida glabrata Q5AGW7 598 -------ykKNPLIFNNDYHIHYLSRLLVNHLFVEnSsmnmssaNL----------ENKARLLEKWIDLG-ClLDKSGNM 659 Candida albicans EDK36060 423 -------ykKNTLMFNNDTHIHYLSRLFINHLFIE-G-------TSpgistsalsfEKKARLIEKWIDLGCL-LDKLGNM 486 Pichia guilli... XP_001523706 687 -------ykKNPLIFNNNKHIHYLSRLLINHIFVE-Q-------ALarsms-failESKARILEKWIDLGCL-LDKSGNM 749 Lodderomyces ... XP_001383582 345 -------ykKNPLIFNNDHHIHYLSRLLINHIFVE-S-------SSstls--ssslERKARLLEKWIDLGCL-LDKSGNM 406 Pichia stipit... Q6BZP3 447 -------wrHNPLIFDSLS-VHFLGGVLLEHLFSG-Sga----vSS----------AYRGKLLSHWISLGNA-LKNCGDM 502 Yarrowia lipo... Q6CQ00 546 ---------LNPLVFNNRSNIHYVSRLLIEHLFKQiDgt---plHP----------KERALVLTKWVQLG-CtFEKIGDM 602 Kluyveromyces... Q9HF75 511 ---------LNPLVFFNDKNVQYLSRLMVSHIFCEeTg-----fTP----------KKRAEVLTKWVQLG-CkFERLGDM 565 Ashbya gossyp... P39960 633 ---------LNPLVFNNDQNIHFLGRLLISHLFPTnPefs-kkvTP----------KVRAELLDKWVQIG-CrFEHLGDM 691 Saccharomyces... Q6FQG1 646 ---------LSPLIFNNKDNVHFLGRLLVTHLFSTnHrs---keQC----------RKTAEVLNRWVLLG-CkFEQLGDM 702 Candida glabrata Q5AGW7 598 -------ykKNPLIFNNDYHIHYLSRLLVNHLFVEnSsmnmssaNL----------ENKARLLEKWIDLG-ClLDKSGNM 659 Candida albicans EDK36060 423 -------ykKNTLMFNNDTHIHYLSRLFINHLFIE-G-------TSpgistsalsfEKKARLIEKWIDLGCL-LDKLGNM 486 Pichia guilli... XP_001523706 687 -------ykKNPLIFNNNKHIHYLSRLLINHIFVE-Q-------ALarsms-failESKARILEKWIDLGCL-LDKSGNM 749 Lodderomyces ... XP_001383582 345 -------ykKNPLIFNNDHHIHYLSRLLINHIFVE-S-------SSstls--ssslERKARLLEKWIDLGCL-LDKSGNM 406 Pichia stipit...
Q4P4A0 1551 ASLAQIIFGLNTPWVQRLRRTWSRVGYFETRM-W-----------------------------------R--------DL 1586 Ustilago maydis Q6BZP3 503 VGWLGIAGVVCSPPVLRLRDSWGFVSTEIKDSvT-----------------------------------K--------EW 539 Yarrowia lipo... Q6CQ00 603 VSWLAIATIICSTPILRLSLTWQYISDQTLKIiF-----------------------------------K--------DW 639 Kluyveromyces... Q9HF75 566 VSWLAIATVICSIPVLRLTRTWQYVPDSYLKIiF-----------------------------------K--------DW 602 Ashbya gossyp... P39960 692 VSWLAVATIICSIPVLR-SSSWKYVPDQSLKTiF-----------------------------------K--------DW 727 Saccharomyces... Q6FQG1 703 VSWLAIATVICSIPILRLGAIWKYMPESTVKIiL-----------------------------------N--------DW 739 Candida glabrata Q5AGW7 660 SSWLGISSVILSQPVLRLTKIWSLVAPDYIRLlK-----------------------------------S--------DW 696 Candida albicans EDK36060 487 SSWLGISSIILSQPILRLTKIWSLVSPDYIKL-L-----------------------------------Kn-------DW 523 Pichia guilli... XP_001523706 750 SSWLGISSIILSQPVLRLTKIWSLVSNDYIKL-L-----------------------------------KndwspvlfEL 793 Lodderomyces ... XP_001383582 407 SSWLGISSIILSQPVLRLTKIWSLVSPNYIKL-LksdwspvlfeldrrhlangtsyeklhsspsaspdkD--------DL 477 Pichia stipit... Q6BZP3 503 VGWLGIAGVVCSPPVLRLRDSWGFVSTEIKDSvT-----------------------------------K--------EW 539 Yarrowia lipo... Q6CQ00 603 VSWLAIATIICSTPILRLSLTWQYISDQTLKIiF-----------------------------------K--------DW 639 Kluyveromyces... Q9HF75 566 VSWLAIATVICSIPVLRLTRTWQYVPDSYLKIiF-----------------------------------K--------DW 602 Ashbya gossyp... P39960 692 VSWLAVATIICSIPVLR-SSSWKYVPDQSLKTiF-----------------------------------K--------DW 727 Saccharomyces... Q6FQG1 703 VSWLAIATVICSIPILRLGAIWKYMPESTVKIiL-----------------------------------N--------DW 739 Candida glabrata Q5AGW7 660 SSWLGISSVILSQPVLRLTKIWSLVAPDYIRLlK-----------------------------------S--------DW 696 Candida albicans EDK36060 487 SSWLGISSIILSQPILRLTKIWSLVSPDYIKL-L-----------------------------------Kn-------DW 523 Pichia guilli... XP_001523706 750 SSWLGISSIILSQPVLRLTKIWSLVSNDYIKL-L-----------------------------------KndwspvlfEL 793 Lodderomyces ... XP_001383582 407 SSWLGISSIILSQPVLRLTKIWSLVSPNYIKL-LksdwspvlfeldrrhlangtsyeklhsspsaspdkD--------DL 477 Pichia stipit...
Q4P4A0 1587 ----------------------NSF------------V----------------------------GPRHNFRHL--R-- 1600 Ustilago maydis Q6BZP3 540 ----------------------APVvfdlerrlrvtdM----------------------------SRKSTYHVL--Apq 567 Yarrowia lipo... Q6CQ00 640 ----------------------VPTivqler-rqlsfR----------------------------TTNSVFILAppNln 668 Kluyveromyces... Q9HF75 603 ----------------------VPTivqldr-rqmssK----------------------------SMNSVFILAppNln 631 Ashbya gossyp... P39960 728 ----------------------VPTiiqler-rqrtsK----------------------------STSSVFILAppNld 756 Saccharomyces... Q6FQG1 740 ----------------------VPTivqldr-rqissK----------------------------STGSVFILAppNld 768 Candida glabrata Q5AGW7 697 ----------------------SPVlfeldr-rylvnEstidhgksth--------lggneesrdlSTKDSYHIMapRgl 745 Candida albicans EDK36060 524 ----------------------SPV------------LfeldrrhlanglvkantsgqtsngkeesNPRESYHIM--A-- 565 Pichia guilli... XP_001523706 794 drrylvhetsggdnglstlgekQEL------------T----------------------------PSKESYHIMapR-- 831 Lodderomyces ... XP_001383582 478 ----------------------RDS------------I----------------------------NFKDSYHIM--A-- 491 Pichia stipit... Q6BZP3 540 ----------------------APVvfdlerrlrvtdM----------------------------SRKSTYHVL--Apq 567 Yarrowia lipo... Q6CQ00 640 ----------------------VPTivqler-rqlsfR----------------------------TTNSVFILAppNln 668 Kluyveromyces... Q9HF75 603 ----------------------VPTivqldr-rqmssK----------------------------SMNSVFILAppNln 631 Ashbya gossyp... P39960 728 ----------------------VPTiiqler-rqrtsK----------------------------STSSVFILAppNld 756 Saccharomyces... Q6FQG1 740 ----------------------VPTivqldr-rqissK----------------------------STGSVFILAppNld 768 Candida glabrata Q5AGW7 697 ----------------------SPVlfeldr-rylvnEstidhgksth--------lggneesrdlSTKDSYHIMapRgl 745 Candida albicans EDK36060 524 ----------------------SPV------------LfeldrrhlanglvkantsgqtsngkeesNPRESYHIM--A-- 565 Pichia guilli... XP_001523706 794 drrylvhetsggdnglstlgekQEL------------T----------------------------PSKESYHIMapR-- 831 Lodderomyces ... XP_001383582 478 ----------------------RDS------------I----------------------------NFKDSYHIM--A-- 491 Pichia stipit...
Q4P4A0 1601 ---NA-MLkvaegnagesgpgdfsaspravdagKAGStrACIPFFGlfvSDLMQYDAM---PTfldptvptmaattafdq 1673 Ustilago maydis Q6BZP3 568 gigQS-YP---------------------------KE--RVVPFFG----DLCVRYED---GS----------------- 593 Yarrowia lipo... Q6CQ00 669 --eKS-IRe------------------------------NVIPYFG----DLTIHTNDltqDTm---------------- 695 Kluyveromyces... Q9HF75 632 --dAF-VRd------------------------------NVIPYFG----DLVIHSDDlprDSk---------------- 658 Ashbya gossyp... P39960 757 --dDF-TRa------------------------------NVISYFG----DLLIHADDlpsDTk---------------- 783 Saccharomyces... Q6FQG1 769 --dPN-IKn------------------------------NIVSYFG----DLIIHADDlpnDVk---------------- 795 Candida glabrata Q5AGW7 746 --gKI-YPk-----------------------------eRVIPFFG----DLVINNSGnttDKsv--------------- 774 Candida albicans EDK36060 566 ---PRgIG-------------------------KIYPkeRVIPYFG----DLV-IQNA---VP----------------- 592 Pichia guilli... XP_001523706 832 ---GL-GK-------------------------IYAKe-RVIPYF----SDLVINNLG---LT----------------- 857 Lodderomyces ... XP_001383582 492 ---PRgLG-------------------------KIYPkeRVIPYFG----DLVINNNS---TA----------------- 519 Pichia stipit... Q6BZP3 568 gigQS-YP---------------------------KE--RVVPFFG----DLCVRYED---GS----------------- 593 Yarrowia lipo... Q6CQ00 669 --eKS-IRe------------------------------NVIPYFG----DLTIHTNDltqDTm---------------- 695 Kluyveromyces... Q9HF75 632 --dAF-VRd------------------------------NVIPYFG----DLVIHSDDlprDSk---------------- 658 Ashbya gossyp... P39960 757 --dDF-TRa------------------------------NVISYFG----DLLIHADDlpsDTk---------------- 783 Saccharomyces... Q6FQG1 769 --dPN-IKn------------------------------NIVSYFG----DLIIHADDlpnDVk---------------- 795 Candida glabrata Q5AGW7 746 --gKI-YPk-----------------------------eRVIPFFG----DLVINNSGnttDKsv--------------- 774 Candida albicans EDK36060 566 ---PRgIG-------------------------KIYPkeRVIPYFG----DLV-IQNA---VP----------------- 592 Pichia guilli... XP_001523706 832 ---GL-GK-------------------------IYAKe-RVIPYF----SDLVINNLG---LT----------------- 857 Lodderomyces ... XP_001383582 492 ---PRgLG-------------------------KIYPkeRVIPYFG----DLVINNNS---TA----------------- 519 Pichia stipit...
Q4P4A0 1674 dgHVRVHPadphvfddlaplppgvhlepLINVLKF--RS 1710 Ustilago maydis Q6BZP3 594 --SFRQC---------------------ESRLNRI--RT 607 Yarrowia lipolytica Q6CQ00 696 -fRYLEK---------------------KIYRTKNafQK 712 Kluyveromyces lactis Q9HF75 659 -yKYLEK---------------------KIRRTKNafYK 675 Ashbya gossypii ATCC 10895 P39960 784 -fKYLEK---------------------KINRTKNafHK 800 Saccharomyces cerevisiae S288c Q6FQG1 796 -iKYLAK---------------------KINRTKNafHK 812 Candida glabrata Q5AGW7 775 diYELES---------------------IWKRVNYsfDR 792 Candida albicans EDK36060 593 --NVTELE--------------------SIwkrinysfn 609 Pichia guilliermondii ATCC 6260 XP_001523706 858 --ENVDvyelesiwkrinysfdrwndylsnlnnhdeiik 894 Lodderomyces elongisporus NRRL YB-4239 XP_001383582 520 --DIFELE--------------------SIwkrinysfs 536 Pichia stipitis CBS 6054 Q6BZP3 594 --SFRQC---------------------ESRLNRI--RT 607 Yarrowia lipolytica Q6CQ00 696 -fRYLEK---------------------KIYRTKNafQK 712 Kluyveromyces lactis Q9HF75 659 -yKYLEK---------------------KIRRTKNafYK 675 Ashbya gossypii ATCC 10895 P39960 784 -fKYLEK---------------------KINRTKNafHK 800 Saccharomyces cerevisiae S288c Q6FQG1 796 -iKYLAK---------------------KINRTKNafHK 812 Candida glabrata Q5AGW7 775 diYELES---------------------IWKRVNYsfDR 792 Candida albicans EDK36060 593 --NVTELE--------------------SIwkrinysfn 609 Pichia guilliermondii ATCC 6260 XP_001523706 858 --ENVDvyelesiwkrinysfdrwndylsnlnnhdeiik 894 Lodderomyces elongisporus NRRL YB-4239 XP_001383582 520 --DIFELE--------------------SIwkrinysfs 536 Pichia stipitis CBS 6054
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",