1SEM,1VA7,1ZUU,2VKN,2JW4,1W1F,3REB,1Z9Z,1OOT


Conserved Protein Domain Family
SH3_1

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pfam00018: SH3_1 (this model, PSSM-Id:215659 is obsolete and has been replaced by 394975)
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SH3 domain
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase. The structure is a partly opened beta barrel.
Statistics
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PSSM-Id: 215659
Aligned: 61 rows
Threshold Bit Score: -1
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1SEM_A    6 QALFDFNPQE-SGELAFKRGDVITLINKDDPNWWEGQLNn-----RRGIFPS 51   Caenorhabditis elegans
P34258  197 IAKFDYAPTQ-SDEMGLRIGDTVLISKKVDAEWFYGENQnq---rTFGIVPS 244  Caenorhabditis elegans
P19878  463 EALFSYEATQ-PEDLEFQEGDIILVLSKVNEEWLEGECKg-----KVGIFPK 508  human
P34258  277 TAIYDYNSNE-AGDLNFAVGSQIMVTARVNEEWLEGECFg-----RSGIFPS 322  Caenorhabditis elegans
1VA7_A    7 EAAYDFPGSGsSSELPLKKGDIVFISRDEPSGWSLAKLLdg---sKEGWVPT 55   baker's yeast
P14598  162 RAIANYEKTS-GSEMALSTGDVVEVVEKSESGWWFCQMKa-----KRGWIPA 207  human
P43069   36 IALYDFPGTQ-SSHLPLNLGDTIHVLSKSATGWWDGVVMgnsgelQRGWFPH 86   Candida albicans SC5314
P27637  265 YALYAFNGHD-SSHCQLGQDEPCILLNDQDAYWWLVKRItd---gKIGFAPA 312  Saccharomyces cerevisiae S288c
P29366  161 IVLYDFKAEK-ADELTTYVGENLFICAHHNCEWFIAKPIgr--lgGPGLVPV 209  Saccharomyces cerevisiae S288c
P40996  129 IVQFDFAAER-PDELEAKAGEAIIIIARSNHEWLVAKPIgr--lgGPGLIPL 177  Schizosaccharomyces pombe 972h-
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