1SEM,1VA7,1ZUU,2VKN,2JW4,1W1F,3REB,1Z9Z,1OOT


Conserved Protein Domain Family
SH3_1

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pfam00018: SH3_1 (this model, PSSM-Id:215659 is obsolete and has been replaced by 333770)
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SH3 domain
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase. The structure is a partly opened beta barrel.
Statistics
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PSSM-Id: 215659
View PSSM: pfam00018
Aligned: 61 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
1SEM_A          6 QALFDFNPQE-SGELAFKRGDVITLINKDDPNWWEGQLNn-----RRGIFPS 51
gi 50403736   197 IAKFDYAPTQ-SDEMGLRIGDTVLISKKVDAEWFYGENQnq---rTFGIVPS 244
gi 1346669    463 EALFSYEATQ-PEDLEFQEGDIILVLSKVNEEWLEGECKg-----KVGIFPK 508
gi 50403736   277 TAIYDYNSNE-AGDLNFAVGSQIMVTARVNEEWLEGECFg-----RSGIFPS 322
1VA7_A          7 EAAYDFPGSGsSSELPLKKGDIVFISRDEPSGWSLAKLLdg---sKEGWVPT 55
gi 325511390  162 RAIANYEKTS-GSEMALSTGDVVEVVEKSESGWWFCQMKa-----KRGWIPA 207
gi 1168809     36 IALYDFPGTQ-SSHLPLNLGDTIHVLSKSATGWWDGVVMgnsgelQRGWFPH 86
gi 341940635  265 YALYAFNGHD-SSHCQLGQDEPCILLNDQDAYWWLVKRItd---gKIGFAPA 312
gi 114914     161 IVLYDFKAEK-ADELTTYVGENLFICAHHNCEWFIAKPIgr--lgGPGLVPV 209
gi 730721     129 IVQFDFAAER-PDELEAKAGEAIIIIARSNHEWLVAKPIgr--lgGPGLIPL 177
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