1WIM,1FBV,2CKL


Conserved Protein Domain Family
RING

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smart00184: RING 
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Ring finger
E3 ubiquitin-protein ligase activity is intrinsic to the RING domain of c-Cbl and is likely to be a general function of this domain; Various RING fingers exhibit binding activity towards E2 ubiquitin-conjugating enzymes (Ubc' s)
Statistics
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PSSM-Id: 214546
View PSSM: smart00184
Aligned: 276 rows
Threshold Bit Score: 27.4734
Threshold Setting Gi: 75318467
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
1WIM_A         8 CKLCLGEYp-------------vEQMTTIAQ-CQCi-FCTLCLKQYVEllikegleTAISCPDA 56
gi 74763771  130 CQPCIRRP---------------CPPCIRKP-CIRr-PCQPCIRR--------------PCPPC 162
gi 75318315  209 CHQCLKGEr--------------ITLLICSE-CEKtmFCLQCIRKWYPnls--eddVVEKCPLC 255
gi 9627884   212 CNVCKEIStd------------erFLKPKEC-CEYa-ICNACCVNMWKta-----ttHAKCPAC 256
gi 151944783  33 CPLCIEPMdi------------tDKNFFPCP-CGYq-ICQFCYNNIRQnp-----elNGRCPAC 77
gi 18395478  155 CGICLEP-----------------CTKMVLPnCCHa-MCIKCYRNWNTks--------eSCPFC 192
gi 9630090    39 CAVCLETYcvqs--------nniIDFLMPSE-CTHl-FCYKCVLNMYKnamn-vpraAVSCPMC 91
gi 332471     86 CSVCLETYsqqs--------ndtCPFLIPTT-CDHg-FCFKCVINLQSnamn-iphsTVCCPLC 138
gi 9627831     8 CNICFSVAeiknyflqpidrltiIPVLELDT-CKHq-LCSMCIRKIRKr-------kKVPCPLC 62
gi 73972753  405 CIICSEY----------------FIEAVTLN-CAHs-FCSYCINEWMK--------RKVECPIC 442
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