Conserved Protein Domain Family
Esterase_lipase

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cl12031: Esterase_lipase Superfamily (this model, PSSM-Id:214205 is obsolete)
Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate.
Links
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Taxonomy: root
PubMed: 17 links
Protein: Related Protein
Related Structure
Statistics
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Accession: cl12031
PSSM Id: 214205
Name: Esterase_lipase
Created: 20-Jan-2010
Updated: 29-Oct-2012
Superfamily
Curated CD Hierarchy
cd00312::Esterase_lipase: single member domain hierarchy. Click the red icon to see the complete information for this domain model.
cd12806::Esterase_713_like: root of the domain hierarchy. Click the red icon to see the complete information for this domain model.
Imported CD
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