Conserved Protein Domain Family
RabL4

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cd04101: RabL4 
Rab GTPase-like family 4 (Rab-like4)
RabL4 (Rab-like4) subfamily. RabL4s are novel proteins that have high sequence similarity with Rab family members, but display features that are distinct from Rabs, and have been termed Rab-like. As in other Rab-like proteins, RabL4 lacks a prenylation site at the C-terminus. The specific function of RabL4 remains unknown.
Statistics
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PSSM-Id: 206688
View PSSM: cd04101
Aligned: 4 rows
Threshold Bit Score: 284.805
Threshold Setting Gi: 38224599
Created: 12-Jan-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
  next features
Feature 1:GTP/Mg2+ binding site [chemical binding site]
Evidence:
  • Comment:Based on sequence similarity to Rab family proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1               #######         #       ##                           #                  
gi 12653581   6 AKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVpvpdtgdSVELFIFDSAGKELFSEMLDKLWESPNVL 85
gi 38224599   6 LQIAVVGAPAVGKSAFVQMIHSNGMTFPRNYLMTTGCDFVVKEVqvd-denTVEMLIFDIAGQKEYETMVATHVEHAAAI 84
gi 62360653   6 LQVAVVGAPTVGKTAFVQMLHSNGTTFPKNYLMTLGCDFIVKEVpvd-ddnTVEMIIFDVSGQREYEPMVSSYLQNTAVF 84
gi 56269729   6 ARCVVVGDAAVGKSTLCQMFCSDGAVYQKNYTMNVGVELLEKTVpipdtsdSVELFIYDSAGRELFSDACENVWSQPSVV 85
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                            ## #                          ###          
gi 12653581  86 CLVYDVTNEESFNNCSKWLEKARSqapgisLPGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFH 165
gi 38224599  85 ILMYDVSNKVKFEACTRWMNALKHan--sgMIGFLIANKMDLVDKAEVTERQGTSLASANQMKFYKCSALRGVGVREPIE 162
gi 62360653  85 IVMYDVSNKVTFEACARWVNQVRTns--keSVGILIANKSDLSDKAEVTDRQGKDLANANKMKFYKISTLRGVGITEPID 162
gi 56269729  86 CVVFDVTSEASFNNCSRWIDRVQThshglhTPGVLVGNKCDLTSRREVDAAAAQAFAQTHTLQYHETSAKEIGHYEAPFL 165

                ....*..
Feature 1              
gi 12653581 166 CLAKQFH 172
gi 38224599 163 DIARLYV 169
gi 62360653 163 EIARHYV 169
gi 56269729 166 SLAAAFH 172

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