Conserved Protein Domain Family
BNR_2

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pfam13088: BNR_2 (this model, PSSM-Id:205269 is obsolete and has been replaced by 315701)
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BNR repeat-like domain
This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
Statistics
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PSSM-Id: 205269
View PSSM: pfam13088
Aligned: 78 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 23-Dec-2011
Updated: 5-Jan-2012
Structure
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Program:
Drawing:
Aligned Rows:
pfam13088 is not assigned to any domain superfamily.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B        33 QqsllAFAEQ----RA---------S----KKDE--H----AELIVLRRgdydapTHQVQ----WQAQEVvaq-arL--- 81
gi 281348088  89 Gt---LLAFA----EArk-----msT----SDEG--A----KFIALRRS------TDQGSt---WSPTAFivddgeT--- 134
gi 260828653  66 Gt---LIALCgarkYS---------S----RDDS--K----KVLAIRRSk------DKDKt---WLPTSFlvd-dgY--- 110
gi 260828651  69 Gt---LIALSgarkYS---------S----SDVD--R----KFLAIRRS------EDKGKt---WLPTEFlvddgyE--- 114
gi 260828655  68 Gt---ILALAgarkYS---------K----GDAG--K----KILALRRS------TDKGVt---WSPTAFlvd-dgY--- 112
gi 220914122  34 Gt---VLAAY----DG---------R----PNLD--DlpspIDLLIRRS------TDSGQt---WGGQEVvrsgtgL--- 79
gi 148372014  63 Gs---LLAFA----EA---------RkasqRDMG--Q----KFIAMRRSs----pSSSGPagltWSPTSFivddglA--- 113
gi 260593290  80 Gt---LLAVC----DYrlnhsdigwN----NRNGlwQ----INVVMKTSq------DFGRt---WSDSVCvargneHatn 135
gi 149177223  58 tgltrfkdQW----FC---------V----FRTG--K----AHVSPDGSlqv-lsSKDGKt---WKPVARiss------- 103
gi 71896602   82 Gt---LLAFA----EArk-----ksA----SDEG--A----KFIAMRRS------TDQGSt---WSSTAFivd-dgE--- 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B        82 -DGHRSMNPCPLYDAqT-GTLF-LFFIA---IPGQVTEQqqlqtRANvtr--------lcqVTSTDHGRTWSSPRdltdA 147
gi 281348088 135 -PD-GLNLGAVVSDMeT-GVVF-LFYSL---CAHKAGCQ-----VAStm-----------lVWSKDDGVSWSPPR----N 187
gi 260828653 111 -DTGVLGVGTVFADF-DsNTSF-VMFAH---CHYKCDVP-----ALLl-------------INSTDDGVTWGQPR----N 162
gi 260828651 115 -QGV-LFPGTMFADF-DsNTLF-VMFIH---CQLKCKVP-----ALLl-------------INSTDDGVTWGQPR----S 165
gi 260828655 113 -DKGVLGAGTAFVDD-DsNTTF-VMFIH---CQFRC--A-----VPSvl-----------lMNSTNDGVTWGQPR----N 164
gi 220914122  80 -EG--LGDPSLLVDAeT-GRIF-LFHAA---GTRAGFFE-----SATgmapddpaiqhtdlSWSDDDGVTWQHRRlt-aE 145
gi 148372014 114 -PD-GVNLGSVVVDE-E-KALIiLIYSL---HFHIST-------SAStm-----------mIESKTDGLSWSVPR----N 164
gi 260593290 136 pVRAAFGDPSIVADRtS-DNVL-LHCVA---GKSGYQTA-----TRQnpqh-------avfFHSKDGGKTWDNGI----E 194
gi 149177223 104 -etsDLRDAKISVTP-E-GQLM-LSGAAalpQPNPVKHQ-----SMN---------------WFSDDGTHWSKGY----K 155
gi 71896602  127 -ASDGLNLGAVVNDVdT-GVVF-LIYTL---CAHKV--------NCQvas--------tmlVWSKDDGVSWSPPRnlsvD 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B       148 A----IG---Payre-wstfAV----Gpg--hcLQL----Nd--rAR--------------SLVV--PayaYRklhpiQR 191
gi 281348088 188 L----SL---Dig-----teMF----ApgpgsgIQKqrepR----KG--------------RLIV--C---Ghg---tLE 225
gi 260828653 163 V----NPrtnGsr-----sfHP----Gpg--yaIRK----RlephKG--------------RFVV--C---AHgr--pQD 202
gi 260828651 166 I----SPrsnGsr-----sfHP----Gpg--ygIRK----RlephKG--------------RFVV--C---AHgr-pqDR 206
gi 260828655 165 I----TP---Qlqp----gvVS----HpspgygIRK----RyephKG--------------RWVV--C---Ahg---rAP 203
gi 220914122 146 L----KG---Ssp-----agRDvtgiFaaagqgIQI----HagpfTG--------------RLVQ--Q---FVll--cGG 188
gi 148372014 165 I----SG---Qig-----vqPF----ApgpgfgIQK----RydpaKG--------------RLVV--C---Ghg---tLE 202
gi 260593290 195 LtemiHG---Lyd-----gkLP----NggkpdgIFL----T----SGkimqsryirkakfyRLYIahP---IRqk--gVD 249
gi 149177223 156 I----GD---PsvwlwgmkwHN----Gdv--ysIGY----H----TGk------------------------------EG 184
gi 71896602  185 I----GT---Em-------fAP----Gpg--sgIQK----QrepwKG--------------RLIV--CghgTLe------ 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B       192 PiPSAFCFLSHDHGRTWARGHF-----------V-----------A---------------QDtLE--CQVAEv-eTGEq 231
gi 281348088 226 R-DGVFCLLSDDHGASWHYGSG-----------VsgipygqpkreNd--------------FNpDE--CQPYEl--PDG- 274
gi 260828653 203 KpRGITLLISDDGAKTWREGAF-----------V-----------Pdmpcre---npetknFWpGE--CQPVEl--HDG- 252
gi 260828651 207 P-RGITLLLSDDAAKTWREGAF-----------V-----------Pdgpcre----dpeekFWpGE--CQAVEl--ADG- 254
gi 260828655 204 E-WGLSLLLSDDGAITWRTGAF-----------V-----------YnrpcndtcgdshhttFQaGE--CQPVEl--PDG- 255
gi 220914122 189 E-IMAASAYSDNYGERWTLGEF-----------I-----------Sa--------------GThGAapNENKVtalDDG- 230
gi 148372014 203 G-DGVFCILSDDHGQSWRDGAVvksipfnrpkrP-----------Qd--------------FNpDE--SQPVEm--TDG- 251
gi 260593290 250 I-CGTFVIYSDDFGYTWHTLGN-----------Psv--------aPs--------------IAqDE--SKIEEl--PDG- 290
gi 149177223 185 P-RFTRLYKSSDGKDYETVVDK-----------L-----------Fd---------------TgYT--NESSLvftKDN- 223
gi 71896602  219 -rDGVFCLLSDDHGASWhyGTG-----------V-----------Sgipfgq---pkhdhdFNpd--ecQPYEl--PDG- 267
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B       232 rVVTLNARShl----rARVQAQ------STNDGLDF--Q------EsqlvkklVEpppqgcqgsVI---S----FPSP-- 284
gi 281348088 275 -SVVINARNqnnyhcrCRIVLR------SYDACDTI--R------P-------RD---------VTfdpE----LVDP-- 317
gi 260828653 253 -SILVMIRNrgrcscpCKAFMR------SYDGGQTL--P------Lhdl--yfAQ---------AL---I----EPTC-- 297
gi 260828651 255 -SLLVMTRNrgrcscpCKAFMR------SHDGGQTL--P------Lhdf--ffAR---------AL---I----EPTC-- 299
gi 260828655 256 -SLLVMTRNqlrctchCKAFLT------SHDGGETL--PisslrfD-------HT---------LI---E----PPtda- 302
gi 220914122 231 -RLLLHSRAt-----pRRLAAT------STDGGHSW--S------P-------LA---------PVe--D----LPDPsd 268
gi 148372014 252 -SIIINVRNqnnyhcrCRIVAR------SFDGGETL---------P-------VE---------HL---DfdytLVDPav 296
gi 260593290 291 -SVLLSCRNvyg-grrFNVFTYtnakeaTGSWGKEV--M------Pe-----nMT---------AK---E----VNAC-- 337
gi 149177223 224 -TCYCLLRRdak-ganTGLLGV------SRPPYTDW------------------E---------WK---D----LGVR-- 259
gi 71896602  268 -SVIINARNqnnyhcrCRIVLR------SYDACDTLrpR------DvtfdpelVD--------------------PVV-- 312
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1VCU_B       285 RS------------------GPGspAQWLLYThpth--swqRADLGAY---------LnpRPPa--PEAWS-EPVLLAKG 332
gi 281348088 318 VVaaga-----------vatSSG---IVFFSNpah---pefRVNLTLR---------W--SFSn--GTSWRkETVQLWPG 367
gi 260828653 298 QSgll-----------------yhrGVLFFSGpnt---ttgRHNMTLK---------W--SYDd--GTTWE-GELPIWNE 343
gi 260828651 300 QSgll-----------------yhrGVLFFSGpns---ttgRYNMTLK---------W--SYNd--GATWE-GELPIWNE 345
gi 260828655 303 -----------------glfYSD--GVLYFTGpns---sskRQKMMLK---------W--SYDn--GTSWA-GELPIWNK 346
gi 220914122 269 NGsltrfdglpsvmdyagtaTD---QWLLATNnrd---talRRNTVLG---------L--SPDn--GSTWP-AGLVLCAG 328
gi 148372014 297 aa---------------galQKD--GVLYFTNpah---elnRVNLTLR---------W--STTh--GRSWEdKTVHIWAG 343
gi 260593290 338 NGgili-----------vpaKRNidGKQLFVAlqsvplsakRDSVGFYykeiaryadY--STAaalGKNWK-KGLRVTDE 403
gi 149177223 260 IGgpdl-----------fqlPDG--RFLATVRlys-----pkAHTSIC---------Q--IDVe--KGTLT-ELLELPSG 307
gi 71896602  313 AAgala----------------tssGIVFFSNpah---peyRVNLTLR---------W--SFSn--GTSWQkERVQLWPG 360
                        490       500
                 ....*....|....*....|....*.
1VCU_B       333 S-CAYSDLQSMGTgp---dGspLFGC 354
gi 281348088 368 P-SGYSSLAALEGsvggkdeapqlyv 392
gi 260828653 344 M-AGYSVLTDDPT------D--DRHL 360
gi 260828651 346 M-AGYSVLAEDPT------D--DRHL 362
gi 260828655 347 A-AGYSAITMLQkdpedknflyvlye 371
gi 220914122 329 S-SAYSTATRLPD------G--NIGV 345
gi 148372014 344 Psgyssmtslesssiedqkfiyivye 369
gi 260593290 404 S-SCYSTMVNMSN------H--RIGF 420
gi 149177223 308 GdTSYANMVLH-D------G--LLNV 324
gi 71896602  361 P-SGYSSLTALENstdgkkQppQLFV 385
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