3L2O,2P1N,1NEX


Conserved Protein Domain Family
F-box
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pfam00646: F-box (this model, PSSM-Id:201368 is obsolete and has been replaced by 425796)
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F-box domain
This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.
Links
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Statistics
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PSSM-Id: 201368
Aligned: 473 rows
Threshold Bit Score: -1
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3L2O_B   3 STLTRLPiD------------------VQLYILSFLSPHDLCQLGSTNHYWNETVRDPILWRYFLL 50  human
Q83916   2 DLRSLLPdE------------------LWIEIFCYLTNKDIAKFVMCYNNMIELVKSSKFLCLYIK 49  Ovine adenovirus 7
Q9VFN3  73 AAIELLPnE------------------MWLEIMSYLSYNDLLQLRMVSWRCRDLVHRRRFMEKGKV 120 fruit fly
1NEX_B  13 DLITSLPfE------------------ISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLL 60  baker's yeast
Q9VMA6   2 ALIENLNdD------------------CVLKIVDYLDLEDQLKLWKSSEPASR-LRSLISYIWQRN 48  fruit fly
Q9XV32 269 MKCFRLSnEynnddkigsglqvlmtdlILRNILQHVGLTTILALRRVSWGVLNCIDRIKPDLKIEV 334 Caenorhabditis elegans
Q9XX06 190 FSIPDLNgPlrvf----------qnylIMEHVLEKLALGTIQALRRVSRGVRQVIDFLKPDSKICG 245 Caenorhabditis elegans
O17299 308 SAMLCLSnQl-----------------IMEKIVQHFDFADLAVLRKVSRGSRQCVDILKPDPKLVA 356 Caenorhabditis elegans
Q9TYZ7 313 LCTSELSiKvlh------------nglLMKNILSHLGRLDICRLRRTSRGVQKCVDIIKPDAEIIA 366 Caenorhabditis elegans
Q9TYZ8 323 SKVLQNAl-------------------LMKNILNHLERKDICRLQRTSRKIHESIANLKPDSKIVA 369 Caenorhabditis elegans
Q83916   2 DLRSLLPdE------------------LWIEIFCYLTNKDIAKFVMCYNNMIELVKSSKFLCLYIK 49  Ovine adenovirus 7
Q9VFN3  73 AAIELLPnE------------------MWLEIMSYLSYNDLLQLRMVSWRCRDLVHRRRFMEKGKV 120 fruit fly
1NEX_B  13 DLITSLPfE------------------ISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLL 60  baker's yeast
Q9VMA6   2 ALIENLNdD------------------CVLKIVDYLDLEDQLKLWKSSEPASR-LRSLISYIWQRN 48  fruit fly
Q9XV32 269 MKCFRLSnEynnddkigsglqvlmtdlILRNILQHVGLTTILALRRVSWGVLNCIDRIKPDLKIEV 334 Caenorhabditis elegans
Q9XX06 190 FSIPDLNgPlrvf----------qnylIMEHVLEKLALGTIQALRRVSRGVRQVIDFLKPDSKICG 245 Caenorhabditis elegans
O17299 308 SAMLCLSnQl-----------------IMEKIVQHFDFADLAVLRKVSRGSRQCVDILKPDPKLVA 356 Caenorhabditis elegans
Q9TYZ7 313 LCTSELSiKvlh------------nglLMKNILSHLGRLDICRLRRTSRGVQKCVDIIKPDAEIIA 366 Caenorhabditis elegans
Q9TYZ8 323 SKVLQNAl-------------------LMKNILNHLERKDICRLQRTSRKIHESIANLKPDSKIVA 369 Caenorhabditis elegans
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