2NZT,2NZT,3O1W


Conserved Protein Domain Family
Hexokinase_1

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pfam00349: Hexokinase_1 (this model, PSSM-Id:201171 is obsolete and has been replaced by 425627)
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Hexokinase
Hexokinase (EC:2.7.1.1) contains two structurally similar domains represented by this family and pfam03727. Some members of the family have two copies of each of these domains.
Statistics
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PSSM-Id: 201171
Aligned: 14 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NZT_A   3 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLG--ATTHPTAA-----VKMLPTFVRSTPDGTEHGEFLALDLGGT- 74   human
Q02155  28 ELSWRINKFVNQLRISYSTLEEFVDNFVYELKKGLEahRKHPNLWIphecsFKMLDSCIANIPTGQEKGTYYAIDFGGT- 106  malaria parasite P. ...
P52790  28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALR--GQASPAPA-----VRMLPTYVGSTPHGTEQGDFVVLELGATg 100  human
P17709  13 AVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAppKEGHTLASdk--gLPMIPAFVTGSPNGTERGVLLAADLGGT- 89   Saccharomyces cerevi...
P27595 465 EQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLR--KETNSNAT-----VNMLPSFLRSIPDGTEDGDFLALDLGGT- 536  cattle
2NZT_A 451 DQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLS--KETHASAP-----VKMLPTYVCATPDGTEKGDFLALDLGGT- 522  human
Q09756  26 TLQDHLDELEEQFTIPTELLHRVTDRFVSELYKGLT--TNPGD--------VPMVPTWIIGTPDGNEHGSYLALDLGGT- 94   Schizosaccharomyces ...
P50506  22 YLLKELTELEGLLTVSGETLRKITDHFISELEKGLS--KQGGN--------IPMIPGWVMDFPTGKEMGDYLAIDLGGT- 90   Schwanniomyces occid...
P04807  22 ELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLS--KKGGN--------IPMIPGWVMDFPTGKESGDFLAIDLGGT- 90   Saccharomyces cerevi...
P50521   4 NFQQAVKKLVNDFEYPTESLREAVKEFDELRQKGLQ--KNGEV--------LAMAPAFISTLPTGAETGDFLALDFGGT- 72   Schizosaccharomyces ...
2NZT_A  75 -NFRVLWVKVTDNGlqKVEMENQIYAIP-------EDIMRGSG---TQLFDHIAECLANFMDKLQI-------KDKKLPL 136  human
Q02155 107 -NFRAVRASLDGKG--KIKRDQETYSLKftgsyshEKGLLDKHataSQLFDHFAERIKYIMGEFNDl-----dNKEVKSV 178  malaria parasite P. ...
P52790 101 aSLRVLWVTLTGIEghRVEPRSQEFVIP-------QEVMLGAG---QQLFDFAAHCLSEFLDAQPV-------NKQGLQL 163  human
P17709  90 -NFRICSVNLHGDH--TFSMEQMKSKIP-------DDLLDDENvtsDDLFGFLARRTLAFMKKYHPdelakgkDAKPMKL 159  Saccharomyces cerevi...
P27595 537 -NFRVLLVKIRSGKksTVEMHNKIYRIP-------IEIMQGTG---EELFDHIVSCISDFLDYMGI-------KGPRMPL 598  cattle
2NZT_A 523 -NFRVLLVRVRNGKwgGVEMHNKIYAIP-------QEVMHGTG---DELFDHIVQCIADFLEYMGM-------KGVSLPL 584  human
Q09756  95 -NLRVCAVEVQGNG--KFDITQSKYRLP-------QELKVGTR---EALFDYIADCIKKFVEEVHPg------KSQNLEI 155  Schizosaccharomyces ...
P50506  91 -NLRVVLVKLGGNR--DFDTTQSKFALP-------ENMRTAKS---EELWEFIAECLQKFVEEEFRn-----gVLSNLPL 152  Schwanniomyces occid...
P04807  91 -NLRVVLVKLGGDR--TFDTTQSKYRLP-------DAMRTTQNp--DELWEFIADSLKAFIDEQFPq-----gISEPIPL 153  Saccharomyces cerevi...
P50521  73 -NLRVCWIQLLGDG--KYEMKHSKSVLP-------RECVRNESv--KPIIDFMSDHVELFIKEHFPskf-gcpEEEYLPM 139  Schizosaccharomyces ...
2NZT_A 137 GFTFSFPCHQTKLDESFLVSWTKGFKS-----SGVEGRDVVALIRKAIQRRGDFdIDIVAVVNDTVGTMMTCGYDD 207  human
Q02155 179 GFTFSFPCTSPSINCSILIDWTKGFETgratnDPVEGRDVCKLMNDAFVRAAIP-AKVCCVLNDAVGTLMSCAYQK 253  malaria parasite P. falc...
P52790 164 GFSFSFPCHQTGLDRSTLISWTKGFRC-----SGVEGQDVVQLLRDAIRRQGAYnIDVVAVVNDTVGTMMGCEPGV 234  human
P17709 160 GFTFSYPVDQTSLNSGTLIRWTKGFRI-----ADTVGKDVVQLYQEQLSAQGMPmIKVVALTNDTVGTYLSHCYTS 230  Saccharomyces cerevisiae...
P27595 599 GFTFSFPCQQTSLDAGILITWTKGFKA-----TDCVGHDVVTLLRDAVKRREEFdLDVVAVVNDTVGTMMTCAYEE 669  cattle
2NZT_A 585 GFTFSFPCQQNSLDESILLKWTKGFKA-----SGCEGEDVVTLLKEAIHRREEFdLDVVAVVNDTVGTMMTCGFED 655  human
Q09756 156 GFTFSYPCVQRSINDASLVAWTKGFDI-----DGVEGESVGPLLSAALKRVGCNnVRLNAILSDTTGTLVASNYAS 226  Schizosaccharomyces pomb...
P50506 153 GFTFSYPASQGSINEGYLQRWTKGFDI-----EGVEGHDVVPMLQAAIEKRKVP-IEVVALINDTTGTLVASMYTD 222  Schwanniomyces occidentalis
P04807 154 GFTFSFPASQNKINEGILQRWTKGFDI-----PNIENHDVVPMLQKQITKRNIP-IEVVALINDTTGTLVASYYTD 223  Saccharomyces cerevisiae...
P50521 140 GFTFSYPANQVSITESYLLRWTKGLNI-----PEAINKDFAQFLTEGFKARNLP-IRIEAVINDTVGTLVTRAYTS 209  Schizosaccharomyces pomb...
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