3LI6,1YX7,1V1G,1Y1A,3PM8,1S6I,3PM8,3K21,1S6I,2ROB,1PVA,2KQY,5PAL,1OQP,1KSM,2WCE,2WOR,2KAY,2JPT,1PSB,1XK4,3PM8,3K21,1S6I,2KLE,1SL8,1JBA,2JU0,2L2E,1NYA,1SL8,2JXC,1S6I,1L2O,1PON,3PM8,1OQP,1O1F,1YX7,3K21,1SCM,1M8Q,1N2D,1M8Q,5PAL,1PVA,2KYC,1Y1A,1UHN,1V1G,1JBA,2JU0,2L2E,1OMV,3LI6,1K95,2JU0,1JBA,1OMV,2L2E,1UHN,1V1G,1NYA,1K95


Conserved Protein Domain Family
efhand

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pfam00036: efhand (this model, PSSM-Id:200946 is obsolete and has been replaced by 333786)
Click on image for an interactive view with Cn3D
EF hand
The EF-hands can be divided into two classes: signaling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. These proteins typically undergo a calcium-dependent conformational change which opens a target binding site. The latter group is represented by calbindin D9k and do not undergo calcium dependent conformational changes.
Statistics
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PSSM-Id: 200946
View PSSM: pfam00036
Aligned: 908 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20
                 ....*....|....*....|....*....
3LI6_D         1 MAEALFKEIDVNGDGAVSYEEVKAFVSKK 29
gi 74956561  357 GLLNEFKKIDKDGNGQISKDELLQVYMKQ 385
gi 74964866   22 RLTRRFKKLDVDGSGSLSVEEFMSLPELQ 50
gi 1345659    22 RLGKRFRKLDLDNSGALSIDEFMSLPELQ 50
gi 115854     22 RLGRSFKKMDLDKSGSLSVDEFMSLPELQ 50
gi 12229753   22 RLGKSFRKLDLDKSGSLSIEEFMRLPELQ 50
gi 1168750    29 KLYKRFKKLDKDGNGTISKDEFLMIPELA 57
gi 115495     25 RLRKRFMKLDRDSSGSIDKNEFMSIPGVS 53
gi 12643541  570 DLEIIFNAIDTDHSGLISVEEFRAMWKLF 598
gi 229462735 656 NLETIFRIIDSDHSGFISLDEFRQTWKLF 684
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