1I4O,1JD6,2VM5,2UVL,3CLX,3M0A,1SDZ,2QRA,2RAW


Conserved Protein Domain Family
BIR

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smart00238: BIR 
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Baculoviral inhibition of apoptosis protein repeat
Domain found in inhibitor of apoptosis proteins (IAPs) and other proteins. Acts as a direct inhibitor of caspase enzymes.
Statistics
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PSSM-Id: 197595
View PSSM: smart00238
Aligned: 38 rows
Threshold Bit Score: 75.8168
Threshold Setting Gi: 419123
Created: 12-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1I4O_C      43 SEEARLKSFQ-NWPDYAHL-TPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFP----NCFFVLG 113
gi 2134780  25 EEFNRLKTFA-NFPSGSPV-SASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP----NCRFING 95
gi 2497236  28 CELYRMSTYS-TFPAGVPV-SERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYP----SCRFVQS 98
gi 419123  130 NLQSRMDTFVnFWPaALRD-MITNIAEAGLFYTGRGDETVCFFCDCCVRDWHTNEDTWQRHAAENP----QCYFVXS 201
gi 2497245 125 HPSARRATFD-HWPaALNA-LTHDIAEAGMFHTMLGDETACFFCDCRVRDWLPGDDPWQRHALANP----QCYFVVC 195
gi 1353180  36 SYDERLNSFQ-NWPiQLLP-SKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRSDNPFEEHKKHTQdlkiNCLFVKS 110
gi 419123   28 MLIERHSSFE-NYP-IENTaFINSLIVNGFKYNQVDDHVVCEYCEAEIKNWSEDECIEYAHVTLSP----YCAYANK 98
gi 2497247  28 SVDARNQSFA-----IHDIkNYEKFSNAGLFYTS-PTEITCYCCGMKFCNWLYEKHPLQVHGFWSR----NCGFMRA 94
3M0A_D       4 CELYRMSTYS-TFPAGVPV-SERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYP----SCRFVQS 74
2QRA_D      37 eEFNRLKTFA-NFPSGSPV-SASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP----NCRFING 107
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