Conserved Protein Domain Family
DUF3546

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pfam12066: DUF3546 (this model, PSSM-Id:192930 is obsolete and has been replaced by 314875)
Domain of unknown function (DUF3546)
This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 93 to 114 amino acids in length. This domain has two completely conserved Y residues that may be functionally important.
Statistics
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PSSM-Id: 192930
View PSSM: pfam12066
Aligned: 19 rows
Threshold Bit Score: 99.7784
Threshold Setting Gi: 145354829
Created: 30-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q66I22 155 TFKEFLIS-LDDSVDETESVKRYNEYKIDFRRQQMQDFFlaHKDEEWFRSKY--HPDEAGRRKAEAHSALQNRLGVYMYL 231  zebrafish
Q966L5  86 TFKKFLTS-QEDDISEEDAIKKYNEYKTEHRKHQLERFFraHKDEEWFRLKY--KPDDAKKLREAHLENVQKRLQVFNEL 162  Caenorhabditis elegans
Q4UHD3  28 NFKHFVAL-KEDQISPEKAFQEYSKYLLDFLNNEITLYFdkYEHLPFFLEKF--HPYYLEKGFELSRAS-------FLNN 97   Theileria annulata
Q5CXB1  51 TFKQFTLS-QDDNLAPNELIEMYDSYKTKYVQKHQLEFLenNRNSPLILEKF--HPIWIRKIIDERRNLVLKRIEVFSLK 127  Cryptosporidium parvum
Q5Z4U6 196 TYKQFIQV-LEDDISPAEAEKRYQEYRTEYITTQKRAYFdlNKNDDRLKDKY--HPTNLSSVIDRRNDSCKATAKDFFHD 272  Oryza sativa Japonic...
Q6Z422 204 TYKQFTQK-LEDDVSPGEAESRYQEYKTSYITSQKQDYFdhHKNEDRLKDMY--HPTNLLSVIERRNELCKAAAKNLILD 280  Oryza sativa Japonic...
Q24BY2  78 NFRQFMEL-QTDRVDTHKAETHYQYYKKHWEKRQNEIFVkeHMEEAWFKEKY--DPIISEEIQKDRLSECKKTAEKFIED 154  Tetrahymena thermoph...
A0E2A3  67 SFDQFQELyVSNDIPTEKLRLLYQTYERKWENKQKELFFdqHKDEPWIQDKY--NPVNRREFQEERNQLAQNRFNEFLKQ 144  Paramecium tetraurelia
Q5KD43 170 ESGQATEQ---EAKEKVGMAKRYERYRKEFTSRQLYALFltHRDSAWFKEKYlhFPEYVALRRRLNRQGRIPQVAQYISE 246  Cryptococcus neoformans
Q7SEL2 204 RVRGPEE----REKEKAKIQAAYDAYKEELQAKMAQTFVkqHKDEQWFRERY--VPEIRDGFRKQLNEFRRGAYTQWEQD 277  Neurospora crassa
Q66I22 232 MDNNWFESVSLDIERApqitKILDAAVIKMEGGAEND 268  zebrafish
Q966L5 163 KEQGQFNKFSLDFGDAeaiiRMLDSVVVKLENGTEDE 199  Caenorhabditis elegans
Q4UHD3  98 FESGKFNELLLEISYK------------RLYGKSSSD 122  Theileria annulata
Q5CXB1 128 LKRGGFSTVNKTNNDV----EKIGCEITITDTSHTNE 160  Cryptosporidium parvum
Q5Z4U6 273 LQNGTLD----------------------LGPGITAA 287  Oryza sativa Japonica Group
Q6Z422 281 LRSGTLD----------------------LGPGMTAG 295  Oryza sativa Japonica Group
Q24BY2 155 YKNNVFNSICLEITEN----KIQEIKSVENNEEDQEE 187  Tetrahymena thermophila SB210
A0E2A3 145 YNMGGFNNINLTMT------EMQLMDFFELNDHFYND 175  Paramecium tetraurelia
Q5KD43 247 LRSGAHDHVSYD--------QIEDVPGVKLDEDEPEG 275  Cryptococcus neoformans
Q7SEL2 278 LETGTFDDFSLEGIPKs--eSNGAGGVVEKEEGEATA 312  Neurospora crassa
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