Conserved Protein Domain Family
LIM_DA1
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cd09396: LIM_DA1 
The Lim domain of DA1
The Lim domain of DA1: DA1 contains one copy of LIM domain and a domain of unknown function. DA1 is predicted as an ubiquitin receptor, which sets final seed and organ size by restricting the period of cell proliferation. The LIM domain is 50-60 amino acids in size and shares two characteristic zinc finger motifs. The two zinc fingers contain eight conserved residues, mostly cysteines and histidines, which coordinately bond to two zinc atoms. LIM domains function as adaptors or scaffolds to support the assembly of multimeric protein.
Links
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Statistics
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PSSM-Id: 188782
Aligned: 29 rows
Threshold Bit Score: 56.107
Created: 4-Oct-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding site
Feature 1:Zn binding site [ion binding site]
Evidence:
  • Comment:The two zinc fingers contain eight conserved residues, mostly cysteines and histidines, which coordinately bond to two zinc atoms. The Zn binding residues of LIM domain are highly conserved.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         #  #                 #  #  #  #                    #  # 
XP_002278137  430 CAGCGTEIilrryLKCIGKVWHPECFRCHACKHPISd--yEFFLSGe-SPYHKSCY 482  wine grape
XP_001728797  536 CQACKKPVgd-ehVQALRAVWHPECFVCTRCRKPCQga-tFVAPDG--SPCDFDCY 587  Malassezia globosa CBS 7966
XP_762559     978 CNGCKKPVlg-dlISALRAKWHPECFTCCSCDKPFEd--tMFFVKDg-RPYDEACY 1029 Ustilago maydis 521
NP_490764      90 CHACKLPTfe-rcVSAFNVHWHMACFKCKACRHPIKg--qEYVVHQg-CAYDEDCY 141  nematode
NP_497801     125 CAGCMETLvd-tcLLALDRHWHPRCFTCSSCNRPLPn--gEFYLVDd-KPYDLDCH 176  nematode
EEH53971      220 CPGCERSTawtggISAMGRTWHPTCFTCAGCRRVIAe--pSFATRDg-VAYHKSCF 272  Micromonas pusilla CCMP1545
BAB10937      201 CDGCKSAIeygrsVHALGVNWHPECFCCRYCDKPIAm--hEYKEHP--FWKEKYCP 252  thale cress
NP_201463     286 CGGCNFAVehggsVNILGVLWHPGCFCCRACHKPIAihdiENHVSNsrGKFHKSCY 341  thale cress
NP_197291    1240 CKDCKSAIedgisINAYGSVWHPQCFCCLRCREPIA----MNEISDlrGMYHKPCY 1291 thale cress
EEY56448      543 CGGCGLVLeg-eaVGALNQYFHYECFKCSYCSRVIAed-dGYAEKDn-QAFHQGCY 595  Phytophthora infestans T30-4

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