Conserved Protein Domain Family
CpaE_hom_Actino

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TIGR03815: CpaE_hom_Actino (this model, PSSM-Id:163527 is obsolete and has been replaced by 274798)
helicase/secretion neighborhood CpaE-like protein
Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins. Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.
Statistics
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PSSM-Id: 163527
View PSSM: TIGR03815
Aligned: 15 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 6-Mar-2012
Updated: 8-Mar-2012
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
YP_483371     41 GVSMTVAAEMSAVRRNWTSAPLVIVGMDEVEPCIAATLPDRRH-VVLVGGHVDDGRV----WDASVRIGADHVVFLPEAE 115 Frankia sp. CcI3
YP_873741     59 GTELDVAPDLVAARDRWTDAPLIILDAAQVTDQVARSLPRRPA-VVLVVQGEPAMDA----WQRAVVVGAEHIAALPTAE 133 Acidothermus ce...
YP_001625895  42 GAQLVHQVPPETAVAAVLIGPDVLMD----RRKVAEILSHQSCpLILVGHSLAESAL----WANAARELIHHVVSLPEGT 113 Renibacterium s...
YP_001160848  35 GVEVDLAPDPVAARSRWSPAPLVLVGSDQAQPCLRARLPHRRR-LVLVGHAGHLDPG----RDVADLMGAEFVAVLPAAE 109 Salinispora tro...
YP_288190     30 NVDVTVVSSAARSSRYWAQAPLVVVGTDLVGVLARAEPPRHAH-AVVVSRTPLSPALdfsvYPDAMRIGARDVLVLPDAE 108 Thermobifida fu...
YP_716694     39 GVTTTVATEPGALRRAWAAAPLVVVGMDRAEACIAAGLPLRPH-VVLVGGHVEDGRV----WSAGTRIGADHVIFLPEAE 113 Frankia alni AC...
YP_921593     25 GVTPDVASDGGAALRGWARAPVVLLGADMAEDLARISPPRRPR-VYVVSWAAVPDEM----FRVAVAVGAESVAQVARSE 99  Nocardioides sp...
NP_599552     30 GRPVIETTNLMDISRHFHRTSAVLIDASMASQL---SPGKRRD-RVFLLDSDPGPSD----WKTAMKIHAEQAMLLPAQA 101 Corynebacterium...
YP_001102640  42 GCDLDRAPDPLSVGDRWRTAPLVLLDGPAAEAGVANGLPRRPR--VLVLARAPGGDL----YRAAFHIGAEQEVILPAHE 115 Saccharopolyspo...
YP_832848      5 GGQLRVAADATEAAPFWDTAAVVLVGSD-----IRELPPRRRApAVLVGLGGEGDSL----WHLAAALGAERVAVLPDAA 75  Arthrobacter sp...
YP_483371    116 PWLVDLLSD-LD--GLDRhRSVTLGIIGGRGGTGASTLAVSLALAGLRHDLRTMLIDADPHGGGLApaftrlVPSMSGAF 192 Frankia sp. CcI3
YP_873741    134 PWLSEQLAD-VL--EGPP-RAVSVAITGVVGGCGATTLAAGLATVAGRHGIRTALVDADPWGGGID------LLFGGEGA 203 Acidothermus ce...
YP_001625895 114 AWLAEFLNT-L---QDRTeRGSVVAVIGGCGGAGASTAAGLLALKASREKIRTLLVDADPWGFGLE------GALSSDPV 183 Renibacterium s...
YP_001160848 110 PWLVDRFVE-CGpeQPDPvAARVVAVLGGRGGAGASVLAGGLAVTAARARLRTLLVDADPLGGGLD------LVLGWEQL 182 Salinispora tro...
YP_288190    109 QQLVALLTE-ST--DHAGeEALVVSVIGGRGGAGASLLAAALALAGHRAGLRTALVDADPLGGGLD------ILLGAEHV 179 Thermobifida fu...
YP_716694    114 LWLIDAFRD-LD--RSDPrASVTIGVVAGRRGSGASTLAVSLALAGLRHGLRTMLIDADPRGSGVApgfarlLPTAADPP 190 Frankia alni AC...
YP_921593    100 GWLTELLTD-LG--EAAPaEGLVVGVVGGSGGAGATTFACALGQVGARRG-RAVVIDADPLGPGID------RVLGLEDR 169 Nocardioides sp...
NP_599552    102 GELLSALGR-DDk-QLPVaSGHVIGVAGVVGGTGASTFAAALAKRRAES-VTTVLIDADPSSGGID------LLLGIEDV 172 Corynebacterium...
YP_001102640 116 GHLIELLAEaVD--RSAPrSGRVLAVIGGSGGAGASVLATGVAVTAARRGQRSLLLDCDPLGGGLD------LAVGAEST 187 Saccharopolyspo...
YP_832848     76 AWLAEYLSR-S---RSPEaGGLVLGVTGGCGGAGATTASIWIAQAAAEWGARVLLIDGDPWGGGLE------LALAAEES 145 Arthrobacter sp...
YP_483371    193 PGGetsslaplfptR----------HDQHDQMDgsGPVGPIAWSDRLPR-R----GDLSVVSWDPAV---S-PA--VPPA 251 Frankia sp. CcI3
YP_873741    204 RGL-----------R----------WADLTGAE--GRLPAGALRDQLPR-L----DDLVVLSHSPSR---F-TA--MSEP 249 Acidothermus ce...
YP_001625895 184 EGL-----------Q----------RHELSQSV--GVLNSQQFSAALPE-I----AHCSVLGFGRAA---Q-AAqqLNPA 231 Renibacterium s...
YP_001160848 183 GGL-----------R----------WPALTDAD--GRVDASSLVRALPS-R----GDLVVLSWDRGD---L-RL--LPAV 228 Salinispora tro...
YP_288190    180 PGS-----------R----------WEEFSNRQ--GRMLWPALRDSLPH-I----HGLPVVTWTRHG---P-YAp-IPPQ 226 Thermobifida fu...
YP_716694    191 PGD-----------VdrqstvppssPDAVSRRRl-GAAPLPSWPGPPAG-P----GDLAVVSWDLEV---G-PE--VPVG 247 Frankia alni AC...
YP_921593    170 HGV-----------R----------WDGLCQTT--GRLSARALREALPR-R----EQLGVLTWHAGE---P-AA--LQAF 215 Nocardioides sp...
NP_599552    173 PGA-----------R----------WPDVGLRR--GTVQAADVLKALPStP----DEVVVLSTARSNildP-FA--LSES 222 Corynebacterium...
YP_001102640 188 DGV-----------R----------WSGLSVSG--GRVAAGALHDALPQ-RrvgsGSLAVLACDRDG---PsSG--LTPQ 238 Saccharopolyspo...
YP_832848    146 PGL-----------R----------WTDLSEAS--GTIDPEQLSDALPV-A----GGFSFLSWPGSRe-rQ-KG--VEAA 193 Arthrobacter sp...
YP_483371    252 TMATLLA---TARCTSDLVILDLPGRGNPA-------ATAvdagttvALRTCQTVLIVTPADLPSIVAAERVCSAAIRRs 321 Frankia sp. CcI3
YP_873741    250 VVPQVIG---ALSRCNDLLVFDLPRYECGQasaaapaPPR-------SFPDSEVTLAVVPDDVRGIAAARAFLPRLGGR- 318 Acidothermus ce...
YP_001625895 232 LVIEVLE---AARRAFELIVIDVGRMVKSL--------ET-------FCESADQVLCLVPAAVPAMLSVHRMLPMVPRS- 292 Renibacterium s...
YP_001160848 229 AMAATLD---AARRARDVVVVDLPRHLDDA-------AVT-------ALQSVDRAFVVVPAELRATAAAARVVSAAAPHc 291 Salinispora tro...
YP_288190    227 AMRTVLH---AATRGCQMLVVDLPRALDAA-------AEE-------VLRRTTVALMILPAEVSAVVAAERLLPALRDSv 289 Thermobifida fu...
YP_716694    248 TMVTLLS---TAQATSDLVVVDLPWQQDPA-------AAL-------ALGSCRTALVVLRADLASVLAAERVCAMVGRRc 310 Frankia alni AC...
YP_921593    216 AVREVLS---AARRGHDLVVVDLPRTAGPL-------VDE-------VVARCDRLLVVVVPTVAGVASAVRTCARHPDPt 278 Nocardioides sp...
NP_599552    223 DVSAAIDcflSADRSVD-VVVDLPHARVH---------PD-------IAERLSHLVLVIPAEVRAVAAARARCLELQQLh 285 Corynebacterium...
YP_001102640 239 AVGAVVD---AGRRAGQTVVCDLPRHLSEA-------ALA-------GLRKADLTLVVVAAEVRACAAAARLVAEIRDRt 301 Saccharopolyspo...
YP_832848    194 TVGGVLD---AARRGYELVLVDIGRGTEPL--------RT-------FAWDCDRILMVAPAQLKAAVSSARLLQELPPVe 255 Arthrobacter sp...
YP_483371    322 a-dVRAVVRLHPsDRLTPEAIATMLGVPLAGVIssRRHRSVPTRDRYGGS-----ADRNTIDRLSEELLTRL 387 Frankia sp. CcI3
YP_873741    319 ---VWVVTRRRT-AALSGPEIAGLLGVPWLGEV--RHEARLVAAAQRGEApg--aSGMGALARLCAHLLQRI 382 Acidothermus cellulolyt...
YP_001625895 293 ---TKLVVRRPApEGLDAELIAESLGLPLVGEM--PKLRGVSTAAAQGRLsd--cASNRELGKLFSQTLSTL 357 Renibacterium salmonina...
YP_001160848 292 a-dLSLIVRGPApGRLKPTELARTLGLPLAGTV--RLEPALGRGLERGQApa--aDGRGPLAALCQRLLNEL 358 Salinispora tropica CNB...
YP_288190    290 a-dLRLVVRGATpDILSAESVASSLKLPLAGDL--PDDTELPRLLDQGELpt--rRTRSPLVAFSEAFVAHL 356 Thermobifida fusca YX
YP_716694    311 p-dVRAVVRQRQsAGLAPVAVSEMLGVPLAGVI--ADARQPGAATSAGADaprdaDAPGPLGdrllarlglr 379 Frankia alni ACN14a
YP_921593    279 --gVRLVLRG---AGIDPRAVSRATGISVLTTM--PDQRGLGEALDLGLGpv--rSRRAALGRAATEVLDQL 341 Nocardioides sp. JS614
NP_599552    286 v-sITCVLRHRGwSGLDVAEVEEILGADITAEV--GSIQRLAKSVEMHGLt---gSLPRVLSSACDAVLGEV 351 Corynebacterium glutami...
YP_001102640 302 agrLRLVVRGPAsSGLRVSDVGRAVGVEVLTAV--RPQTGLSTALDRGGFcatraGLRRTVERAASEVLRAL 371 Saccharopolyspora eryth...
YP_832848    256 ---TALVIRGKAgAVLDGPLIAESVGLPLQGLV--PEVKGTASATELGRLle--mGRRRSVRRFAASVLDLL 320 Arthrobacter sp. FB24
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