Q8RXC2 889 SFSLKERCAAVDTVSLVARVLHKSKAHLQSMLMSRNGSL---------VEDFFGQ------------LVGS-VPDLTEHL 946 thale cress Q012F3 685 LYGLKERGIAIESLARVADEFKRIKSRVKRSLPLKDAAS---------ADRFYSH------------TVAA-VEDLREHV 742 Ostreococcus ... Q7QF78 638 LYGLQKRIVASESCVTLVAQFRQMESYLGGLLGGGATDGgedgwtqgaLHEYLAR------------TGEY-VPDVRKPI 704 Anopheles gam... Q16RR9 705 MYGLQKRIVAAESCLSLINQFRLMEEYLSGLLSQQSSDAte------qLRRYLVE------------TAEC-VADVRKPI 765 yellow fever ... Q18602 699 LYGACERIIAVNSIEFVARQLDLIRPVIESLLLEDTREHls-----tiLDAFYTQ------------VLPC-QADARILI 760 Caenorhabditi... Q4RKF9 63 LYGLAQRVVATESLVFLAEQFESLQAHLDAMMPSAKKPF---------LQQFYSQaifkhdsffseeTVST-ASELRKPI 132 spotted green... Q54MU4 880 FFNLPVRMVAIESLSFIAEALIVCRPLFEQLLPPNQTDN---------INEFYNS------------IIGI-IPGLQGHL 937 Dictyostelium... Q54NV0 913 LYGLENKIIGLESMMFLVDCIMEAQPLVLDLIPNEKIMQ---------ISNFYVE------------TVSV-VASLRNLC 970 Dictyostelium... XP_001634515 244 MFGLAERILATESLVFLAKQFEFLHGPLEAIIPSNKRAF---------LSQFYSQ------------TVST-APEIRRPI 301 starlet sea a... XP_001419490 81 LYGLKERGIALESLSRVADEFKRIKARVKRSLPLKDAAL---------ADRFYSH------------TVAA-VDDLREHV 138 Ostreococcus ... NP_611258 701 LYGLSQRIVAVEAGRSMLQQFNVLQHYLNHLLPLAERPI---------LASYL-D------------YSDY-IADLAKLV 757 fruit fly XP_001317963 562 LRTLDQASAASDNMKGVAWYLRSVRSFIEESLPENSLGA---------LRRFFSD------------VVSIfLQSFASFC 620 Trichomonas v... Q012F3 685 LYGLKERGIAIESLARVADEFKRIKSRVKRSLPLKDAAS---------ADRFYSH------------TVAA-VEDLREHV 742 Ostreococcus ... Q7QF78 638 LYGLQKRIVASESCVTLVAQFRQMESYLGGLLGGGATDGgedgwtqgaLHEYLAR------------TGEY-VPDVRKPI 704 Anopheles gam... Q16RR9 705 MYGLQKRIVAAESCLSLINQFRLMEEYLSGLLSQQSSDAte------qLRRYLVE------------TAEC-VADVRKPI 765 yellow fever ... Q18602 699 LYGACERIIAVNSIEFVARQLDLIRPVIESLLLEDTREHls-----tiLDAFYTQ------------VLPC-QADARILI 760 Caenorhabditi... Q4RKF9 63 LYGLAQRVVATESLVFLAEQFESLQAHLDAMMPSAKKPF---------LQQFYSQaifkhdsffseeTVST-ASELRKPI 132 spotted green... Q54MU4 880 FFNLPVRMVAIESLSFIAEALIVCRPLFEQLLPPNQTDN---------INEFYNS------------IIGI-IPGLQGHL 937 Dictyostelium... Q54NV0 913 LYGLENKIIGLESMMFLVDCIMEAQPLVLDLIPNEKIMQ---------ISNFYVE------------TVSV-VASLRNLC 970 Dictyostelium... XP_001634515 244 MFGLAERILATESLVFLAKQFEFLHGPLEAIIPSNKRAF---------LSQFYSQ------------TVST-APEIRRPI 301 starlet sea a... XP_001419490 81 LYGLKERGIALESLSRVADEFKRIKARVKRSLPLKDAAL---------ADRFYSH------------TVAA-VDDLREHV 138 Ostreococcus ... NP_611258 701 LYGLSQRIVAVEAGRSMLQQFNVLQHYLNHLLPLAERPI---------LASYL-D------------YSDY-IADLAKLV 757 fruit fly XP_001317963 562 LRTLDQASAASDNMKGVAWYLRSVRSFIEESLPENSLGA---------LRRFFSD------------VVSIfLQSFASFC 620 Trichomonas v...
Q8RXC2 947 HRTTARILLHVN-------------GYVDRIANSKWEIKEL-GMEHNGYVDLMLGEFKHYKTRL-----AHGGIPQE--V 1005 thale cress Q012F3 743 YKNVASLLLNIGfcaeaigdgdpnfALVNSTFAGKYNLREA-PKRQSKWVDDVSAELLQFTTKL-----AVADVAPE--A 814 Ostreococcus ... Q7QF78 705 FMCSTARVIDLQ-------------AVLNAMAKVKWDVNHV-NVQHSPYIDTINRGIQYFAMKLee-qtSTVMLPPD--- 766 Anopheles gam... Q16RR9 766 YMCVTARVVDIQ-------------NVLHAMGKVKWDINHV-NVQHSSYVDTINRGVQHFAMRLeelsgQQANIPKE--- 828 yellow fever ... Q18602 761 VDASASRSLRLK-------------SLIDSVTSVKWDIGEL-RSEHNAYVDLLVQDYELFSIRIta-ikETAPVNLSeaM 825 Caenorhabditi... Q4RKF9 133 YWIVAAKAIDYE-------------QMLLLMAGVKWDIREI-MSQHNVYVDVLLKEFEQFNKRLad-vsRHVRIPLP--V 195 spotted green... Q54MU4 938 IKCTISAIFTHQas---------pqYFSNTISNIKWDMKIS-NPGKSSYVDAFIKEFTIFFNGLdkcvaNSTQFTDTpvI 1007 Dictyostelium... Q54NV0 971 YKNITSQFLNLE-------------NIPNLISSIKWELKEApTTESNSYTIPIIIEFHRFTGLLdeissKSSLITPK--I 1035 Dictyostelium... XP_001634515 302 YRAVATRCIGYE-------------KTLQLMTTVKWDIKEI-MSQHNAFVDILVREFQVFSMRLtq-lsKRIPVPKE--A 364 starlet sea a... XP_001419490 139 YKNVASLLLNIEfcaeaigdgdpnfALVNSTFVGKYNIRET-PSRHNKWVDDVQAELLQFTTKL-----ACADVAPE--A 210 Ostreococcus ... NP_611258 758 YTCVTSRVIDLS-------------SILAQMAKVKWDVNHV-IHQHSNYSDVLNRNIQSFAMCLee-iaKEVPVPSK--- 819 fruit fly XP_001317963 621 FPFFGPSMVNLT-------------EFDTQVKNTKWTINEP-PLDPHPFTKLWTENVSSFVKQVde-mkLAQDHKDE--I 683 Trichomonas v... Q012F3 743 YKNVASLLLNIGfcaeaigdgdpnfALVNSTFAGKYNLREA-PKRQSKWVDDVSAELLQFTTKL-----AVADVAPE--A 814 Ostreococcus ... Q7QF78 705 FMCSTARVIDLQ-------------AVLNAMAKVKWDVNHV-NVQHSPYIDTINRGIQYFAMKLee-qtSTVMLPPD--- 766 Anopheles gam... Q16RR9 766 YMCVTARVVDIQ-------------NVLHAMGKVKWDINHV-NVQHSSYVDTINRGVQHFAMRLeelsgQQANIPKE--- 828 yellow fever ... Q18602 761 VDASASRSLRLK-------------SLIDSVTSVKWDIGEL-RSEHNAYVDLLVQDYELFSIRIta-ikETAPVNLSeaM 825 Caenorhabditi... Q4RKF9 133 YWIVAAKAIDYE-------------QMLLLMAGVKWDIREI-MSQHNVYVDVLLKEFEQFNKRLad-vsRHVRIPLP--V 195 spotted green... Q54MU4 938 IKCTISAIFTHQas---------pqYFSNTISNIKWDMKIS-NPGKSSYVDAFIKEFTIFFNGLdkcvaNSTQFTDTpvI 1007 Dictyostelium... Q54NV0 971 YKNITSQFLNLE-------------NIPNLISSIKWELKEApTTESNSYTIPIIIEFHRFTGLLdeissKSSLITPK--I 1035 Dictyostelium... XP_001634515 302 YRAVATRCIGYE-------------KTLQLMTTVKWDIKEI-MSQHNAFVDILVREFQVFSMRLtq-lsKRIPVPKE--A 364 starlet sea a... XP_001419490 139 YKNVASLLLNIEfcaeaigdgdpnfALVNSTFVGKYNIRET-PSRHNKWVDDVQAELLQFTTKL-----ACADVAPE--A 210 Ostreococcus ... NP_611258 758 YTCVTSRVIDLS-------------SILAQMAKVKWDVNHV-IHQHSNYSDVLNRNIQSFAMCLee-iaKEVPVPSK--- 819 fruit fly XP_001317963 621 FPFFGPSMVNLT-------------EFDTQVKNTKWTINEP-PLDPHPFTKLWTENVSSFVKQVde-mkLAQDHKDE--I 683 Trichomonas v...
Q8RXC2 1006 QNLLLEYGVEIFAEML----VEGLSRIKRCTDEGRVLMSLDLQVLINGLQHFVPTKVKP-KLQIVETFIKAYY----LPE 1076 thale cress Q012F3 815 LAVLWGQAASLLEHVL----VDGFSRVKKCTDAGRALMSLDIQTLRAEFTKLAPSGTST-EWLFVTAYIDAFF----IPE 885 Ostreococcus ... Q7QF78 767 --VLWDSFVHVLTHLL----VEGFSNAKKCSAGGRALMQLDFTHFWSLLEIVSGGKHPE-HRAYVEQYVKAYY----LPK 835 Anopheles gam... Q16RR9 829 --ALWDCFVHVLTHLL----VEGFANAKKCSAGGRALMQLDFTHFISILEIISGGKYPD-HRAYVEQYIKAYY----LPK 897 yellow fever ... Q18602 826 EKFFWERAIYYSFKAL----VQGYGDGGKCSTEGRALMQLDFQMILMKLEPLCGIKPVP-HASFVDGYIKAYY----LPE 896 Caenorhabditi... Q4RKF9 196 SNVLWEHCIRLANRTL----VEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDLRPIP-DKEFVETYIKAYY----LTE 266 spotted green... Q54MU4 1008 NRPLRDHIVKLAFEYFiqqvVDGYSKIRKCTNEGRATMIQDVMSLKNGLEKISGGVRIP-NISFAEEYIKGFYqlaaFSE 1086 Dictyostelium... Q54NV0 1036 KNLLWENTITLAMETL----IDSYSRIKKCNYFGRNLMMMDVKKLQNNLEQLTTIRPIP-HIKHVENYITAFY----LPE 1106 Dictyostelium... XP_001634515 365 YGVLWDHCIRLANRTF----VEGFASAKKCSNEGRALMQLDFQQYLMKLEKLTDIRPIP-DREYVETYIKAFY----LTE 435 starlet sea a... XP_001419490 211 LDVLWQHAASVIQDSL----VDGFSKVKKCTDAGRALMALDVETLRGEFAKLAPSQSLAfDWRYVSTYINAFY----VPE 282 Ostreococcus ... NP_611258 820 --QVWNSMAHVATHLL----VEGFSNVKKCSAGGRALMQLDFANFMSFLELISNQKYPQ-HRSYVDVFIKTYY----FAP 888 fruit fly XP_001317963 684 LTSLWNYSSFSF--------INDLATIQKVTAEGRTAMLSDFRNMAHDYVNVTKKRIQP-DNSWVAGFVQAYF----LGI 750 Trichomonas v... Q012F3 815 LAVLWGQAASLLEHVL----VDGFSRVKKCTDAGRALMSLDIQTLRAEFTKLAPSGTST-EWLFVTAYIDAFF----IPE 885 Ostreococcus ... Q7QF78 767 --VLWDSFVHVLTHLL----VEGFSNAKKCSAGGRALMQLDFTHFWSLLEIVSGGKHPE-HRAYVEQYVKAYY----LPK 835 Anopheles gam... Q16RR9 829 --ALWDCFVHVLTHLL----VEGFANAKKCSAGGRALMQLDFTHFISILEIISGGKYPD-HRAYVEQYIKAYY----LPK 897 yellow fever ... Q18602 826 EKFFWERAIYYSFKAL----VQGYGDGGKCSTEGRALMQLDFQMILMKLEPLCGIKPVP-HASFVDGYIKAYY----LPE 896 Caenorhabditi... Q4RKF9 196 SNVLWEHCIRLANRTL----VEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDLRPIP-DKEFVETYIKAYY----LTE 266 spotted green... Q54MU4 1008 NRPLRDHIVKLAFEYFiqqvVDGYSKIRKCTNEGRATMIQDVMSLKNGLEKISGGVRIP-NISFAEEYIKGFYqlaaFSE 1086 Dictyostelium... Q54NV0 1036 KNLLWENTITLAMETL----IDSYSRIKKCNYFGRNLMMMDVKKLQNNLEQLTTIRPIP-HIKHVENYITAFY----LPE 1106 Dictyostelium... XP_001634515 365 YGVLWDHCIRLANRTF----VEGFASAKKCSNEGRALMQLDFQQYLMKLEKLTDIRPIP-DREYVETYIKAFY----LTE 435 starlet sea a... XP_001419490 211 LDVLWQHAASVIQDSL----VDGFSKVKKCTDAGRALMALDVETLRGEFAKLAPSQSLAfDWRYVSTYINAFY----VPE 282 Ostreococcus ... NP_611258 820 --QVWNSMAHVATHLL----VEGFSNVKKCSAGGRALMQLDFANFMSFLELISNQKYPQ-HRSYVDVFIKTYY----FAP 888 fruit fly XP_001317963 684 LTSLWNYSSFSF--------INDLATIQKVTAEGRTAMLSDFRNMAHDYVNVTKKRIQP-DNSWVAGFVQAYF----LGI 750 Trichomonas v...
Q8RXC2 1077 TEYVHWARAH----------------P---EYTKAQVVGLVNLVATM---KG------WKRKTrleVIEK 1118 thale cress Q012F3 886 HDFPKWLVIH----------------P---EYTKSQKLSLVHQASAGrrwSA------KLRAD---SIAA 927 Ostreococcus tauri Q7QF78 836 DLLEQWLLEP----------------R---GYSPKHLAGLVQCACSS---DK------KTRQRllaLVES 877 Anopheles gambiae str. ... Q16RR9 898 DLLEQWLVEGh--------------hR---GYSVKHLTGLVQCACSS---DK------KLRQRlltLVES 941 yellow fever mosquito Q18602 897 NGLEQWIKTHsvrgfsnlinyfpeilQ---EYSSKQLSSLLGAAAHV---SK------KARLRildALKD 954 Caenorhabditis elegans Q4RKF9 267 NDMEQFIKNH----------------R---EYSMKQLANLVNVCLGSh-iNK------KARQKllaAIDD 310 spotted green pufferfish Q54MU4 1087 KDVIEWAKQH----------------D---EYPIRYVVNLLNLIKAS-------------NPNlinQLEE 1124 Dictyostelium discoideu... Q54NV0 1107 SDLYNLARD-----------------S---EYTIKQVISIVN--VSNh-lKK------NEKQKlisDLEE 1147 Dictyostelium discoideu... XP_001634515 436 NEMERWIREH----------------K---EYSSKHLTSLVTCGVGSh-iTK------KGRQKllaIIEE 479 starlet sea anemone XP_001419490 283 KDVEKWMQIH----------------P---EFSKKQKLALVAHNASA---DRdrrwtaKFRQDllnAIET 330 Ostreococcus lucimarinu... NP_611258 889 EQFEQWIEQQ----------------RtgdEYSLKQLNNLIHCICVS---DK------RTRQRllqLLDA 933 fruit fly XP_001317963 751 EDFKKWAVENa---------------K---RYTQNHMMSIVETGFSDn-iKR------QDRKDlsnFVKS 795 Trichomonas vaginalis G3 Q012F3 886 HDFPKWLVIH----------------P---EYTKSQKLSLVHQASAGrrwSA------KLRAD---SIAA 927 Ostreococcus tauri Q7QF78 836 DLLEQWLLEP----------------R---GYSPKHLAGLVQCACSS---DK------KTRQRllaLVES 877 Anopheles gambiae str. ... Q16RR9 898 DLLEQWLVEGh--------------hR---GYSVKHLTGLVQCACSS---DK------KLRQRlltLVES 941 yellow fever mosquito Q18602 897 NGLEQWIKTHsvrgfsnlinyfpeilQ---EYSSKQLSSLLGAAAHV---SK------KARLRildALKD 954 Caenorhabditis elegans Q4RKF9 267 NDMEQFIKNH----------------R---EYSMKQLANLVNVCLGSh-iNK------KARQKllaAIDD 310 spotted green pufferfish Q54MU4 1087 KDVIEWAKQH----------------D---EYPIRYVVNLLNLIKAS-------------NPNlinQLEE 1124 Dictyostelium discoideu... Q54NV0 1107 SDLYNLARD-----------------S---EYTIKQVISIVN--VSNh-lKK------NEKQKlisDLEE 1147 Dictyostelium discoideu... XP_001634515 436 NEMERWIREH----------------K---EYSSKHLTSLVTCGVGSh-iTK------KGRQKllaIIEE 479 starlet sea anemone XP_001419490 283 KDVEKWMQIH----------------P---EFSKKQKLALVAHNASA---DRdrrwtaKFRQDllnAIET 330 Ostreococcus lucimarinu... NP_611258 889 EQFEQWIEQQ----------------RtgdEYSLKQLNNLIHCICVS---DK------RTRQRllqLLDA 933 fruit fly XP_001317963 751 EDFKKWAVENa---------------K---RYTQNHMMSIVETGFSDn-iKR------QDRKDlsnFVKS 795 Trichomonas vaginalis G3
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",