Conserved Protein Domain Family
Nucleoplasmin

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pfam03066: Nucleoplasmin (this model, PSSM-Id:145949 is obsolete and has been replaced by 427119)
Nucleoplasmin
Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.
Statistics
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PSSM-Id: 145949
Aligned: 23 rows
Threshold Bit Score: 137.069
Threshold Setting Gi: 74868011
Created: 28-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6PBF8    14 RPQNFLFGCELKADKREYSFKV-----E--DDENEHQLSLRTVSVGASAK-D-ELHVVEAEG---INYEGKT-IKITLAS 80  western clawed frog
Q27415     1 MAEESFYGVTLTAESDSVTWDVd----E--DYARGQKLVIKQILLGAEAK-EnEFNVVEVNT-----PKDS--VQIPIAV 66  fruit fly
Q9VAC4     1 MESESFYGVTLSEKEAIAQFEVpdvpeE--YIVHSHKLIIKQISLGPEAK-TgEFNVVQAETninDDGEKKT-LKIPIAV 76  fruit fly
Q7M6Z1    13 TAKNMLWGSELTQEKQTCTFRAq----G--ERKDSCKLLLSTICLGEKAK-E-EVNRVEILP-----QEDRK-SPITVAT 78  Norway rat
Q3UTE3    13 TAKNMLWGSELNQEKQTCTFRGq----G--EKKDSCKLLLSTICLGEKAK-E-EVNRVEVLS-----QEGRK-PPITIAT 78  house mouse
Q80W85    13 TAKNMLWGSELNQEKQTCTFRGq----G--EKKDSCKLLLSTICLGEKAK-E-EVNRVEVLS-----QEGRK-PPITIAT 78  house mouse
Q0P4A5    29 KPLSTLWGCELNESNKEESFKT-----D--DTNHQHQLALRTMCLGHTAK-D-EFNIVELVT---GEGNSNA-KAVPIAT 95  zebrafish
Q1HTZ9    13 KPVSLIWGCELNEQTKTFTFKVs----D--EDKSEHQLALRTVCLGNAAK-D-EFHIVEIVP---QAVEGSDaKPVPIAT 81  bullfrog
Q6GQG6    13 KPVSLIWGCELNEQNKTFEFKVe---dD--EEKCEHQLALRTVCLGDKAK-D-EFHIVEIVT---QE-EGAE-KSVPIAT 80  African clawed frog
ABN09649   1 MTDEFFYGVTLSSSHQSETWDPe----AkaEYPRSNKLVIRQALLGPDAKpD-ELNVIQVEA---MSLQEA--VKLPVAV 70  domestic silkworm
Q27415     1 MAEESFYGVTLTAESDSVTWDVd----E--DYARGQKLVIKQILLGAEAK-EnEFNVVEVNT-----PKDS--VQIPIAV 66  fruit fly
Q9VAC4     1 MESESFYGVTLSEKEAIAQFEVpdvpeE--YIVHSHKLIIKQISLGPEAK-TgEFNVVQAETninDDGEKKT-LKIPIAV 76  fruit fly
Q7M6Z1    13 TAKNMLWGSELTQEKQTCTFRAq----G--ERKDSCKLLLSTICLGEKAK-E-EVNRVEILP-----QEDRK-SPITVAT 78  Norway rat
Q3UTE3    13 TAKNMLWGSELNQEKQTCTFRGq----G--EKKDSCKLLLSTICLGEKAK-E-EVNRVEVLS-----QEGRK-PPITIAT 78  house mouse
Q80W85    13 TAKNMLWGSELNQEKQTCTFRGq----G--EKKDSCKLLLSTICLGEKAK-E-EVNRVEVLS-----QEGRK-PPITIAT 78  house mouse
Q0P4A5    29 KPLSTLWGCELNESNKEESFKT-----D--DTNHQHQLALRTMCLGHTAK-D-EFNIVELVT---GEGNSNA-KAVPIAT 95  zebrafish
Q1HTZ9    13 KPVSLIWGCELNEQTKTFTFKVs----D--EDKSEHQLALRTVCLGNAAK-D-EFHIVEIVP---QAVEGSDaKPVPIAT 81  bullfrog
Q6GQG6    13 KPVSLIWGCELNEQNKTFEFKVe---dD--EEKCEHQLALRTVCLGDKAK-D-EFHIVEIVT---QE-EGAE-KSVPIAT 80  African clawed frog
ABN09649   1 MTDEFFYGVTLSSSHQSETWDPe----AkaEYPRSNKLVIRQALLGPDAKpD-ELNVIQVEA---MSLQEA--VKLPVAV 70  domestic silkworm
Q6PBF8    81 LKPSVQPTVSLGGFEITPPVILRLKSGSGPVYVSGQHLVALEDLEStddedeehdvpspknakrtasdaaskvprkktrl 160 western clawed frog
Q27415    67 LKAGETRAVNPDVEFYESKVTFKLIKGSGPVYIHGHNI------------------------------------------ 104 fruit fly
Q9VAC4    77 LKVGETRSLRPNVEFPNGSVTFKLVQGSGPVHVCGKVEMNFGE------------------------------------- 119 fruit fly
Q7M6Z1    79 LKASVLPMVTVTGIELSPPVTFRLRAGSGPVFLSGQE-CYETSDMAwe-------------------------------- 125 Norway rat
Q3UTE3    79 LKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLE-CYETSDLTw--------------------------------- 124 house mouse
Q80W85    79 LKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLE-CYETSDLTw--------------------------------- 124 house mouse
Q0P4A5    96 LHAKSMPTVNLSGLDLHPPVTFRLKHGSGPVFVGAEH-VALEE------------------------------------- 137 zebrafish
Q1HTZ9    82 LKPSILPMATMVGIELTPPVTFQLKSGSGPIYISGQH-VALEADYSwae------------------------------- 129 bullfrog
Q6GQG6    81 LKPSILPMATMVGIELTPPVTFRLKAGSGPLYISGQH-VAMEEDYSwae------------------------------- 128 African clawed frog
ABN09649  71 LKVGESRHVRLDIEFPDAPVTFTLVQGSGPVHLIGHHLLGALLEEF---------------------------------- 116 domestic silkworm
Q27415    67 LKAGETRAVNPDVEFYESKVTFKLIKGSGPVYIHGHNI------------------------------------------ 104 fruit fly
Q9VAC4    77 LKVGETRSLRPNVEFPNGSVTFKLVQGSGPVHVCGKVEMNFGE------------------------------------- 119 fruit fly
Q7M6Z1    79 LKASVLPMVTVTGIELSPPVTFRLRAGSGPVFLSGQE-CYETSDMAwe-------------------------------- 125 Norway rat
Q3UTE3    79 LKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLE-CYETSDLTw--------------------------------- 124 house mouse
Q80W85    79 LKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLE-CYETSDLTw--------------------------------- 124 house mouse
Q0P4A5    96 LHAKSMPTVNLSGLDLHPPVTFRLKHGSGPVFVGAEH-VALEE------------------------------------- 137 zebrafish
Q1HTZ9    82 LKPSILPMATMVGIELTPPVTFQLKSGSGPIYISGQH-VALEADYSwae------------------------------- 129 bullfrog
Q6GQG6    81 LKPSILPMATMVGIELTPPVTFRLKAGSGPLYISGQH-VAMEEDYSwae------------------------------- 128 African clawed frog
ABN09649  71 LKVGESRHVRLDIEFPDAPVTFTLVQGSGPVHLIGHHLLGALLEEF---------------------------------- 116 domestic silkworm
Q6PBF8   161 eeedeaDSDEDDDDDDDDEEEDDEDEDEEDETPVKKTD 198 western clawed frog
Q27415   105 ------KDDVEVVDMEEDDEEDDVAEDEEDEHPKKRAK 136 fruit fly
Q9VAC4   120 ------FDDGQIYEEYSDEEEDSELEFDEEAAPQTNGK 151 fruit fly
Q7M6Z1   126 -----dDEEEEEEEEEDEDEDEDADLSLEE-IPIKQVK 157 Norway rat
Q3UTE3   125 -----eDDEEEEEEEEEEDEDEDADISLEE-IPVKQVK 156 house mouse
Q80W85   125 -----eDDEEEEEEEEEEDEDEDADISLEE-IPVKQVK 156 house mouse
Q0P4A5   138 ------YSDEEELDEEMDEEVEEEEEDIEE-SPVKKVT 168 zebrafish
Q1HTZ9   130 ----eeEGEEE-VEEEEEEEDPE--------SPPKPVK 154 bullfrog
Q6GQG6   129 ---eedEGEAEGEEEEEEEEDQE--------SPPKAVK 155 African clawed frog
ABN09649 117 ------EDMEEMEEEMLDEEEGDDSQFKEDENKRKGAg 148 domestic silkworm
Q27415   105 ------KDDVEVVDMEEDDEEDDVAEDEEDEHPKKRAK 136 fruit fly
Q9VAC4   120 ------FDDGQIYEEYSDEEEDSELEFDEEAAPQTNGK 151 fruit fly
Q7M6Z1   126 -----dDEEEEEEEEEDEDEDEDADLSLEE-IPIKQVK 157 Norway rat
Q3UTE3   125 -----eDDEEEEEEEEEEDEDEDADISLEE-IPVKQVK 156 house mouse
Q80W85   125 -----eDDEEEEEEEEEEDEDEDADISLEE-IPVKQVK 156 house mouse
Q0P4A5   138 ------YSDEEELDEEMDEEVEEEEEDIEE-SPVKKVT 168 zebrafish
Q1HTZ9   130 ----eeEGEEE-VEEEEEEEDPE--------SPPKPVK 154 bullfrog
Q6GQG6   129 ---eedEGEAEGEEEEEEEEDQE--------SPPKAVK 155 African clawed frog
ABN09649 117 ------EDMEEMEEEMLDEEEGDDSQFKEDENKRKGAg 148 domestic silkworm
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