Conserved Protein Domain Family
PA28_alpha

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pfam02251: PA28_alpha (this model, PSSM-Id:145415 is obsolete and has been replaced by 460507)
Proteasome activator pa28 alpha subunit
PA28 activator complex (also known as 11s regulator of 20S proteasome) is a ring shaped hexameric structure of alternating alpha and beta subunits. This family represents the alpha subunit. The activator complex binds to the 20S proteasome ana simulates peptidase activity in and ATP-independent manner.
Statistics
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PSSM-Id: 145415
Aligned: 18 rows
Threshold Bit Score: -1
Created: 21-Dec-2011
Updated: 16-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4SZX5          6 VSEESKK-QVDTF----CLTLTKEAEQLVSRFFPQKMEELQTL-LKT-SFSCKDVASLRAPLDIPIPDPV 68   spotted green pufferfish
Q1PBV6          6 MSPASKK-QVDGF----SQKITKEAEQLISSFFPEKIAEMDNI-LQG-SCSLKDLSVIRAPLDIPIPDPA 68   common carp
Q2EGS1          6 MSPASKK-EVDGF----TKKLTREAEQLVSTFFPQMIAEMDTL-LQA-SLALEDLSALRAPLDIPIPDPA 68   channel catfish
Q8AYH9          9 ISPEAAG-KVENV----QQHLHHEAEKLFSTVIPQKITQLDAL-LKDsALNL-DTSSLMAPLDIPIPDPP 71   Japanese flounder
Q7TP38          7 VDQEVKL-KVAAQlrppHPSFRTPSSRICS---PLPMSSLSPWgHQEpILNIHDLTQIHSDMNLPVPDPI 72   Norway rat
Q4RYJ6          7 VDSEIKT-KVDAF----RERITSEAEDLVANFFPNKLLELDNF-LKDpSINIRELKDIHSEINLTVPDPI 70   spotted green pufferfish
Q9V3P3          1 MPNDTVV-KVQEY----KDSLILKAELLITKGFPENIVRLNEL-LATpIFNERNFEEVHQDLNIPVLPPL 64   fruit fly
Q63798          9 LSGEARK-QVDAF----RQNLFQEAEDFLCTFLPRKIISLSQL-LQEdSLNVADLSSLRAPLDIPIPDPP 72   Norway rat
CAM19555       17 LSPSNYNfKVDSF----RERITSEAEDLVANFFPKKLLELDSF-LKEpILNIHDLTQIHSDMNLPVPDPI 81   house mouse
NP_001088027    7 VDQELKK-KVDCF----RERITSEAEDLVASFFPKKLLELDGF-LKEqILNVQDLTQIHSEMNLPVPDPI 70   African clawed frog
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