Conserved Protein Domain Family
Ig3_RPTP_IIa_LAR_like

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cd05739: Ig3_RPTP_IIa_LAR_like (this model, PSSM-Id:143216 is obsolete and has been replaced by 409401)
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
Ig3_RPTP_IIa_LAR_like: domain similar to the third immunoglobulin (Ig)-like domain found in the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR. LAR belongs to the RPTP type IIa subfamily. Members of this subfamily are cell adhesion molecule-like proteins involved in central nervous system (CNS) development. They have large extracellular portions, comprised of multiple Ig-like domains and two to nine fibronectin type III (FNIII) domains, and a cytoplasmic portion having two tandem phosphatase domains. Included in this group is Drosophila LAR (DLAR).
Statistics
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PSSM-Id: 143216
Aligned: 6 rows
Threshold Bit Score: 123.46
Threshold Setting Gi: 115670863
Created: 7-Aug-2007
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001077045  247 GGSVNLTCVAVGAPMPYVKWMTGevELTKDEEMPVGRNVLELTNirqSTNYTCVAISSLGMIEATAQVS 315  zebrafish
AAA28668      249 GSNLNLSCIAVGSPMPHVKWMKGseDLTPENEMPIGRNVLQLINiqeSANYTCIAASTLGQIDSVSVVK 317  fruit fly
ABN41557      164 GGSVNLTCVAVGAPMPYVKWMAGveELTKEDEMPVGRNVLELNNimqSADYTCVAISSLGMIEATAQIT 232  chicken
XP_785900     116 GGSVNLTCAAYGSPMPRVRWMKAgmDLDDMDDLPIGRNVLQLRDiyeSANYTCVATSLLGTIDTSARVT 184  purple urchin
NP_001081987  243 GGSVNLTCVAVGAPMPYVKWMAGleELTKEDEMPVGRNGLELTNikdSANYTCVAISSLGMIEAVAQIT 311  African clawed frog
P10586        246 GGSVNLTCVAVGAPMPYVKWMMGaeELTKEDEMPVGRNVLELSNvvrSANYTCVAISSLGMIEATAQVT 314  human
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