Conserved Protein Domain Family
RVT_thumb

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pfam06817: RVT_thumb (this model, PSSM-Id:115473 is obsolete and has been replaced by 311025)
Reverse transcriptase thumb domain
This domain is known as the thumb domain. It is composed of a four helix bundle.
Statistics
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PSSM-Id: 115473
View PSSM: pfam06817
Aligned: 41 rows
Threshold Bit Score: 76.5244
Threshold Setting Gi: 130648
Created: 29-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam06817 is not assigned to any domain superfamily.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75627267  421 RWEIEKIKLPEMDltKTTVNQIQKLVGVLNWAA-QL-YDGIRTKELCKLIRGVKPLEEIINWTEEALEEYGQNK 492
gi 75660804  374 QWKLQKVKIPEQD--KWTVNDIQKLVGALNWLS-QL-YPGIRTKEISKCTKGKKHLLEEVQLSAEAEEELQDNK 443
gi 75627077  423 NWKVQKMQLDMVK--NPTLNDVQKLMGNITWMS-SG-IPGLTVKHIAATTKGCLELNQKVIWTEEAQKELEENN 492
gi 82281629  418 KWTIQTKELIIPE--EPTLNELQKLVGIINWSS-QI-IPGLRIKALTNMMKGNQALDSKRRWTEEAKKEAEEAK 487
gi 82294457  300 KWTIQKTKLDIPE--VPTLNQLQKLAGVINWAT-QN-VGGIKIKALTELMKGNQQLDSYRQWTPEALGHLQKIK 369
gi 130597    393 TWTIQQKQLDIPE--QPTLNELQKLAGKINWAS-QA-IPDLSIKALTNMMRGNQNLNSTRQWTKEARLEVQKAK 462
gi 130649    360 KWRFQKHTLPEIKegTITLNKLQKLVGDLVWRQ--S-LIGKSIPNILKLMEGDRALQSERRIELRHVKEWEECR 430
gi 82303240  383 KWKYQKHKLPELQegVITLNKLQKIVGELVWRQ--S-LIGKSIPNIIKLMEGDRALQSERKIERIHVQEWEACQ 453
gi 82294408  770 RWRFQPRQIKIKK--VVTVNELQQMIGNCVWVQpEV-KIP--LSPLSDLLKGKTDLKDKIKLTEEAIQCLETVN 838
gi 52000846  249 KIKPQKIEIRKDT--LKTLNDFQKLLGDINWIRpTLgIPTYAMSNLFSILRGDSDLNSKRILTPEATKEIKLVE 320
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