Conserved Protein Domain Family
RRM1_hnRNPA3
?
cd12763: RRM1_hnRNPA3 
RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) and similar proteins
This subgroup corresponds to the RRM1 of hnRNP A3 which is a novel RNA trafficking response element-binding protein that interacts with the hnRNP A2 response element (A2RE) independently of hnRNP A2 and participates in the trafficking of A2RE-containing RNA. hnRNP A3 can shuttle between the nucleus and the cytoplasm. It contains two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), followed by a long glycine-rich region at the C-terminus.
Links
?
Statistics
?
PSSM-Id: 410156
Aligned: 6 rows
Threshold Bit Score: 158.292
Created: 20-Sep-2011
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
 
putative DNA
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Based on similarity to the sequence of Homo sapiens hnRNP A.
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 

Feature 1           # # ##                       # # #       ### #                         #  # #
P51991        33 QLRKLFIGGLS.[3].TDDSLREHFEKWGTLTDCVVMRD.[6].RGFGFVTYSCVEEVDAAMCA.[2].HKVDGRVVEPK 108 human
P51992        25 QLRKLFIGGLS.[3].TDDSLREHFEQWGKLTDCVVMRD.[6].RGFGFVTYSCVEEVDASMSA.[2].HKVDGRVVEPK 100 African clawed frog
P51968        25 QLRKLFIGGLS.[3].TDDSLREHFEQWGKLTDCVVMRD.[6].RGFGFVTYSCVEEVDASMSA.[2].HKVDGRVVEPK 100 African clawed frog
RLW01075       9 QLRKLFIGGLS.[3].TDDSLREHFEKWGTLTDCVVMRD.[6].RGFGFVTYSCVEEVDAAMSA.[2].HKVDGRVVEPK 84  Gouldian finch
XP_014349355  11 QLRKLFIGGLS.[3].TDESLREHFEQWGTLTDCVVMRD.[6].RGFGFVTYSCVSEVDAAMAA.[2].HKVDGRIVEPK 86  coelacanth
XP_007883080   6 QLRKLFIGGLS.[3].TDDSLRTHFEQWGRLTDCVVMRD.[6].RGFGFVTYSCVSEVDEAMSA.[2].HKVDGRVVEPK 81  elephant shark


Feature 1        #####
P51991       109 RAVSR 113 human
P51992       101 RAVSR 105 African clawed frog
P51968       101 RAVSR 105 African clawed frog
RLW01075      85 RAVSR 89  Gouldian finch
XP_014349355  87 RAVSR 91  coelacanth
XP_007883080  82 RAVSR 86  elephant shark

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap