2CRY


Conserved Protein Domain Family
IgI_5_KIRREL3-like
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cd05758: IgI_5_KIRREL3-like 
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Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains
The members here are composed of the fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2). This protein has five Ig-like domains, one transmembrane domain, and a cytoplasmic tail. Included in this group is mammalian Kirrel (also known as Neph1), Kirrel2 (also known as Neph3), and Drosophila RST (also known as irregular chiasm C-roughest) protein. These proteins contain multiple Ig domains, have properties of cell adhesion molecules, and are important in organ development.
Links
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Statistics
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PSSM-Id: 319310
Aligned: 4 rows
Threshold Bit Score: 169.635
Created: 31-Aug-2007
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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  next features
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:Ig strand A [structural motif]
Evidence:
  • None
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 

Feature 1         #####                                                                          
2CRY_A        13 GPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLE.[1].GTS.[1].RYTVETIST.[2].GVISTLTIS 81  human
NP_001079957 391 GPPIITSEAHYESILGEKARMECVIESTPTPDRIVWAWDKQSLE.[1].GSW.[1].RFSVETQVT.[2].GAVSFLVID 459 African clawed frog
ABQ57363     388 GPPIITAEATQQAIKHSKGKLECLVGSSPPPDKIVWTFGDMMLS.[1].GSS.[1].RFSVQTVNS.[2].GVLSSLILS 456 zebrafish
Q6UWL6       397 APPVVTALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLE.[1].GSQ.[1].RFLVETFPA.[9].GLISVLHIS 472 human


Feature 1                                     
2CRY_A        82 NIVRADFQTIYNCTAWNSFGSDTEIIRLK 110 human
NP_001079957 460 GTERSDFHTEFNCSAINQYGEDSVIVSLR 488 African clawed frog
ABQ57363     457 ETLAQDFQLRYNCTAWNRFGTGTALVTLE 485 zebrafish
Q6UWL6       473 GTQESDFSRSFNCSARNRLGEGGAQASLG 501 human

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