Conserved Protein Domain Family
RING-HC_XBAT35-like
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cd23129: RING-HC_XBAT35-like 
RING finger, HC subclass, found in Arabidopsis thaliana protein XB3 homolog 5 (XBAT35) and similar proteins
XBAT35, also known as ankyrin repeat domain and RING finger-containing protein XBAT35, or RING-type E3 ubiquitin transferase XBAT35, has no E3 ubiquitin-protein ligase activity observed when associated with the E2 enzyme UBC8 in vitro. It contains a typical C3HC4-type RING-HC finger.
Links
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Statistics
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PSSM-Id: 438491
Aligned: 18 rows
Threshold Bit Score: 86.9327
Created: 11-Jun-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Zn binding site
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C H C C C CClick to see conserved feature residue pattern help
Evidence:
  • Comment:based on the structures of other RING-HC fingers with bound zinc
  • Comment:C3HC4-type RING-HC finger consensus motif: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid and the number of X residues varies in different fingers
  • Comment:A RING finger typically binds two zinc atoms, with its Cys and/or His side chains in a unique "cross-brace" arrangement.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1            #  #           # #   #  #           #  #           
Q4FE47       407 NTGTCAICLDAPSEAVCVPCGHvAGCMSCLKEIksk-nwGCPVCRAKIDQVIKLY 460 thale cress
XP_024373877 418 KSGQCVVCWDAPAQVVCIPCGHlAGCMDCLSEIkek-gwGCPVCRTAIQQLIKVY 471 Physcomitrium patens
EFJ30981     420 AGGQCVVCWDAPAQGVCIPCGHlAGCMGCLQEIknk-kwGCPVCRSPIEQVVKVF 473 Selaginella moellendorffii
RLN73406     402 RESECIVCMENARDALCVPCGHaSCCYDCLRAItne-dpSCPVCRANVEGVVKIY 455 Nothophytophthora sp. Chile5
KUF78566     383 IRDRCIVCAENHRDSVCIPCGHvAGCYNCMRAVtqe-nsSCPVCRAHVDGVVRIQ 436 Phytophthora nicotianae
VFT86209     423 EVGTCVVCLDKPMEGVCVPCGHrAVCMTCAATLvahpsnKCPICRADIRQVIRMY 477 Aphanomyces stellatus
KUF83884     669 HTNECVICFDGPQEAVCVPCGHnAVCMDCAQELldt-trLCPVCRQQVREVIRLY 722 Phytophthora nicotianae
VFT94677     594 TREECIVCLDRPKQVVCVPCGHvAACVVCAEHIqqt-trKCPICRTDVRELIKLF 647 Aphanomyces stellatus
KXS10063     727 QAKECIVCFDQPKEAVLVPCGHiGMCMACAEQLkrq-gkRCPICRQNIERVIKAW 780 Gonapodya prolifera JEL478
KXS13956     519 GNEHCVVCFDRPKQAVLVPCGHiALCTLCATNLhyk-reKCPICRKYINQVVRTF 572 Gonapodya prolifera JEL478

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