7JTK


Conserved Protein Domain Family
DD_CrRSP_unchar

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cd22964: DD_CrRSP_unchar 
Click on image for an interactive view with Cn3D
dimerization/docking (D/D) domain of an uncharacterized subunit found in Chlamydomonas reinhardtii radial spoke 1
Flagellar radial spokes contribute to the regulation of dynein arm activity and thus the pattern of flagellar bending. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. This subfamily includes an uncharacterized protein found in Chlamydomonas reinhardtii radial spoke 1. It contains a conserved domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Statistics
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PSSM-Id: 438533
Aligned: 31 rows
Threshold Bit Score: 51.4606
Created: 27-Apr-2021
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
homodimeroligomer
Conserved site includes 17 residues -Click on image for an interactive view with Cn3D
Feature 1:homodimer interface [polypeptide binding site]
Evidence:
  • Structure:7JTK: Chlamydomonas reinhardtii uncharacterized protein forms a homodimer within radial spoke 1; contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1            ##  ##       #   #   ##  ### #   ##  #  ## 
7JTK_u         20 LYEKMRDYAHSNKvQELLQKMTADLFIERPADPVTWMIKWLSEEQK 65   Chlamydomonas reinhardtii
XP_029239815   11 EAPPEDVYLQQHGiPDLLRHLNHELVQQKPTNHLNFMLQWLANKAK 56   Trypanosoma rangeli
EPY16833      220 KEMEDEQYLKTFKiNTIISHLSLQLLQHKPEDHVEFARQWLLQSLE 265 
XP_028883078   18 LAAGDHDYLQQHGiTDIMTQLTRELNEQKPANHVAFMLQWLTNVAE 63   Trypanosoma theileri
RNC55948       10 IASPDDAYLQQRGiPGLWQQLSGELMEKKPANHLAFMLQWLSRLAG 55   Trypanosoma cruzi
XP_002785916   13 FESETEEYFKHNQiYETVRQLLQDVLLQRPTDPLHFMADWLNHGGN 58   Perkinsus marinus ATCC 50983
CUG68058       17 HTMLHQSYIDKHRlGDIVEHLSYALLVHKPSDHASFTRQWLANLSA 62  
CCW68823      298 VKNDIKEFFHESCvPQLFEKLSTDLLQNRPHNAVAYILSWLKEQRS 343  Phytomonas sp. isolate Hart1
CUG61972       97 VADQAVAYSARFKlPHLFDELLTALLAEAPEDVVRFSLTWIRWHKN 142 
CCC93567       60 KDMSLSEYLQHYEiPGILDRLTHSLLEEKPDVPVDFILSWLKRERA 105  Trypanosoma congolense IL3000

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