Conserved Protein Domain Family
TOS6
?
cd22955: TOS6 
GPI-anchored protein TOS6
TOS6 is a glycosylphosphatidyl inositol (GPI)-anchored protein. The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. The function of TOS6 is not known, but Saccharomyces cerevisiae Delta tos6 strains show significantly higher beta-glucosidase (BGL)-activity while maintaining wild type growth.
Links
?
Statistics
?
PSSM-Id: 438566
Aligned: 10 rows
Threshold Bit Score: 66.8623
Created: 21-Apr-2021
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q6CXL4         2 QFSTVISALTLSAVAvfaq------------------------------------------------------------e 21  Kluyveromyces l...
A7TLD4         2 KFSTVAATIASTFAVas--------------------------------------------------------------- 18  Vanderwaltozyma...
NP_014099      2 KFSTLSTVAAIAAFAsad-------------------------------------------------------------- 19  Saccharomyces c...
A6ZSH9         2 KFSTLSTVAAIAAFAsad-------------------------------------------------------------- 19  Saccharomyces c...
CDO91854       2 QFSTIVSIITLSAAAvlaq------------------------------------------------------------e 21  Kluyveromyces d...
BAP69583       2 QFSTLVAALFLSVSTaaaq------------------------------------------------------------s 21  Kluyveromyces m...
XP_018219597   2 RLSTAATIATVAAIAsad-------------------------------------------------------------- 19  Saccharomyces e...
SCV05138       2 QFSSAVFVSAAAAVVsasanqstvansttlvtvtscvdda-------------------casmttyttvdcnstlpgvst 62  Lachancea notho...
XP_001644773   2 KFSTVAATIASTFAVas--------------------------------------------------------------- 18  Vanderwaltozyma...
SCW04591       2 KFSSAVSLVSIAAVAvaenstyvnstetvvspsttlvtitsclddacaskttytthelstvtdtitscsggctptstate 81  Lachancea ferme...

Q6CXL4        22 tvvSDGVTYVDVTETPEVTVSAVSTELSTSTPYSTTTLAvat-----letYAGDNSTSTEHtVEPYSGAALKQe-VLGSS 95  Kluyveromyces l...
A7TLD4        19 -aaSESVTYVDITVTPEVTTSMVSTVKVTSTPYTTTTLSfavqsnsvshnETTSNSTQTTT-VSLFEGAGNTA--QVGAG 94  Vanderwaltozyma...
NP_014099     20 -stSDGVTYVDVTTTPQSTTSMVSTVKTTSTPYTTSTIAtls------tkSISSQANTTTHeISTYVGAAVKGs-VAGMG 91  Saccharomyces c...
A6ZSH9        20 -stSDGVTYVDVTTTPQSTTSMVSTVKTTSTPYTTSTIAtls------tkSISSQANTTTHeISTYVGAAVKGs-VAGMG 91  Saccharomyces c...
CDO91854      22 tvvSDGVTYVDITTTPEVTVSAVSTEVSTSTPLTTTTLSla--------tYSGDNATSTEHtLAPYSGAALRPe-VAGSS 92  Kluyveromyces d...
BAP69583      22 ttvSDGVTYVDVTTTPETTVSAVSTEVSTSTPFTTTTLStag-----ieqYTGDNSTSSTNsIAEYTGGAVKQg-VLGSL 95  Kluyveromyces m...
XP_018219597  20 -vtSDGVTYVDVTTTPQSTTSMVSTVKTTSTPYTTSTIAtls------tqPVSSQNNTTTPgISTFVGAAAKGs-VVGLG 91  Saccharomyces e...
SCV05138      63 taaADDITYVDLTTTPQSTTSMVKTVKSSSTPYLYTTLSt---------kNSTDAAGSSTQsLSVYSGAAENVvvGAGIG 133 Lachancea notho...
XP_001644773  19 -aaSESVTYVDITVTPEVTTSMVSTVKVTSTPYTTTTLSfavqsnsvshnETTSNSTQTTT-VSLFEGAGNTA--QVGAG 94  Vanderwaltozyma...
SCW04591      82 aagEDDITYVDVTTTPEVTTSVVSTVKSTSTPYSFTTVAts-------nlTSTYAYNSTTAaISTYEGSAPVV--AAGVG 152 Lachancea ferme...

Q6CXL4        96 LVGVVALVAAL 106 Kluyveromyces lactis NRRL Y-1140
A7TLD4        95 ALVAAVAAALL 105 Vanderwaltozyma polyspora DSM 70294
NP_014099     92 AIMGAAAFALL 102 Saccharomyces cerevisiae S288C
A6ZSH9        92 AIMGAAAFALL 102 Saccharomyces cerevisiae YJM789
CDO91854      93 LVGAFALVAAL 103 Kluyveromyces dobzhanskii CBS 2104
BAP69583      96 LMGAVALVAAL 106 Kluyveromyces marxianus
XP_018219597  92 AIVGAAAIALL 102 Saccharomyces eubayanus
SCV05138     134 ALVAGVAVALL 144 Lachancea nothofagi CBS 11611
XP_001644773  95 ALVAAVAAALL 105 Vanderwaltozyma polyspora DSM 70294
SCW04591     153 AVLGGLAVAIL 163 Lachancea fermentati
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap