This subfamily contains the NDUFA3-like subunit of plant NADH:Ubiquinone Oxidoreductase (Respiratory complex I), which is a redox-driven proton pump that plays an important role in creating the electrochemical gradient that powers mitochondrial adenosine triphosphate synthesis. NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) is a single-pass membrane protein and is considered an accessory subunit.
Comment:based on the interactions of human NDUFA3 subunit and Yarrowia lipolytica NI9M subunit with other subunits of the NADH:ubiquinone oxidoreductase complex