Conserved Protein Domain Family
Gal_Rha_Lectin_LAT1

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cd22839: Gal_Rha_Lectin_LAT1 
galactose/rhamnose binding lectin domain found in Caenorhabditis elegans latrophilin-like protein 1 (LAT1) and similar proteins
LAT1 plays a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. It is required for the alignment of the mitotic spindles and division planes. It may have a role in cell death events and play an essential role in normal defection and oocyte fertilization. LAT1 is involved in sperm function. it operates in pharyngeal pumping during feeding. LAT1 contains a galactose/rhamnose binding lectin domain at the N-terminus.
Statistics
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PSSM-Id: 438696
Aligned: 8 rows
Threshold Bit Score: 157.969
Created: 7-Jan-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
 
putative sugar
Feature 1:putative sugar binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #                                                                        
G5EDW2         38 TISHTICDGeAAELSCPaGKVISIVLGNYGRFSVAVCLPDNdiv--psNINCQNHk------------------------ 91   Caenorhabditi...
ABC86837       28 NSSIVVCEGgTAELVCPrGMVISIALANYGRYSARVCYDNEelddvvpMTQCHNPr------------------------ 83   Cooperia onco...
VDD86712       29 TSSEIFCEGdYANFSCPdGQYIALRIANYGRFSLGICNKDGva---dwSTTCQNDrtleilqktlgcileffsgkafarl 105  human pinworm
VIO93369       45 PIQKIFCEGeEANLECPiGRYIAIRLANYGRFTLGLCNPSHrt---dlSTTCQNDr------------------------ 97   Brugia malayi
VDK42153        9 SEQVIICEGkHANISCTeGRFIAIRLANYGRFTITQCNPTFnt---elSTTCQNDk------------------------ 61   herring worm
XP_024499042   15 DKEITICDGlNVTLQCDeAKIINFTMANYGRFAIEVCNDPNdfk-ipdEKICKNDk------------------------ 69   Strongyloides...
TMS35277       34 PNSVLICEGdVANFSCPvGTYISIHIANYGRYSLGPCNPSMni---dfNTVCQNAn------------------------ 86   Steinernema c...
TMS35278       34 PNSVLICEGdVANFSCPvGTYISIHIANYGRYSLGPCNPSMni---dfNTVCQNAn------------------------ 86   Steinernema c...
Feature 1                                   #     # ######        
G5EDW2         92 ------tKSILEKKCNGDSMCYFTVDKktftEDPCPNTPKYLEVKYNC 133  Caenorhabditis elegans
ABC86837       84 ------tMPTLRKSCDGRRECNFVVGNdffvHDPCPGVKKYLEVTYLC 125  Cooperia oncophora
VDD86712      106 gkkqyilNRLETFSCDGKRKCSFLVDErwfeRDPCPGVSKYLEASYSC 153  human pinworm
VIO93369       98 ------tLAIMKLSCDDKQRCLFVVETnrfgFDSCPGEPKYLEIVYSC 139  Brugia malayi
VDK42153       62 ------tLGILQLECNGKSECDFEVSNey-fGDACPKTSKYLDMQYDC 102  herring worm
XP_024499042   70 ------tLPILEKLCQGQSICSFNVNNkm-fEDTCIGLPRYLVARYNC 110  Strongyloides ratti
TMS35277       87 ------tIPRLQKRCNGQEWCVFPVSNdf-lGDPCPKTTKYLELQYTC 127  Steinernema carpocapsae
TMS35278       87 ------tIPRLQKRCGGSRQCSVPVSSgv-fDDFCPGTIKYLEATYSC 127  Steinernema carpocapsae

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