Conserved Protein Domain Family
Gal_Rha_Lectin_nemgal

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cd22838: Gal_Rha_Lectin_nemgal 
galactose/rhamnose binding lectin domain found in Hydra vulgaris nematogalectin and similar proteins
Nematogalectin, also called nemgal, is a nematocyst protein with an N-terminal GlyXY domain and a galactose/rhamnose binding lectin domain. There are two nematogalectins, A and B, in Hydra, and they are the products of alternative splicing. They are major components of the nematocyst tubule. Nematogalectin functions as a trimer that could bind to multiple chondroitin glycosaminoglycan molecules and stabilize the chondroitin proteoglycan layer.
Statistics
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PSSM-Id: 438695
Aligned: 21 rows
Threshold Bit Score: 115.834
Created: 7-Jan-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
 
putative sugar
Feature 1:putative sugar binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               #                                                                        
NP_001267836 163 PNFTVICEGEKGWLQCKq-YELIKVKNAFWGRDDQITCPKvpa--gldNARLCDTNPen-tIAKVNGQCKNEQACEVVAS 238 swiftwater hydra
NP_001267882 156 YNGTVKCEEDTAWLRCNe-YKHISIMSAFWGRRNFGLCTEhtg--nlvTNKYCPTTPl--fLTKVKDACEGTTMCEIRCT 230 swiftwater hydra
XP_012557016  35 SNTAIACQGDSENIMCDa-YQGIRIKDAFWGRDNKVDCQVdnplspltDTQMCFTLDkdyaYRKLAEVCQGQQTCQFEGT 113 swiftwater hydra
XP_012560620  35 DHAVAGCQEDNLYLQCQnrYNKLNISKVFYGRDDTTICTSrv----leSKKICNHTTpnsvIEKVILMCSGENRCKIPVT 110 swiftwater hydra
RMX48576     381 QKVAVACEGHKLKIKCPnkYDRIALYSTFYGRDDNNTCQHkv----lpSKGHCVKDEhr-iNEKLFDLCQGESKCSVAAT 455 Pocillopora dam...
RMX48576      42 VENTIVCEGQKAYVQCPspFDALAIVGTMYGRKNSKICVHps----ipSSVPCQEQEtq-vKAQIVGLCEGEHACEVAAN 116 Pocillopora dam...
RMX51057      37 NATALGCEGHMLTLSCAgqEEGLKINSAFWGRNDLKTCIPdkp---reQMKMCSPVEplyaVKKLRHVCEGQPTCGFPVS 113 Pocillopora dam...
XP_031557517  70 VRKVIACEDQKAYITCAniFNSIDIVSAMFGRKDPMVCLTpg----qdPASPCTEQEeq-iKQEVKDLCQGENKCEVSAS 144 Australian red ...
XP_031557549 170 QLAATACEGKKLRITCPnrSDRIIMYSTFYGRDDNNTCHHdv----lpSSGYCNEQQhr-vNEKVFDLCGHERKCIVAVN 244 Australian red ...
ABY71251      34 DHTIAACQEDNLMIQCRnrYNKITIKDVFYGRDNLFTCTSkt----fnATKLCDQPTptpiVQKVQMMCSGENKCKIPVT 109 Clytia hemispha...
Feature 1        #        # ######          
NP_001267836 239 NIFFD---DNSCGNVYKYLKIWYECIP 262 swiftwater hydra
NP_001267882 231 KFFFH---DQTCLDVYKYLEVYYKCIE 254 swiftwater hydra
XP_012557016 114 SLYFD---TELCPHIRKYARVKYECRQ 137 swiftwater hydra
XP_012560620 111 PEFLEmkdNMICPDIRKYLKVFYTCRQ 137 swiftwater hydra
RMX48576     456 SAFLGkknSIMCPEVYKYARVVYRCIQ 482 Pocillopora damicornis
RMX48576     117 NDFLAkagTTICPDVYKYLEIKYRCTP 143 Pocillopora damicornis
RMX51057     114 DAFFE---KPLCPGVSKFLKVVYDCRM 137 Pocillopora damicornis
XP_031557517 145 NDLLAmegTVICPNVMKYLEVKYRCMP 171 Australian red waratah sea anemone
XP_031557549 245 NHLFAkdnTTICPGVYKYLKVIYKCSQ 271 Australian red waratah sea anemone
ABY71251     110 SEFLEkksGEICPDIRKYLKVTYSCQQ 136 Clytia hemisphaerica

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