Conserved Protein Domain Family
Gal_Rha_Lectin_CSL1_rpt2

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cd22834: Gal_Rha_Lectin_CSL1_rpt2 
second galactose/rhamnose binding lectin domain found in Oncorhynchus keta CSL1 and similar proteins
The family includes a group of L-rhamnose-binding lectins, such as Oncorhynchus keta CSL1. CSL1 has hemagglutinating activity towards rabbit erythrocytes, but not human type B erythrocytes. Its hemagglutinating activity is inhibited by smooth-type lipopolysaccharide (LPS) from Klebsiella pneumoniae, Escherichia coli K-235, Shigella flexneri 1A, Aeromonas salmonicida and Salmonella minnesota and rough-type LPS from S. flexneri, but not by rough-type LPS from E. coli K12 and E. coli EH100. CSL1 agglutinates E. coli K12 and Bacillus subtilis. CSL1 contains two tandem galactose-binding lectin domains. This model corresponds to the second one.
Statistics
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PSSM-Id: 438691
Aligned: 8 rows
Threshold Bit Score: 114.477
Created: 29-Jan-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Conserved Features/SitesClick to see Conserved Features Help
 
putative sugar
Feature 1:putative sugar binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #                                                                       
P86177       187 PAKTSITCEg------STSSLDCGK---GVIKVFHANYGRRDgSTCSAGRHels--nqNCLQPktLDVVKQWCEGKSQCT 255 chum salmon
XP_028850037 143 SARTAVTCEf------GHMTLDCGQ---DIIEITSSNYGRRDgSTCSGDRPanqlamtECYLPrtLSDVSSSCNGKSLCS 213 denticle herring
XP_023693344  92 PAKTSITCQh------SSDILDCGT---DVIKVLHTNYGRRDtTTCSVGRPpkevmddNCFLSv-TAAISDRCNGKSKCS 161 Paramormyrops k...
KPP61064     153 YLEVFYGCFpaisgvyAFADVGCVFtgkDLIMVYDANYGRSNsTVCSAGRPdsqttttNCFLPgaFKVMSEKCNDRSKCE 232 Asian bonytongue
XP_018581478  22 EIKRSVMCEg------SPISLFCAH---SVIKIYDAKYRYTDsFFCGHVQPlpnmsnvTCSLPeaYKIISERCDGEALCD 92  Asian bonytongue
XP_023693344 187 ASRKSITCGg------PYGSISCEN---DLIRIYDAFYGQMSpTICSNGRPesqltntNCALAnvVDIVSKGCNDRTSCD 257 Paramormyrops k...
KTF82321     102 NSVFNDPCVgty--kyLQVSYECRPlkkGVISVHHANYGRRDlATCPHKLAtt----tHCYSSq-TARMRSRCNGKKTCH 174 common carp
KPP75373     548 DPSFSDPCVgty--kyLEVTYRCYParnNVIRILEANYGRRSrTICTTGRPqsqlenvNCLLPetFRVMSDRCDGKSRCE 625 Asian bonytongue
Feature 1            #    # ######        
P86177       256 LGLDPVf-gDPCFGTYKYLEVSYTC 279 chum salmon
XP_028850037 214 LSAGSFvpfDPCVGTYKYLEVTYIC 238 denticle herring
XP_023693344 162 VTPDDFs-tDPCYGSFKYLEVSYGC 185 Paramormyrops kingsleyae
KPP61064     233 VMASNSvftDPCYGTYKYLEVSYGC 257 Asian bonytongue
XP_018581478  93 LLSTSVf-pDSCKGTFKYLDIAYSC 116 Asian bonytongue
XP_023693344 258 LAFAFT---DPCFGTYKYLEVSYGC 279 Paramormyrops kingsleyae
KTF82321     175 VIASNKvffDPCKNVHKYLEVTYSC 199 common carp
KPP75373     626 MLAENSiftDPCYGTYKYLEVSYSC 650 Asian bonytongue

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