Conserved Protein Domain Family
Gal_Rha_Lectin_dCirl

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cd22830: Gal_Rha_Lectin_dCirl 
galactose/rhamnose binding lectin domain found in Drosophila melanogaster Latrophilin Cirl and similar proteins
Latrophilin Cirl (calcium-independent receptor for latrotoxin) is an adhesion-type G-protein-coupled receptor (aGPCR) that acts as a molecular sensor and signal transducer that detects and converts mechanical stimuli into a metabotropic response. It functions in mechanosensory neurons by modulating ionotropic receptor currents, the initiating step of cellular mechanosensation. The model corresponds to a galactose/rhamnose-binding lectin domain found at the N-terminus of Latrophilin Cirl.
Statistics
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PSSM-Id: 438687
Aligned: 26 rows
Threshold Bit Score: 147.77
Created: 4-Jan-2021
Updated: 17-Oct-2022
Structure
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Aligned Rows:
 
putative sugar
Feature 1:putative sugar binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1              #                                                                       #  
A1Z7G7          8 TAYACEGKKLTIECd-pGDVINLIRANYGRFSItICNDHGn-----vEWSVNCMFPkSLSVLNSRCAHKQSCGVLAATs- 80   fruit fly
XP_013388491   47 HAFACEGSVLHLDCsgdGGVIRVMRATYGRLSLaICNDRTvan--amDWNTICMSRrSRRKVRHLCQSKTFCTIPASNd- 123  Lingula anatina
TRY70743       38 TKYGCEGSSMVIKCd-eGTQINVVRANFGRFSGsICNEFGanaehasDWSVNCLEPrSLRVVNERCHRQAECEITVTSa- 115  Tigriopus cal...
XP_023334509   41 TGYTCEGDELLVNCd-pGNIIQIVRANYGRFSIaLCNEDGq-----tHWSVNCMAPnTRQILQKKCDSLNSCTVPVSSa- 113  Eurytemora af...
XP_023328919   40 TAYKCESERLELTCp-eDHKIKIIRANFGRFSIaICNRHGe-----mDMSVNCMAPsSTRVMKKRCDSRDSCSIQISSs- 112  Eurytemora af...
XP_023343374    2 SKYGCEGTQINLECe-dGSYISPVRANYGRFDAdICNPGLn-----kAWSTRCIQPtTLRQVNSLCQGKSSCSIDVTSs- 74   Eurytemora af...
XP_013416248   30 TAHACEGSYLDLKCsneTLVLHIIRANYGRLSNsVCNEEGk------AYSTDCLSPrAVRIVRQRCQGQFACSLPINNg- 102  Lingula anatina
XP_029639839   29 VAFVCEKNNLTLDCg-dNGIIRITRANYGRFTInQCNFFAqv----dGWNIQCHSKlSNIVARERCDGRVSCKIPAENsi 103  Octopus sinensis
XP_021378990   45 IAYACEGSTMYLSCk-qDELIRIVRANYGRFSLtICNQHGti----sGWKLQCVSMaSKRIVAERCDGRRLCNITVNNn- 118  Yesso scallop
XP_011446688   37 TSIACEKSVMKLDCerkNGIIRITRANYGRFTLtKCNSFGat----tGWNVSCLLPeSKRIVAERCDGYPKCEIMASNd- 111  Pacific oyster
Feature 1            # ######        
A1Z7G7         81 MFGDPCPGTHKYLEAHYQC 99   fruit fly
XP_013388491  124 VFGDACPGTPKYVQVEYRC 142  Lingula anatina
TRY70743      116 LFGDPCPGTYKYLEVHYTC 134  Tigriopus californicus
XP_023334509  114 LFDDPCPGTRKYLEIHYIC 132  Eurytemora affinis
XP_023328919  113 LFGDPCPNTPKYLEVHYGC 131  Eurytemora affinis
XP_023343374   75 VFGDPCPDTYKYLEIHYTC 93   Eurytemora affinis
XP_013416248  103 YFGDPCRKVYKYIEIQYRC 121  Lingula anatina
XP_029639839  104 FGGDPCSGTFKYLEVHYIC 122  Octopus sinensis
XP_021378990  119 VFGDPCVNTSKYLEAHYYC 137  Yesso scallop
XP_011446688  112 VFGDPCVNTFKYLQVYYTC 130  Pacific oyster

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