Conserved Protein Domain Family
FHA_KIF28P
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cd22709: FHA_KIF28P 
forkhead associated (FHA) domain found in kinesin-like protein KIF28P and similar proteins
KIF28P, also called kinesin-like protein 6 (KLP6), is a microtubule-dependent motor protein required for mitochondrion morphology and transport of mitochondria in neuronal cells. The FHA domain is a small phosphopeptide recognition module, but this group may lack the conserved residues that are required for binding phosphothreonine.
Links
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Statistics
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PSSM-Id: 438761
Aligned: 24 rows
Threshold Bit Score: 128.873
Created: 4-Sep-2020
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
B7ZC32        384 PHLLNLSEDPQLtRVLKYFIQagtqPAPCPRPALSPph-----pALRISDKHASFTNAd----------------GKVTV 442  human
XP_007886576  386 PYLLNVNEDPQLsGVVRHFIQn--gICTIGKTSVVKqdi--vlkGLGILDKHAVLTVSd----------------QKVGI 445  elephant shark
OCT79973      405 PYLLNINEDPQLsGVLKHFIQe--gASDVGQAPSNVit----vrGLGILPKHATFINTe----------------SKVFI 462  African clawe...
XP_025005039  444 PYLLNINEDPQLsWVLKHFIQd--gTCDVGQSTSNAii----lrGLGILDKHATFTNAd----------------GKVTI 501  chicken
XP_013410086  470 PYLRNVNEDPHLsGVVKYALQn--kEYVIGKPGNGVsie---lhGLGIQPHHAVMCNTg----------------QKVLI 528  Lingula anatina
XP_002732533  445 PFLQNVNEDLQLcGVIKYPLPe--gQTVIGRAGNTPqgnkiqlkGLGIQGSHVLVCNTg----------------TSVTL 506  Saccoglossus ...
XP_002677049  459 PSLVNLNEDPMMsGMLVYFFKi--gDTFLGRDKSNNiv----lnGLQIKPQHCIVSRTp----------------ENIII 516  Naegleria gru...
SPQ97763      468 PHLVNLHEDPMLsECVVYPFKa--gITKIGRPNAETkqdv-mlsGLNIKKEHAVVENVd----------------GKVTI 528  Plasmodiophor...
Q9NGQ2        459 PHLINLNEDPLMsESLIYYVKe--gKTRIGRSDSEIpqdi-ilnGLNIHKEHCIFENIn----------------GKVII 519  Dictyostelium...
XP_002900866  261 PHLLNLNEDQQMsEKLVYFINl--gVNRIGRIDADEeqni-vvgGLGILKEHCFIIRReqsqtidedleeekrelSALFI 337  Phytophthora ...

B7ZC32        443 TPHs----------------------------------------------kCKVAVNGVPITt--RTKLQHLDRLILGsN 474  human
XP_007886576  446 EPQs----------------------------------------------kARVIINGLLLLt--KYQLRHLDRVILGsS 477  elephant shark
OCT79973      463 KPHg----------------------------------------------kAKVVVNGVPIVl--NTKLQHLDRIILGsN 494  African clawe...
XP_025005039  502 APQd----------------------------------------------kCKVVVNGVTITa--ETELQHSDRVILGsN 533  chicken
XP_013410086  529 RPAvq---------------------------------------------qAKLLVNGVPLQk--ERTLTHLDRIMLGsS 561  Lingula anatina
XP_002732533  507 EPId----------------------------------------------vAKTIVNGLHVVq--QIELRHLDRIKLGsN 538  Saccoglossus ...
XP_002677049  517 IPIn----------------------------------------------sATVYVNGKLITk--DTELKCNDRIILGnN 548  Naegleria gru...
SPQ97763      529 RPVeg--------------------------------------------aqAKIFVNGDLVAagqSTELSPGDAVILGnN 564  Plasmodiophor...
Q9NGQ2        520 SPSnnfmnnnnnkensssttptsskspskpksekekennnddddgekkldrSYIYVNGVEINk--PTILTTGNRVILGnN 597  Dictyostelium...
XP_002900866  338 TACh----------------------------------------------gAKVFVNAEPLEeneERELHHCDRLVLGnS 371  Phytophthora ...

B7ZC32        475 STYLYVGF 482  human
XP_007886576  478 SFYLYVGF 485  elephant shark
OCT79973      495 SAYLYTGF 502  African clawed frog
XP_025005039  534 SAYLYVGP 541  chicken
XP_013410086  562 SLFLYVGF 569  Lingula anatina
XP_002732533  539 SIFLYIGF 546  Saccoglossus kowalevskii
XP_002677049  549 HVFRFTET 556  Naegleria gruberi strain NEG-M
SPQ97763      565 FVFRFMPP 572  Plasmodiophora brassicae
Q9NGQ2        598 HIFRFNNP 605  Dictyostelium discoideum
XP_002900866  372 NVFRVVIP 379  Phytophthora infestans T30-4
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