5A8I


Conserved Protein Domain Family
FHA_ArnA-like
?
cd22680: FHA_ArnA-like 
Click on image for an interactive view with Cn3D
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing protein ArnA and similar proteins
ArnA is an FHA domain-containing protein from Sulfolobus acidocaldarius that was shown to strongly interact with ArnB, a von Willebrand domain-containing protein. They act synergistically and negatively to modulate motility. ArnA is involved in regulating archaella expression in S. acidocaldarius. The FHA domain is a small phosphopeptide recognition module.
Links
?
Statistics
?
PSSM-Id: 438732
Aligned: 11 rows
Threshold Bit Score: 99.7222
Created: 8-Sep-2020
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
putative
Conserved site includes 12 residues -Click on image for an interactive view with Cn3D
Feature 1:putative phosphopeptide binding site [polypeptide binding site]
Evidence:
  • Comment:GR at the C terminus of strand beta3, SRxH just preceding beta5, and motif SxNG in the beta6-beta7 turn indicate a canonical mode of pThr recognition.
  • Comment:also based on structures of other FHA domains with bound phosphopeptide
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                       ###           #           #### #                 
5A8I_A       101 YYIYFIQtpnenlvnKKVLLNFdl-fpSVSMGRSpe---nIVIVPDS----------EVSRKHAVIYLDn--SELYIEDL 164 Sulfolobus acid...
EQB71440      74 LEFQFVQspmdslmgKKVKVNFsv-fpSVSVGRSpe---nVMQIPDA----------SVSRMHAKITLDg--GSYYIEDV 137 Thermoplasmatal...
OWJ54435     108 YYLVVINspvtelmgMKIPLQFev-ygRISLGRSle---nVIVVPDP----------SVSRRHALVYIEd--DKVVLEDL 171 Pyrodictium del...
KUO88315      26 LELTFVEsprdfmkdFKVVFDLsi-irEITLGRSpe---nVVVIPDP----------TVSRKHAVITVVg--NELLIKDL 89  Vulcanisaeta sp...
WP_009989723 104 YYLLFINtpnpafnkTKLPLDFdi-fpSISIGRSpe---nVIVIPDP----------EVSRKHAIISFEn--NELYLEDL 167 Saccharolobus s...
WP_011007522  46 VVVEILEspieslvgKKFEFKVttpgvIVTIGRAve---nHVVVTDP----------AVSRRHLRLIVTs--NGIVVEDV 110 Pyrobaculum aer...
WP_011576716   3 IVLELLSrkd--qtlKYFKFNKs----EILVGRDhh---cDLRLEDP----------YISAEHVRITQDsqdQSIFFEDC 63  Pseudoalteromon...
WP_071388327 129 MTIEYKEke----teKSFPFTSs----IVNVGRDpev-cdLVLSEDP----------FIGRNHAMILNKe--NKFFVVDL 187 Anaerobacillus ...
RLI56806     544 LVLEIKG--------KKFEIDGi----EVVIGRNlitrriEIRSPTSgtidtgikepFISANHLKVYVKs--NEIYVEDL 609 Candidatus Thor...
OQY32310      36 GVITTLSsdk---lgKSYIIDRe----SVLIGRDps---cDICIDDP----------LISKVHSRFTVEe-dKIFRIEDL 94  Spirochaetaceae...
RMG12605       2 PSLEILSgkh---agQVFSFAG-----DAKIGKDds---cTIQLTDP----------GVSRFHAQVRVSg--GTVQIEDL 58  Planctomycetes ...

Feature 1         # ##                                        
5A8I_A       165 nSTNGTYVYdg--kqFTPIkg--kQKIEpNSIIKLGNq-TIVRIL 204 Sulfolobus acidocaldarius
EQB71440     138 gSSNGTFIYdg--skFVEVke--kTKIQeKSLVKFGEd-TIVKVT 177 Thermoplasmatales archaeon A-plasma
OWJ54435     172 gSTNGTYIYdpgeavFRRVd---rAVLKpGMLVRLGEa-TVLRVE 212 Pyrodictium delaneyi
KUO88315      90 nSTNGTYVLdg--neFKRIs---eYRFSnETVIRLGYy-TVIRLS 128 Vulcanisaeta sp. MG_3
WP_009989723 168 nSTNGTYVYdg--kvFQPVkg--kIKVQhNSIIKLGNn-TVVRIV 207 Saccharolobus solfataricus
WP_011007522 111 gSSNGTFLLee--gkERQIk---vENIGkKGLIRIGN--TKLRVS 148 Pyrobaculum aerophilum
WP_011576716  64 qTINGTLVN------KQSMt---sGKLHgNDILKLGR--TRLKVV 97  Pseudoalteromonas atlantica
WP_071388327 188 eSKNGTFID------GERItg--qKPIEaNQPFTIGRteMVIKVI 224 Anaerobacillus alkalidiazotrophicus
RLI56806     610 dSTNKTFIG------DKELeprkpMKVAqNQIINLAKk-VNLKIT 647 Candidatus Thorarchaeota archaeon
OQY32310      95 gSTNGTFLN------KKKLsk--pSQLHySDRIVLGG--TIFRFF 129 Spirochaetaceae bacterium 4572_59
RMG12605      59 gSSNGTYVNf-----KKRAkg-dpATLNdKDIVFFGR--TVSKFW 95  Planctomycetes bacterium

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap