Conserved Protein Domain Family
KH-I_RIK_like_rpt2
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cd22472: KH-I_RIK_like_rpt2 
second type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana protein RIK and similar proteins
RIK, also called rough sheath 2-interacting KH domain protein, or RS2-interacting KH domain protein, is a RNA binding protein that acts together with RS2/AS1 in the recruitment of HIRA. RIK contains two type I K homology (KH) RNA-binding domains. The model corresponds to the second one.
Links
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Statistics
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PSSM-Id: 411900
Aligned: 7 rows
Threshold Bit Score: 142.583
Created: 20-Jul-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putativeGXXG motif
Feature 1:putative nucleic acid binding site [nucleic acid binding site]
Evidence:
  • Comment:flanked by the GXXG motif and a variable ssRNA/DNA binding loop
  • Comment:Based on the structure evidence that other KH-I superfamily members bind RNA/ssDNA.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                            # ### #####  ##  ##    ####                                  
Q9LIA4        191 KMLSTCVYLGFEad--psSNVAARIRGPNDQYINHIMNETGATVVLRGRGSGSlenqhgdEAQLPLHLLLSGsnpKSIDD 268  thale cress
KAA6418530    271 LTQTVALYVGVDap--phFNLHQRLRGPGDSYLQHISSTTGATVTLRGRGSGGm-----yESPDHLHLFVSAtnsKGFEE 343  Trebouxia sp....
PNW78613      261 PPPACVIYTGVTqp--ggFPLADKIKGPGNTYVQHIATTTGATVQLRGRGSIDa------EGPDPMHVFISAaapKALED 332  Chlamydomonas...
GBG00503      233 NPHQAQVYVGFDap--paFELVAKIRGRANSYLGHIATSTGTAVRLVGRGAGGa-----dEAAEPLHVDVSGsdpARVAE 305  Raphidocelis ...
EFN52534      301 GPGWLCLYPRCEgaa-peFDAAGRLRGPNGSYLQHIQSATGVAASVAGRGSGVq-----pEGPFPLHLHLASqdaAKLEE 374  Chlorella var...
XP_011400882  112 GPGFHCLYLGIPascpasWDLAGRVRGPNNAYLGHIASACACVAALRGAGSATv-----pETREPLHVFLAAgdgAALEK 186  Auxenochlorel...
XP_024370702  210 PAFTAVINVGIEad--psFNLIGRIRGPNDQYIKHIMSQAGALVAIRGKGSGYldh-tgaESQQPLHLFISSdnsKALDD 286  Physcomitrell...

Feature 1                                
Q9LIA4        269 AKRLAENLMDTISVEFGASRVSS 291  thale cress
KAA6418530    344 AKGLCVNLIDTVRAEHSKMFPPQ 366  Trebouxia sp. A1-2
PNW78613      333 AKSLVLDLLRTVGDEFKRSYPAA 355  Chlamydomonas reinhardtii
GBG00503      306 ARALAQDLVATVRKTFEAAYPRG 328  Raphidocelis subcapitata
EFN52534      375 GRRLAANLIDTVREDFKAAYPSA 397  Chlorella variabilis
XP_011400882  187 ARGLTTSLIDTVRADFVTAFPGL 209  Auxenochlorella protothecoides
XP_024370702  287 ARKLSENLLDTIRGDSSSFRAAT 309  Physcomitrella patens

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