Conserved Protein Domain Family
KH-I_RCF3_like_rpt5

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cd22463: KH-I_RCF3_like_rpt5 
fifth type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein RCF3 and similar protein
RCF3, also called protein ENHANCED STRESS RESPONSE 1 (ESR1), or protein HIGH OSMOTIC STRESS GENE EXPRESSION 5 (HOS5), or protein REGULATOR OF CBF GENE EXPRESSION 3, or protein SHINY 1 (SHI1), acts as negative regulator of osmotic stress-induced gene expression. It is involved in the regulation of thermotolerance responses under heat stress. It functions as an upstream regulator of heat stress transcription factor (HSF) genes. HEN4, also called protein HUA ENHANCER 4, plays a role in floral reproductive organ identity in the third whorl and floral determinacy specification by specifically promoting the processing of AGAMOUS (AG) pre-mRNA. It functions in association with HUA1 and HUA2. RCF3 contains five K-homology (KH) RNA-binding domains. The model corresponds to the KH5 domain of RCF3.
Statistics
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PSSM-Id: 411891
Aligned: 5 rows
Threshold Bit Score: 99.428
Created: 21-Aug-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putativeGXXG motif
Feature 1:putative nucleic acid binding site [nucleic acid binding site]
Evidence:
  • Comment:flanked by the GXXG motif and a variable ssRNA/DNA binding loop
  • Comment:Based on the structure evidence that other KH-I superfamily members bind RNA/ssDNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                   # ### #####  ##  ##    ####                                   
Q8W4B1        576 RSTLEVVLPeAVVPKLVTKSRNKLAQISEWSGASVTIVEDrp---eETQNIIRISGTpEQAERAQSLLQGFI 644  thale cress
XP_005827476  558 LIRIEMQIPvTAAGMIVGKQGKTIKNIHHRTGATVALVQDvnp-edETKKVLAIQGKkSQVKLARDLVIDLM 628  Guillardia theta CCMP...
EDQ88068      269 PPMLQFSIPeAIVGRIIGKSGRTIRHIQDVSGAFARVVNQaypalePAQRILQLSGTnSQLKRALQMCVRYF 340  Monosiga brevicollis MX1
A0C5G6        340 AKKIEFQVHdQFVALIIGKKGVTIKAISERSGAFVAITQSpdyqvrPDHKAFVLSGTeEQLNIAIREIETLL 411  Paramecium tetraurelia
VVW90098       77 SHKIELEIPvRLIGLIIGKGGETIKGINAKTGAFVCLSKDey--skRNRKIVTITGTeDLCLIAKYEVEKII 146  Nymphaea colorata

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