Conserved Protein Domain Family
KH-I_HEN4_like_rpt5
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cd22462: KH-I_HEN4_like_rpt5 
fifth type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana KH domain-containing protein HEN4 and similar protein
HEN4, also called protein HUA ENHANCER 4, plays a role in floral reproductive organ identity in the third whorl and floral determinacy specification by specifically promoting the processing of AGAMOUS (AG) pre-mRNA. It functions in association with HUA1 and HUA2. HEN4 contains five K-homology (KH) RNA-binding domains. The model corresponds to the KH5 domain of HEN4.
Links
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Statistics
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PSSM-Id: 411890
Aligned: 11 rows
Threshold Bit Score: 83.4528
Created: 21-Aug-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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putativeGXXG motif
Feature 1:putative nucleic acid binding site [nucleic acid binding site]
Evidence:
  • Comment:flanked by the GXXG motif and a variable ssRNA/DNA binding loop
  • Comment:Based on the structure evidence that other KH-I superfamily members bind RNA/ssDNA.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                # ### #####  ##  ##    ####                                       
F4KDN0        778 VEIRVPaNAMSFVYGEQGYNLEQLRQiSGARVIIHeppl-------gtsdRIIVISGTPDQTQAAQNLLHAFI 843  thale cress
P58223        538 LEILIPaHAMSKVMGKGGGNLENIRRiSGAMIEISaskt-------shgdHIALLSGTLEQMRCAENLVQAFV 603  thale cress
4314357       583 LELAVEkDALGSLYGRDGTGVDNLQQiSGANVDVKdpt---------gteATVLISGNPEQARTAMSLIESIL 646  thale cress
EFJ09837      563 IDVLIPeVTFSAVLGQNGDNLTQISKmSGAKVTLAdgct-------atgdRLIEISGTPDQTNIAKTVVEAFA 628  Selaginella moellend...
NP_001183239  571 YETAVSgSILTLVYGDNGSNLAKLTEvSGADIIVYnpps-------egneAMIVVSGPPDQAQSAQRLLVELI 636  Zea mays
XP_024527964  584 IEITIPgTVIGSIIGKGGSNIAQIRQiSGAKVKLHdpkp-------gsdkRIIEISGAPDQAQAAQSLLEAFM 649  Selaginella moellend...
Q21920       1810 WKLTIPaYAASRVIGKGGSNVNAVREaTGAIIEINkiqes-----nkqaeRTVLAKGTPEMVRYAMNIINYMI 1877 Caenorhabditis elegans
EEC67461      550 TFIEIPiQQVGCFVGEKGGNIMKLENiSGAKIHRLgvds-------ythmQLYKISGTPHQISKAENLVKEFL 615  Indian rice
EGD76199      277 IQMMIPgEMVGHLIGRAGASIKYITEtSGAGIELLplqypa----nmspvRIVKIEGTPRQLTHAFALMLRKF 345  Salpingoeca sp. ATCC...
XP_013760306   81 ARLLIPaHSVGSVIGRGGACINLIREtSGARVSVLkadrssrrygpapefTVVRLEGSIQCVSHAQQIITHLI 153  Thecamonas trahens A...
XP_028408758  376 IHIAVPkNAVGAIIGREGSVVNGIRHaSGASVQVLksde-------daveTLVELRGYPHQLTMAEGAIFQKI 441  Dendronephthya gigantea

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