Conserved Protein Domain Family
KH-I_ScSCP160_rpt7

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cd22452: KH-I_ScSCP160_rpt7 
seventh type I K homology (KH) RNA-binding domain found in Saccharomyces cerevisiae Protein SCP160 and similar proteins
SCP160, also called protein HX, is a new yeast protein associated with the nuclear membrane and the endoplasmic reticulum. It is involved in the control of mitotic chromosome transmission. It is required during cell division for faithful partitioning of the ER-nuclear envelope membranes which enclose the duplicated chromosomes in yeast. SCP160 contains seven K-homology (KH) RNA-binding domains. The model corresponds to the seventh one.
Statistics
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PSSM-Id: 411880
Aligned: 8 rows
Threshold Bit Score: 86.2205
Created: 19-Aug-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putativeGXXG motif
Feature 1:putative nucleic acid binding site [nucleic acid binding site]
Evidence:
  • Comment:flanked by the GXXG motif and a variable ssRNA/DNA binding loop
  • Comment:Based on the structure evidence that other KH-I superfamily members bind RNA/ssDNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                    # ### #####  ##  ##    ####                             
1173344      1152 TYAGYVWGAdtRRFNMIVGPGGSNIKKIREAADVIINVPRksdkvNDVVYIRGtKAGVEKAGEMVLK 1218 Saccharomyces cerevisiae S...
OBA25973     1231 PFFGFIDLKspKAVAKVLGPNGSNINKIRFQSGCVIDVPKrn-seKKILTVFGpKSNVEKALELIKK 1296 Hanseniaspora valbyensis N...
OEJ84346     1208 QFYGFVYASnpSKFSRVLGYGGIDINLTRKRTGCIIEVPKktexvNDVIVIKGtKEGVEQSIELIKK 1274 Hanseniaspora osmophila
XP_018227377 1172 TATGYLKVPp-NYYGIIIGQGGSRISQIKNESDCCINIPRtn--nGNLITLRGtLDGLEKARAMIID 1235 Pneumocystis carinii B80
EDK41730     1121 DSRGWIFASnpGSFSKVVGPQGARISQLRKKFNVFVIVPRkgdkhEQFIYLVGkQDAIEAASKEIVK 1187 Pichia guilliermondii ATCC...
XP_018986251 1102 DHDAWFKTRp-SVMNRIVGARGETVNGIREKSLCFIVVPKatdadADVVYLRGtVEGLKVAEKELKA 1167 Babjeviella inositovora NR...
ORX70730     1258 GVEAAVRVEp-RLHRRIIGKQGSNIAKIRDATGCEVTVPKrg-deSVWVTVTGeRAGVERAIEMIQE 1322 Linderina pennispora
XP_030535123  384 IIRKDISVEp-RIHGYIIGRAGAKVDQIREESGAFIFVPKnd-eqSEFITLEGtLEAVTRAEEKINA 448  Rhodamnia argentea

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