Conserved Protein Domain Family
KH-I_ScSCP160_rpt6

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cd22451: KH-I_ScSCP160_rpt6 
sixth type I K homology (KH) RNA-binding domain found in Saccharomyces cerevisiae Protein SCP160 and similar proteins
SCP160, also called protein HX, is a new yeast protein associated with the nuclear membrane and the endoplasmic reticulum. It is involved in the control of mitotic chromosome transmission. It is required during cell division for faithful partitioning of the ER-nuclear envelope membranes which enclose the duplicated chromosomes in yeast. SCP160 contains seven K-homology (KH) RNA-binding domains. The model corresponds to the sixth one.
Statistics
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PSSM-Id: 411879
Aligned: 6 rows
Threshold Bit Score: 98.2958
Created: 19-Aug-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
 
putativeGXXG motif
Feature 1:putative nucleic acid binding site [nucleic acid binding site]
Evidence:
  • Comment:flanked by the GXXG motif and a variable ssRNA/DNA binding loop
  • Comment:Based on the structure evidence that other KH-I superfamily members bind RNA/ssDNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               # ### #####  ##  ##    ####                                  
1173344    940 VTKTIDIPAERKGALIGPGGIVRRQLESEFNINLFVPnkd-dpSGKITITGAPENVEKAEKKILNEIIRE 1008 Saccharomyces cerevisiae S...
NP_496136  136 ASREIDIPKDHHGRLIGKEGALLRNLEAETNCRIQIPnrd-gpSSKITITGPREGIQRAAAHILAVSERE 204  Caenorhabditis elegans
CBY11624   143 GSIDVLIPKEHHRFILGKGAETLKKIEAETGTRIQVPkadeaeGAPIRITGAKDAMKACKAKIERISAEQ 212  Oikopleura dioica
EDQ87291   262 ASIDVSIPKEYHRYIIGTKGAVRKEIEDKHACRISIPktd-dpSPVIKVVGTTEGCRAAAAAIQKIADEK 330  Monosiga brevicollis MX1
PAV74677    71 HVQELDVPKGLQLKITGKENELIRELERECGCRIAIPgkd-dsSLTWRISGTQDGVEQATARILSSIEQE 139  Diploscapter pachys
RZF46152    18 AQDSIDVPKEYHRLILGKQAARLKELEKESGASIKVPaaa-daSTRIQVTGPRDAIRRATALIKQISDEQ 86   small brown planthopper

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