4QMF,5JPQ


Conserved Protein Domain Family
KH-I_KRR1_rpt2

?
cd22394: KH-I_KRR1_rpt2 
second type I K homology (KH) RNA-binding domain found in KRR1 small subunit processome component and similar proteins
KRR1, also called HIV-1 Rev-binding protein 2, or KRR-R motif-containing protein 1, or Rev-interacting protein 1, or Rip-1, or ribosomal RNA assembly protein KRR1, is a nucleolar protein required for 40S ribosome biogenesis. It is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. KRR1 contains two K-homology (KH) RNA-binding domains. The model corresponds to the second one.
Statistics
?
PSSM-Id: 411822
Aligned: 54 rows
Threshold Bit Score: 123.447
Created: 20-Jul-2020
Updated: 25-Oct-2021
Structure
?
Program:
Drawing:
Aligned Rows:
 
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                ##  ##                                  #                          #    
4QMF_B        90 MACDVIKIGNfvTNKERFVKRRQRLVGPNGNTLKALELLTkCYILVQGNTVSAMGPFKGLKEVRRVVEDCMk-NIHPIYH 168 Saccharomyces c...
5JPQ_g       119 MACDIIKIRSmvRNKERFVKRRQRLLGQNGTTLKALELLTqTYILVHGNTVSVMGGYKGLKEVRRVVEDTMn-NIHPIYL 197 Chaetomium ther...
NP_584734    102 YFCEVIDIKKmvSSDKVFEKRRDRLVGPKEMTLKAIQILTrCYVLVHGKTVSIIGGFRGVEEAKKIVVDCMn-NIHPMYQ 180 Encephalitozoon...
XP_654627    108 YWCDIIKIGNmiKNKERFVKRRQRLVGPNGATQKAIEILTgCFILIQGKTVSVIGSPSGIKMVRKIVEDCMd-NIHPIYN 186 Entamoeba histo...
XP_001713208 110 IFCEIIKISKftSSRQSFLKKRKRLIGNNGVTVKTIELLTkCYILIQGNTVACMGKFRDLKWCINIITKSMt-NNHPIFY 188 Guillardia theta
EET00901     136 VDCDIIRIKNmtPRKDSFIKRRARFVGPNAQTLKAIELLTdTKIQVQGNTVAVMGASRGVGLVRNIVTDCIerNIHPVQH 215 Giardia intesti...
EFC50278     104 VFSEVMKIGNlcRNKEVFTKRRQRLFGPDGSTLKALQLLTgCFIFIQGKTVSVIGEVNGIKLVSEVITDCMn-NIHPIYH 182 Naegleria gruberi
EPY31604     111 IFSDIINIAMkgVSTQRFVKRRDRLIGPKAQTLKAIEILTgCYVLVQGKTVAVMGPAKGIQLVRKVVEDCMn-NIHPIYN 189 Strigomonas cul...
KNH05011      94 YTYEIMNIGNavNNTMRFVKRRERLLGPQGQTLRTLEILSdCYILVQGKTVSIIGPEAGLKKAKKIIVDCMr-NIHPLYG 172 Perkinsela sp. ...
SBT70607     134 TFCDIIKINGyiRNKNKFIKRRQRLLGSNGTTLKALEILTnCYICVHGKTVSLIGYFKSLKIVRRIVIDCMk-NIHPVYH 212 Plasmodium mala...
Feature 1                      
4QMF_B       169 IKELMIKRELAKRP 182 Saccharomyces cerevisiae S288C
5JPQ_g       198 IKELMIKRELAKDP 211 Chaetomium thermophilum
NP_584734    181 IKRLVEKRKMESDE 194 Encephalitozoon cuniculi GB-M1
XP_654627    187 IKALMIKKELMKNE 200 Entamoeba histolytica HM-1:IMSS
XP_001713208 189 LKNIQIKKKLMNDE 202 Guillardia theta
EET00901     216 IKTLMIKRELAKIP 229 Giardia intestinalis ATCC 50581
EFC50278     183 IKQLMVKKELKNSS 196 Naegleria gruberi
EPY31604     190 LKQLLIKRELAKRE 203 Strigomonas culicis
KNH05011     173 LKRLMILKELEANP 186 Perkinsela sp. CCAP 1560/4
SBT70607     213 IKELIAKRELEKNN 226 Plasmodium malariae

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap