6BRO,5HYW


Conserved Protein Domain Family
F-box_D3-like
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cd22140: F-box_D3-like 
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F-box domain found in Oryza sativa F-box/LRR-repeat Max2 homolog (D3) and similar proteins
D3 is the ortholog of Arabidopsis MORE AXILLARY GROWTH2 (MAX2) and DWARF14 (AtD14) in rice. These proteins are essential signaling components to regulate strigolactone (SL)-repressed plant branching. In rice shoot branching inhibition, the SL-metabolizing alpha/beta hydrolase D14 interacts with the F-box protein D3 to ubiquitinate and degrade the transcription repressor D53. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.
Links
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Statistics
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PSSM-Id: 438912
Aligned: 9 rows
Threshold Bit Score: 49.6755
Created: 30-Jun-2020
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Skp1 binding
Conserved site includes 22 residues -Click on image for an interactive view with Cn3D
Feature 1:Skp1 binding site [polypeptide binding site]
Evidence:
  • Structure:6BRO; Oryza sativa D3 in complex with SKP1-like protein 1A (ASK1), contacts at 4A
  • Comment:F-box proteins participate in SCF (Skp1-Cul1-F-box protein) complexes that function as ubiquitin E3 ligases, where the role of the F-box protein is to recruit target substrates.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         ## ##  #  ##  ##  ### #### ### ##   #  
6BRO_B         17 ILDLPEPLLLHILSFLtDVRSRHRAAlACGRMRAAERAT 55   Japanese rice
5HYW_A         37 ILDLPEPLLLHILSFLtDVRSRHRAAlACGRMRAAERAT 75   Japanese rice
PRW20983     4405 FADLPDAVLVHTLSFL-HLDERQRAAlTCRRFAALACSP 4442 Chlorella sorokiniana
RUS31439       16 LRSLSAETLIQVMSYL-PLRARVNLSsTCKQLNHLTYNS 53   Jimgerdemannia flammicorona
RXG61434      118 LTGLPQELLIKIASHL-NLKSILNLSvTCKRLHSSVQDN 155  common pillbug
XP_017299859  164 LRGMPYDVLVYIIKNYlNLQDFMNLVkTCKQLNNLVHEQ 202  Asian citrus psyllid
XP_017256889   10 ITDMGMDSLIHCASFL-NLQDISNLSlTCKYLNSLAYSD 47   Daucus carota subsp. sativus
EFJ34379        8 LLDLPSDALLLCAGSL-DLRDLSHLAmSCKRLRQIAYAD 45   Selaginella moellendorffii
KXN72407       53 FIHLPKPLQLKILSFL-NLRTRLNSSySCKLIRNLLRSG 90   Conidiobolus coronatus NRRL 28638

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