Conserved Protein Domain Family
F-box_EMI
?
cd22086: F-box_EMI 
F-box domain found in the early mitotic inhibitor (EMI) family of F-box proteins
The EMI family includes FBX5 (EMI1) and FBX43 (EMI2), which are anaphase-promoting complex/cyclosome (APC/C) inhibitors that bind APC/C-CCD20 (Cell division cycle protein 20) and/or APC/C-CDH1 (CDC20 homologue 1) complexes. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.
Links
?
Statistics
?
PSSM-Id: 438858
Aligned: 45 rows
Threshold Bit Score: 45.1805
Created: 12-Jan-2019
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
 
putative Skp1
Feature 1:putative Skp1 binding site [polypeptide binding site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1          #        #  ##  ##   # ##   ### #              
Q9UKT4       248 SELFRrg-lRHVLATILAQLsDMDLINVSkVSTTWKKILEddkGAFQLY 295 human
XP_014781401 153 SGLDQrn-iSAFLTKLVGYLsPEDIHSIYyVSKRWQVVCDkisQAQIKL 200 Octopus bimaculoides
PFX16917     115 SDLLAvn-gNKICQEICSYLePPELCRFAsVNRTWRNFVNgdtKTSTRW 162 Stylophora pistillata
CBY42061      68 EKLEErn-lLHIRDQIFGALdDRDIHNCSqVSKSWQNFMKt-iRHMRKK 114 Oikopleura dioica
XP_031549758 115 TELVQrn-cFKICRSICEYLnDRELSRFAsVSKSWRSFVKeepQIRDRL 162 Australian red waratah sea anemone
XP_002430866  26 LLLGErtghLPIVSKILSYLsDSDLQNVAkVSKTWQKLCLsdrVIAHKI 74  human body louse
XP_023939466 245 KMLYQeahvLPPVMKIFDYLsNEDIYRFTlVSPVWQRVWEdvsKAKAKK 293 squinting bush brown
XP_001626524 129 SELLTlg-aDRICYKICHKLgDSDLIRFAsVCQRWRQFVEd--FLSDRW 174 starlet sea anemone
XP_026686302  71 TELGGahdyFPVLSKIFAYLsDEDVASASrVSKSWNRVVNanvMVRHRL 119 Asian citrus psyllid
XP_018912873 179 YFLGVknihNPVLQRIYSYLsDHDLYNVArVSKTWHTLVKsnnSTRERI 227 Bemisia tabaci

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap