5JGH


Conserved Protein Domain Family
HMG-box_ABF2-like_rpt1

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cd22010: HMG-box_ABF2-like_rpt1 
Click on image for an interactive view with Cn3D
first high mobility group (HMG)-box found in Saccharomyces cerevisiae mitochondrial ARS-binding factor 2 (ABF2) and similar proteins
ABF2 is a close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria. It specifically binds to the autonomously replicating sequence 1 (ARS1). It might play a positive role in gene expression and replication. ABF2 contains two HMG-box domains. This model corresponds to the first one.
Statistics
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PSSM-Id: 438826
Aligned: 6 rows
Threshold Bit Score: 82.1989
Created: 25-Jun-2020
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
DNA binding
Conserved site includes 21 residues -Click on image for an interactive view with Cn3D
Feature 1:DNA binding site [nucleic acid binding site]
Evidence:
  • Structure:5JGH; Saccharomyces cerevisiae Abf2p binds DNA, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         ##### ##  ##  #          ###  ##  #  ##             #   #      #   
5JGH_A        23 PKRPTSAYFLYLQDHRSQFVKENPtlRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEF 90  Saccharomyces cerevisiae S288C
XP_005839979  72 PKRALSAYMLYANEVRADIVKKNPemKMTEISKVIGDKWKVLSADGKKKFENEAAKLKSEYEKEKAEY 139 Guillardia theta CCMP2712
Q02486        43 PKRPTSAYFLYLQDHRSQFVKENPtlRPAEISKIAGEKWQNLEADIKEKYISERKKLYSEYQKAKKEF 110 Saccharomyces cerevisiae S288C
XP_001451301 100 PRKPASACLVYIAEHRKDFGNENPdmNMAKVTKVLADKYSALSNKDKKKYEDDFQRKLEQYHKEIEIW 167 Paramecium tetraurelia stra...
XP_001744886   4 PKKPLRSYMRWFSANREQIKQDNPdaSNTELSQIGGQRWKEVSQEDKDKLEEDFQSELAEWETAVAAY 71  Monosiga brevicollis MX1
XP_003954761  62 PKRPSSAYFKYFMSIRDDLVRENPnaKVTEIAALGAKKWNTLNDFEKQSLRDKFTRELREYQVAKGRF 129 Kazachstania africana CBS 2517

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