1WGF


Conserved Protein Domain Family
HMG-box_UBF1_rpt4

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cd22001: HMG-box_UBF1_rpt4 
Click on image for an interactive view with Cn3D
fourth high mobility group (HMG)-box found in upstream-binding factor 1 (UBF1) and similar proteins
UBF1, also called UBTF, nucleolar transcription factor 1, or auto-antigen NOR-90, is a nucleolar transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. UBF1 contains six HMG-box domains. This model corresponds to the fourth one.
Statistics
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PSSM-Id: 438817
Aligned: 20 rows
Threshold Bit Score: 64.2402
Created: 8-Apr-2019
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
 
putative DNA
Conserved site includes 20 residues -Click on image for an interactive view with Cn3D
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           ## #####  ##      #           ##  #  ##      #   #  #   #  #   
1WGF_A        19 EKPKRPVSAMFIFSEEKRRQLQEERPELSEsELTRLLARMWNDLSEKKKAKYKAREAALKAQSERK 84  house mouse
KFM65586     476 ARPKKPLSAMFYFQQEKFAVARQKHPELSKqEVMKMLAKEYNELSDKKKDKYKKIAEEAKKAYDEG 541 Stegodyphus mimosarum
XP_002738418 454 DRPKKPISAIFLFCNERKEKFLKDHPGMSMkEANQTLMQKYRELPEKKQEKYKKKEADMKSQYEKQ 519 Saccoglossus kowalevskii
NP_001071845 436 ARPTTPISALFLYKRANRKKVEAQYRGMSTdEVTRLLARRYHELPEHKKHKYLKREKQLKEEYNEK 501 vase tunicate
XP_006807584 100 EYPKRPMPVNTWYYKEVFSKIKKKNPGISCaGLMKIASKEFSLLPDKKKAFYLEKYRNAYKEFTNK 165 Neolamprologus brichardi
KFB43101     132 KKPKYPPSAYNFYVKANLRTVKQEHPELSQhEILRKVAEQFKQLPDKKKQKYEQLAEQAKEEYKKE 197 Anopheles sinensis
XP_015818670  97 EVPKRPAQARYIYFKSKCAKFQTKHPEMGMtQVLCTLLQEYEALPQKEKALYEKKYAQKLVEYREK 162 turquoise killifish
XP_021163762  54 EHPKPPTPPKMRYVWKKMSKYRKKHPDVTIgQIVKILSKKYETLPDEKKDKYVQKHLLECGEYSRK 119 mummichog
XP_005812787 102 DFPKYPCSARIDYMKKNFSRLKKKHPRLTMtEIVVKALKKYNELPDEKKDEYEKRHALERAKYWRK 167 southern platyfish
XP_029933539  94 ALPVRPGPANAIFFQENFAKFKKKHPELSRqKLFKLASKKYTDLPPHKKAIYVNKFQLARDEYMQR 159 pinecone soldierfish

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